Year 2019, Volume 58 , Issue 2, Pages 149 - 153 2019-06-28

Üçüncü basamak bir hastaneye başvuran hastalarda HBsAg ve anti-HCV seroprevalansı: Altı yıllık retrospektif veriler
Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data

Derya Bayırlı Turan [1] , Tuba Kuruoğlu [2] , Defne Gümüş [3] , Fatma Kalaycı [4] , Kıvanç Şerefhanoğlu [5]


Amaç: Çalışmamızda hastanemize başvuran hastalarda Hepatit B ve Hepatit C seroprevalansının yaş gruplarına göre yıllar içindeki değişimini ve dağılımını araştırmayı amaçladık. Gereç ve Yöntem: İstanbul'da üçüncü basamak hastaneye altı yıl boyunca başvuran hastalar retrospektif olarak değerlendirildi. Aynı yıl içinde birden fazla başvuru yapan hastaların mükerrer sonuçları çalışma dışı bırakıldı. Kadın ve erkek hastalar 0-14, 14-25, 25-49 ve 49 yaş üzeri olmak üzere dört yaş grubuna ayrıldı. HBsAg ve anti-HCV testleri için elektrokemilüminesans yöntemi (Roche Cobas 6000, Almanya) kullanıldı. Bulgular: HBsAg pozitifliği %2,97 ve anti-HCV pozitifliği %1,35 oranında saptandı. HBsAg pozitifliği erkeklerde, antiHCV pozitifliği kadınlarda daha yüksek oranda idi. Anti-HCV ve HBsAg seroprevalansında 6 yıllık periyodda dikkati çekecek artış saptanmadı. HBsAg seroprevalansında özellikle 0-14 ve 14-25 yaş erkek gruplarında yıllar içinde azalma dikkati çekti. Diğer yaş gruplarında HBsAg seroprevalansında yıllar içinde bir azalma saptanmadı. Anti-HCV seroprevalansında ise yıllar içinde dikkati çekecek önemli bir fark saptanmadı. Sonuç: HBsAg pozitifliğinde özellikle 0-14 ve 14-25 yaş erkek gruplarında yıllar içinde azalma dikkati çekti. Diğer yaş gruplarında HBsAg seroprevalansında yıllar içinde bir azalma saptanmadı. Anti-HCV seroprevalansında ise yıllar içinde dikkati çekecek önemli bir fark saptanmadı.

Aim: We aimed to investigate the alteration and distribution of seroprevalence of hepatitis B and hepatitis C within the years according to age groups in patients who applied to our hospital. Materials and Methods: The patients have been evaluated for six years retrospectively who were admitted to third step hospital in Istanbul. The duplicate results of patients who submitted more than one application within the same year were excluded from this study. Male and female patients were divided into four age groups as 0-14, 14-25, 25- 49 and over 49 years old. Electrochemiluminescence method (Roche Cobas 6000, Germany) was used for HBsAg and anti-HCV assays. Results: HBsAg positivity was 2.97% and anti-HCV positivity was 1.35%. HBsAg positivity was higher in males, and anti-HCV positivity was higher in females. No significant increase in seroprevalences of anti-HCV and HBsAg was observed during the six years observation period. HBsAg seroprevalences decreased in years especially in 0-14 and 14-25 year-old male groups. HBsAg seroprevalence was not decreased in the other age groups over the years. There was no significant difference in anti-HCV seroprevalence over the years. HBsAg positivity was higher in males and anti-HCV positivity was higher in females. Anti-HCV and HBsAg seroprevalence were not significantly differed over the years. Conclusion: It was remarkable that HBsAg positivity rate had decreased over the years especially in 0-14 and 14-25 year-old males. Seroprevalence of HBsAg did not decrease in years in other age groups. There was no significant difference in the seroprevalence of anti-HCV during the measurement period.

