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Investigation of the Effect of Deep Brain Stimulation Surgery on Mobility, Emotional Status and Quality of Life in a Patient with Dystonia: Case Repor

Year 2015, Volume: 40 Issue: 2, 358 - 363, 28.09.2015
https://doi.org/10.17826/cutf.68279

Abstract

The aim of our study is to examine the effects of deep brain stimulation (DBS) surgery on severity of dystonia, mobility, emotional status, and health-related quality of life (QOL) in patient with dystonia. This study was carried out on a case of 41-year-old female with complaints of neck and arm pain, involuntary contraction for 30 years. GPİ-DBS was applied to the patient bilaterally in 2010. Global Dystonia Scale (GDS) was used to assess the severity of the patient's dystonia, effects on body parts and functions. Beck Depression Inventory (BDI) was applied to detect emotional status. 12- Meter Walking Test (mobility) and Short Form-36 (SF-36) were used to evaluate quality of life. All assessments were repeated prior to surgery, after surgery 1st year and 3rd years. Prior to surgery, GDS was 112. Postoperative 1st and 3rd years, GDS was respectively 69/84. Prior to surgery, the total BDI score was 31. Postoperative 1st and 3rd years, GDS was respectively 28/40. 12-Meter Walking Test results were respectively 18/10/15 sec. for the prior to surgery, postoperative 1st. and 3rd years. General health status and physical function subscales of SF-36, respectively, prior to surgery were 30/75, postoperative 1st year was 60/85 and 3rd years were 20/35. GPI-DBS is a surgical procedure, which has positive effect on mobility, emotional status and QOL, in patient with dystonia.

References

  • Vercueil L, Pollak P, Fraix V, Caputo E, Moro E, Benazzouz A, et al. Deep Brain Stimulation in the Treatment of Severe Dystonia. J Neurol. 2001;2:695– 700.
  • Manji H, Howard RS, Miller DH, Hirsch NP, Carr L, Bahtia K, et al. Status Dystonicus: the Syndrome and its Management. Brain. 1998;121:243–52.
  • Balash Y, Giladi N. Efficacy of Pharmacological Treatment of Dystonia: Evidence-Based Review Including Meta-analysis of the Effect of BTX and Other Cure Options. Eur J Neurol. 2004;11:361–70.
  • Fahn S, Bressman SB, Marsden CD. Classification of dystonia. Adv Neurol. 1998;78:1-10.
  • Fahn S. Concept and classification of dystonia. Adv Neurol. 1998;50:1–8.
  • Vidailhet M, Vercueil L, Houeto JL, Houeto JL, Krystkowiak P, Benabid AL, et al. Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia. N Engl J Med. 2005;352:459– 67.
  • Thobois S, Danaila T, Polo G, Simon E, Mertens P, Broussolle E. Deep-Brain Stimulation for Dystonia: Current Indications and Future Orientations. Future Neurology. 2014;9:77-87.
  • Benabid AL, Benazzouz A, Hoffmann D, Limousin P, Krack P, Pollak P. Long-term electrical inhibition of deep brain targets in movement disorders. Mov Disord. 1998;13:119-25.
  • Lozano AM, Abosch A. Pallidal stimulation for dystonia. Adv Neurol. 2004;94:301-8.
  • Cif L, El Fertit H, Vayssiere N, Hemm S, Hardouin E, Gannau A, Tuffery S, Coubes P. Treatment of dystonic syndromes by chronic electrical stimulation of the internal globus pallidus. Neurosurg Sci. 2003;47:52-5.
  • Vidailhet M, Vercueil L, Houeto JL, Krystkowiak P, Lagrange C, et al. Bilateral, pallidal, deep-brain stimulation in primary generalised dystonia: a prospective 3 year follow-up study Lancet Neurol. 2007;6:223–29.
  • Kiss ZHT, Doig-Beyaert K, Eliasziw M, Tsui J, Affenden A, Suchowersky O. et al. The Canadian Multicentre Study of Deep Brain Stimulation for Cervical Dystonia. Brain. 2007;130:2879-86.
  • Alterman RL, and Tagliati M. Deep Brain Stimulation for Dystonia: Patient Selection, Surgical Technique, and Programming the Open Neurosurgery Journal, 2011;4:29-35.
  • FitzGerald JJ, Rosendal F, De Pennington N, Joint C, Forrow B et al. Long-term outcome of deep brain stimulation in generalised dystonia: a series of 60 cases. J Neurol Neurosurg Psychiatry.2014; doi:10.1136/jnnp-2013-306833.
  • Kupsch A, Klaffke S, Kuhn AA, Meissner W, Arnold G, et al. The effects of frequency in pallidal deep brain stimulation for primary dystonia. J Neurol. 2003;250:1201–5.
  • Mueller J, Skogseid IM, Benecke R, Kupsch A, Trottenberg T, Poewe W et al. Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: results from a prospective, randomized sham-controlled trial. Mov Disord. 2008;23:131-4

Distonili Bir Hastada Derin Beyin Stimülasyon Cerrahisinin Mobilite, Emosyonel Durum ve Yaşam Kalitesi Üzerine Olan Etkisinin İncelenmesi: Olgu Sunumu

Year 2015, Volume: 40 Issue: 2, 358 - 363, 28.09.2015
https://doi.org/10.17826/cutf.68279

