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Evaluation of the Effects of Smoking on the Endocrine System

Year 2024, Volume: 1 Issue: 1, 34 - 42, 28.02.2024

Büşra Şahin Mazlumoğlu Nagihan Karagöl Şaziye Sezin Yücelik

https://doi.org/10.5281/zenodo.10712357

Abstract

Tüm dünyada yaygın olarak kullanılan sigara dünya çapında önlenebilir hastalık ve ölümlerin önde gelen nedenidir. Sigaranın küresel olarak kullanımının en önemli sebebi; içerisindeki nikotin ve diğer toksik bileşiklerin bağımlılık potansiyelinin yüksek olmasındandır. Sigara kullanımı ile dumanına aktif ve pasif maruziyet sonucu pek çok kimyasal bileşik ve küçük partikül akciğerlerden inhale edilerek hızla kan dolaşımına girer. Bu maddeler ise kardiyovasküler sistem başta olmak üzere vücutta hemen hemen tüm organ ve sistemleri etkileyebilir. Endokrin sistem üzerine etkileri de son yıllarda önemli bir araştırma konusu olup azalmış fertilite, olumsuz gebelik sonuçları ve yavrularda uzun vadeli olumsuz etkileri gibi reprodüktif sistem ile ilişkili pek çok araştırma yapılmıştır. Bununla birlikte erişkin fizyolojisi ve sağlıklı gelişim için esansiyel olan tiroid hormonları ile adrenal hormonlar üzerine etkileri de çalışmalarda tartışma konusudur. Son olarak yine endokrin bozucu etkilerinden kaynaklı diyabet riskindeki artış ile ilişkisi de çalışmalarda ön plana çıkmaktadır. Bu derleme kapsamında da sigaranın endokrin sistem üzerine etkilerinin değerlendirildiği çalışmalar derlenmiş ve küresel bir problem haline gelen sigara kullanımı için gerekli önlemlerin alınmasının; gelecek nesillerde sigaranın tetiklediği diyabet, kadın ve erkek üreme sistemi bozuklukları, tiroid hastalıklarının önlenmesine katkı sağlayacağı vurgulanmıştır.

Keywords

Sigara endokrin bozucular tiroid diyabet üreme sistemi

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Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi

Year 2024, Volume: 1 Issue: 1, 34 - 42, 28.02.2024

Büşra Şahin Mazlumoğlu Nagihan Karagöl Şaziye Sezin Yücelik

https://doi.org/10.5281/zenodo.10712357

Abstract

Tüm dünyada yaygın olarak kullanılan sigara, dünya çapında önlenebilir hastalık ve ölümlerin önde gelen nedenlerinden biridir. Sigaranın küresel olarak kullanımının en önemli sebebi; içerisindeki nikotin ve diğer toksik bileşiklerin bağımlılık potansiyelinin yüksek olmasındandır. Sigara dumanına aktif ve pasif maruziyet sonucu pek çok kimyasal bileşik ve küçük partikül akciğerlerden inhale edilerek hızla kan dolaşımına girer. Bu maddeler ise kardiyovasküler sistem başta olmak üzere vücutta hemen hemen tüm organ ve sistemleri etkileyebilir. Sigara kullanımının endokrin sistem üzerine etkileri de son yıllarda önemli bir araştırma konusu haline gelmiş olup, azalmış fertilite, gebelikle ilgili istenmeyen sonuçlar ve yavrularda uzun vadeli olumsuz etkiler gibi reprodüktif sistem ile ilişkili pek çok araştırma yapılmıştır. Bununla birlikte erişkin fizyolojisi ve sağlıklı gelişim için esansiyel olan tiroid hormonları ile adrenal hormonlar üzerine etkileri de çalışmalarda tartışma konusudur. Son olarak yine endokrin bozucu etkilerinden kaynaklı diyabet riskindeki artış ile ilişkisi de çalışmalarda ön plana çıkmaktadır. Bu çalışma kapsamında, sigara kullanımının endokrin sistem üzerine etkilerinin değerlendirildiği çalışmalar derlenmiştir. Söz konusu çalışmaların sonuçları doğrultusunda, giderek yaygınlaşan sigara kullanımının önüne geçilerek sigaranın tetiklediği diyabet, kadın ve erkek üreme sistemi bozuklukları, tiroid ile ilgili problemler gibi kronik hastalıkların önlenebileceği vurgulanmıştır.

Keywords

Sigara Endokrin bozucu kimyasal maddeler Tiroid Diyabet Üreme sistemi

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  • Abdel Fattah, S., Rizk, A.-E., Motawie, A., Abd El-Galil, T., & El Sebaie, M. (2019). Effects of nicotine on rat adrenal gland: crosstalk between oxidative and inflammatory markers, and amelioration by melatonin. Biotechnic & Histochemistry, 94(4), 234-243.
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There are 88 citations in total.

Details

Primary Language Turkish
Subjects Pharmaceutical Toxicology, Medical Pharmacology
Journal Section Reviews
Authors

Büşra Şahin Mazlumoğlu 0000-0002-2357-0538

Nagihan Karagöl 0000-0001-9173-6571

Şaziye Sezin Yücelik

Publication Date February 28, 2024
Published in Issue Year 2024 Volume: 1 Issue: 1

Cite

APA Şahin Mazlumoğlu, B., Karagöl, N., & Yücelik, Ş. S. (2024). Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi. Current Research in Health Sciences, 1(1), 34-42. https://doi.org/10.5281/zenodo.10712357
AMA Şahin Mazlumoğlu B, Karagöl N, Yücelik ŞS. Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi. Curr Res Health Sci. February 2024;1(1):34-42. doi:10.5281/zenodo.10712357
Chicago Şahin Mazlumoğlu, Büşra, Nagihan Karagöl, and Şaziye Sezin Yücelik. “Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi”. Current Research in Health Sciences 1, no. 1 (February 2024): 34-42. https://doi.org/10.5281/zenodo.10712357.
EndNote Şahin Mazlumoğlu B, Karagöl N, Yücelik ŞS (February 1, 2024) Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi. Current Research in Health Sciences 1 1 34–42.
IEEE B. Şahin Mazlumoğlu, N. Karagöl, and Ş. S. Yücelik, “Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi”, Curr Res Health Sci, vol. 1, no. 1, pp. 34–42, 2024, doi: 10.5281/zenodo.10712357.
ISNAD Şahin Mazlumoğlu, Büşra et al. “Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi”. Current Research in Health Sciences 1/1 (February 2024), 34-42. https://doi.org/10.5281/zenodo.10712357.
JAMA Şahin Mazlumoğlu B, Karagöl N, Yücelik ŞS. Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi. Curr Res Health Sci. 2024;1:34–42.
MLA Şahin Mazlumoğlu, Büşra et al. “Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi”. Current Research in Health Sciences, vol. 1, no. 1, 2024, pp. 34-42, doi:10.5281/zenodo.10712357.
Vancouver Şahin Mazlumoğlu B, Karagöl N, Yücelik ŞS. Sigara Kullanımının Endokrin Sistem Üzerine Etkilerinin Değerlendirilmesi. Curr Res Health Sci. 2024;1(1):34-42.
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