  • You CR, Lee SW, Jang JW, Yoon S K. Update on hepatitis B virus infection. World J Gastroenterol 2014;20(37):13293-305.
  • Zampino R, Boemio A, Sagnelli C, et al. Hepatitis B virus burden in developing countries. World J Gastroenterol 2015;21(42):11941-53.
  • Caccamo G, Saffioti F, Raimondo G. Hepatitis B virus and hepatitis C virus dual infection. World J Gastroenterol 2014;28:20(40):14559-67.
  • WHO Hepatitis B. Available from: http://www.who.int/news-room/fact-sheets/detail/hepatitis-b.
  • Ergunay K, Balaban Y, Cosgun E, Hascelik G. Epidemiological trends in HBV infections at a reference centre in Turkey: An 11-year retrospective analysis. Ann Hepatol 2012;11(5):672-8.
  • WHO Hepatitis C. Available from: http://www.who.int/news-room/fact-sheets/detail/hepatitis-c.
  • Akarca US. Chronic hepatitis B. A guideline to diagnosis, approach, management, and follow‐up 2007. Turkish Association for the Study of Liver. Turk J Gastroenterol 2008;19(4):207‐30.
  • Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: Epidemiology and vaccination. Epidemiol Rev 2006;28(1):112-25.
  • Iqbal K, Klevens RM, Kainer MA, et al. Epidemiology of acute hepatitis B in the United States from population-based surveillance, 2006-2011. Clin Infect Dis 2015;61(4):584-92.
  • Toy M, Önder FO, Wörmann T, et al. Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: A systematic review. BMC Infect Dis 2011;11(2):337.
  • Alam MM, Zaidi SZ, et al. Molecular epidemiology of hepatitis B virus genotypes in Pakistan. BMC Infect Dis 2007;7(1):115.
  • WHO Hepatitis. Available from: http://www.who.int/ mediacentre /factsheets/ fs204
  • Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence. Hepatology 2013;57(4):1333-42.
  • Lee MH, Yang HI, Yuan Y, L'Italien G, Chen CJ. Epidemiology and natural history of hepatitis C virus infection. World J Gastroenterol 2014;28(20):9270-80.
  • Niu Z, Zhang PA,Tong YQ. Age and gender distribution of hepatitis C virus prevalence and genotypes of individuals of physical examination in Wu Han, Central China. Springer Plus 2016;13(5):1557.
  • Gower E, Estes C, Blach S, Razavi-Shearer K, Razavi H. Global epidemiology and genotype distribution of the hepatitis C virus infection. J Hepatol 2014;61(1):45-57.
  • Ni YH, Huang LM, Chang MH, et al. Two decades of universal hepatitis B vaccination in Taiwan: Impact and Implication for future strategies. Gastroenterology 2007;132(4):1287-93.
  • Liang X, Bi S, Yang W, et al. Epidemiological serosurvey of hepatitis B in China-declining HBV prevalence due to hepatitis B vaccination. Vaccine 2009;27(47):6550-7.
  • Turhanoğlu M, Onur A, Bilman FB, Ayaydın Z, Aktar GS. Eight-year seroprevalence of HBV, HCV and HIV in Diyarbakir Training and Research Hospital. Int J Med Sci 2013;12:10(11):1595-601.
  • Pépin J, Lavoie M, Pybus OG, et al. Risk factors for hepatitis C virus transmission in colonial Cameroon. Clin Infect Dis 2010;51(7):768-76.
  • Westbrook RH, Dusheiko. Natural history of hepatitis. C J Hepatol 2014;61(1):58-68.
  • Yapalı S. Seroprevalance of hepatitis B and C infections in Turkey. Turk J Gastroenterol 2017;28(2):147-8.
  • Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WL, Alter MJ. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med 2006;144(10):705-14.
  • Rantala M, van de Laar MJ. Surveillance and epidemiology of hepatitis B and C in Europe-a review. Euro Surveill 2008;13(21):18880.
  • Baden R, Rockstroh JK, Buti M. Natural history and management of hepatitis C: Does sex play a role? J Infect Dis 2014;15;209(3):81-5.
  • Galani BRT, Njouom R, Moundipa PF. Hepatitis C in Cameroon: What is the progress from 2001 to 2016? J Transl Int Med 2016;1(4):162-9.
Primary Language en
Subjects Health Care Sciences and Services
Journal Section Research Articles
Authors

Orcid: 0000-0002-7505-341X
Author: Derya Bayırlı Turan (Primary Author)
Institution: İstanbul Yeni Yüzyıl University School of Medicine, Gaziosmanpaşa Hospital, Department of Infectious Diseases and Clinical Microbiology, İstanbul
Country: Turkey


