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Stroke and Therapeutic Hypothermia

Year 2016, Volume: 25 Issue: 3, 351 - 368, 30.09.2016
https://doi.org/10.17827/aktd.237674

Abstract

Stroke is significant cause of morbidity and mortality caused by disruption of blood flow. Neural injury occurs with two stage; while primary neural injury occurs with disruption of blood flow, after days and hours with metabolic processes secondary injury develops in tissues which is non injured in the first stage. Therefore it is important to prevent and treat the secondary injury as much as preventing and treating the primary neural injury. In this article developing pathophysiological changes after stroke, mechanisms of therapeutic hypothermia, application methods, the factors that determine the effectiveness, side effects and complications were reviewed.

İnme ve Terapötik Hipotermi

Year 2016, Volume: 25 Issue: 3, 351 - 368, 30.09.2016
https://doi.org/10.17827/aktd.237674

Abstract

İnme, beyin kan akımının bozulmasıyla meydana gelen önemli bir morbidite ve mortalite nedenidir. İnmede nöral hasar iki aşamada oluşur; akımın bozulmasıyla primer nöral hasar meydana gelirken, saatler ya da günler sonra gelişen metabolik süreçlerle de ilk aşamada zedelenmeyen dokuda sekonder nöral hasar oluşur. Dolayısıyla primer hasarın önlenmesi ve tedavisi kadar, sekonder nöral hasarın önlenmesi ve tedavisi de önemlidir. Bu derlemede, inme sonrası gelişen patofizyolojik değişiklikler ile terapötik hipoterminin etki mekanizmaları, uygulama yöntemleri, etkinliğini belirleyen faktörler, yan etkileri ve komplikasyonları incelenmiştir.

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Details

Primary Language English
Subjects Health Care Administration
Journal Section Review
Authors

Özlem Özkan Kuşcu

Dilek Özcengiz This is me

Publication Date September 30, 2016
Acceptance Date January 19, 2016
Published in Issue Year 2016 Volume: 25 Issue: 3

Cite

AMA Özkan Kuşcu Ö, Özcengiz D. Stroke and Therapeutic Hypothermia. aktd. September 2016;25(3):351-368. doi:10.17827/aktd.237674