Abstract

Çalışmamızın amacı distonili bir hastada derin beyin stimülasyon cerrahisinin mobilite, emosyonel durum ve yaşam kalitesi üzerine olan etkilerini incelemektir. Çalışma, 30 yıldır boyun ve kolda istemsiz kasılma ve ağrı şikâyetleri olan 41 yaşında bayan bir olgu üzerinde gerçekleştirilmiştir. Hastaya 2010 yılında Bilateral Globus Pallidus İnterna (GPİ) yerleşimli derin beyin stimülasyon cerrahisi yapılmıştır. Hastanın distoni şiddetini, etkilediği vücut fonksiyonları ve kısımlarını değerlendirmek için Global Distoni Skoru kullanılmıştır. Emosyonel durumu belirlemek için Beck Depresyon Ölçeği, yaşam kalitesi için Kısa Form- 36(SF-36) ve mobilite durumunu değerlendirmek için 12 metre yürüme testi uygulanmıştır. Hastamızda bütün değerlendirmeler cerrahi öncesinde, cerrahiden sonra 1. yıl ve 3. yılda tekrar edilmiştir. Hastanın cerrahi öncesinde Global Distoni Skoru 112 iken cerrahi sonrası 1. yılda 69 ve 3. yılda 84 olarak kaydedilmiştir. Emosyonel durum toplam puanı cerrahi öncesinde 31 iken cerrahi sonrası 1. ve 3. yılda sırasıyla 28/40 kaydedilmiştir. 12 metre yürüme test sonuçları cerrahi öncesinde 18 sn iken, 1. yılda 10 sn ve 3. yılda 15 sn kaydedilmiştir. Yaşam kalitesi SF-36 alt ölçeklerinden genel sağlık durumu ve fiziksel fonksiyon cerrahi öncesinde sırasıyla 30/75 iken cerrahi sonrası 1.yıl 60/85 ve 3. yılda 20/35 olarak kaydedilmiştir. Distonili bir hastada GPİ derin beyin stimülasyon cerrahisi mobilite, emosyonel durum ve yaşam kalitesi üzerine olumlu yönde etkisi olan cerrahi bir yöntemdir.

References

  • Vercueil L, Pollak P, Fraix V, Caputo E, Moro E, Benazzouz A, et al. Deep Brain Stimulation in the Treatment of Severe Dystonia. J Neurol. 2001;2:695– 700.
  • Manji H, Howard RS, Miller DH, Hirsch NP, Carr L, Bahtia K, et al. Status Dystonicus: the Syndrome and its Management. Brain. 1998;121:243–52.
  • Balash Y, Giladi N. Efficacy of Pharmacological Treatment of Dystonia: Evidence-Based Review Including Meta-analysis of the Effect of BTX and Other Cure Options. Eur J Neurol. 2004;11:361–70.
  • Fahn S, Bressman SB, Marsden CD. Classification of dystonia. Adv Neurol. 1998;78:1-10.
  • Fahn S. Concept and classification of dystonia. Adv Neurol. 1998;50:1–8.
  • Vidailhet M, Vercueil L, Houeto JL, Houeto JL, Krystkowiak P, Benabid AL, et al. Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia. N Engl J Med. 2005;352:459– 67.
  • Thobois S, Danaila T, Polo G, Simon E, Mertens P, Broussolle E. Deep-Brain Stimulation for Dystonia: Current Indications and Future Orientations. Future Neurology. 2014;9:77-87.
  • Benabid AL, Benazzouz A, Hoffmann D, Limousin P, Krack P, Pollak P. Long-term electrical inhibition of deep brain targets in movement disorders. Mov Disord. 1998;13:119-25.
  • Lozano AM, Abosch A. Pallidal stimulation for dystonia. Adv Neurol. 2004;94:301-8.
  • Cif L, El Fertit H, Vayssiere N, Hemm S, Hardouin E, Gannau A, Tuffery S, Coubes P. Treatment of dystonic syndromes by chronic electrical stimulation of the internal globus pallidus. Neurosurg Sci. 2003;47:52-5.
  • Vidailhet M, Vercueil L, Houeto JL, Krystkowiak P, Lagrange C, et al. Bilateral, pallidal, deep-brain stimulation in primary generalised dystonia: a prospective 3 year follow-up study Lancet Neurol. 2007;6:223–29.
  • Kiss ZHT, Doig-Beyaert K, Eliasziw M, Tsui J, Affenden A, Suchowersky O. et al. The Canadian Multicentre Study of Deep Brain Stimulation for Cervical Dystonia. Brain. 2007;130:2879-86.
  • Alterman RL, and Tagliati M. Deep Brain Stimulation for Dystonia: Patient Selection, Surgical Technique, and Programming the Open Neurosurgery Journal, 2011;4:29-35.
  • FitzGerald JJ, Rosendal F, De Pennington N, Joint C, Forrow B et al. Long-term outcome of deep brain stimulation in generalised dystonia: a series of 60 cases. J Neurol Neurosurg Psychiatry.2014; doi:10.1136/jnnp-2013-306833.
  • Kupsch A, Klaffke S, Kuhn AA, Meissner W, Arnold G, et al. The effects of frequency in pallidal deep brain stimulation for primary dystonia. J Neurol. 2003;250:1201–5.
  • Mueller J, Skogseid IM, Benecke R, Kupsch A, Trottenberg T, Poewe W et al. Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: results from a prospective, randomized sham-controlled trial. Mov Disord. 2008;23:131-4
There are 16 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Filiz Altuğ

Ayşe Ünal This is me

Gönül Kılavuz This is me

Erdoğan Kavlak This is me

Feridun Acar This is me

Uğur Cavlak This is me

Publication Date September 28, 2015
Published in Issue Year 2015 Volume: 40 Issue: 2

Cite

MLA Altuğ, Filiz et al. “Investigation of the Effect of Deep Brain Stimulation Surgery on Mobility, Emotional Status and Quality of Life in a Patient With Dystonia: Case Repor”. Cukurova Medical Journal, vol. 40, no. 2, 2015, pp. 358-63, doi:10.17826/cutf.68279.