Orcid: 0000-0003-3805-367X
Author: Tuba Kuruoğlu
Institution: Ondokuz Mayıs University School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Samsun
Country: Turkey


Orcid: 0000-0003-4070-6924
Author: Defne Gümüş
Institution: İstanbul Yeni Yüzyıl University School of Medicine, Department of Medical Microbiology and Clinical Microbiology, İstanbu
Country: Turkey


Orcid: 0000-0002-0028-5646
Author: Fatma Kalaycı
Institution: İstanbul Yeni Yüzyıl University School of Medicine, Department of Medical Microbiology and Clinical Microbiology, İstanbu
Country: Turkey


Orcid: 0000-0003-0585-8797
Author: Kıvanç Şerefhanoğlu
Institution: İstanbul Yeni Yüzyıl University School of Medicine, Gaziosmanpaşa Hospital, Department of Infectious Diseases and Clinical Microbiology, İstanbul
Country: Turkey


Dates

Publication Date : June 28, 2019

Bibtex @research article { etd502958, journal = {Ege Tıp Dergisi}, issn = {1016-9113}, eissn = {2147-6500}, address = {}, publisher = {Ege University}, year = {2019}, volume = {58}, pages = {149 - 153}, doi = {10.19161/etd.502958}, title = {Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data}, key = {cite}, author = {Bayırlı Turan, Derya and Kuruoğlu, Tuba and Gümüş, Defne and Kalaycı, Fatma and Şerefhanoğlu, Kıvanç} }
APA Bayırlı Turan, D , Kuruoğlu, T , Gümüş, D , Kalaycı, F , Şerefhanoğlu, K . (2019). Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data. Ege Tıp Dergisi , 58 (2) , 149-153 . DOI: 10.19161/etd.502958
MLA Bayırlı Turan, D , Kuruoğlu, T , Gümüş, D , Kalaycı, F , Şerefhanoğlu, K . "Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data". Ege Tıp Dergisi 58 (2019 ): 149-153 <http://egetipdergisi.com.tr/en/issue/44438/502958>
Chicago Bayırlı Turan, D , Kuruoğlu, T , Gümüş, D , Kalaycı, F , Şerefhanoğlu, K . "Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data". Ege Tıp Dergisi 58 (2019 ): 149-153
RIS TY - JOUR T1 - Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data AU - Derya Bayırlı Turan , Tuba Kuruoğlu , Defne Gümüş , Fatma Kalaycı , Kıvanç Şerefhanoğlu Y1 - 2019 PY - 2019 N1 - doi: 10.19161/etd.502958 DO - 10.19161/etd.502958 T2 - Ege Tıp Dergisi JF - Journal JO - JOR SP - 149 EP - 153 VL - 58 IS - 2 SN - 1016-9113-2147-6500 M3 - doi: 10.19161/etd.502958 UR - https://doi.org/10.19161/etd.502958 Y2 - 2018 ER -
EndNote %0 Ege Tıp Dergisi Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data %A Derya Bayırlı Turan , Tuba Kuruoğlu , Defne Gümüş , Fatma Kalaycı , Kıvanç Şerefhanoğlu %T Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data %D 2019 %J Ege Tıp Dergisi %P 1016-9113-2147-6500 %V 58 %N 2 %R doi: 10.19161/etd.502958 %U 10.19161/etd.502958
ISNAD Bayırlı Turan, Derya , Kuruoğlu, Tuba , Gümüş, Defne , Kalaycı, Fatma , Şerefhanoğlu, Kıvanç . "Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data". Ege Tıp Dergisi 58 / 2 (June 2019): 149-153 . https://doi.org/10.19161/etd.502958
AMA Bayırlı Turan D , Kuruoğlu T , Gümüş D , Kalaycı F , Şerefhanoğlu K . Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data. Ege Tıp Dergisi. 2019; 58(2): 149-153.
Vancouver Bayırlı Turan D , Kuruoğlu T , Gümüş D , Kalaycı F , Şerefhanoğlu K . Seroprevalence of HBsAg and anti-HCV for patients who admitted to third step hospital: Six-year retrospective data. Ege Tıp Dergisi. 2019; 58(2): 153-149.