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Presistolik dalga ankilozan spondilitte subklinik sol ventrikül diyastolik disfonksiyonu için bir belirteç olabilir mi?

Year 2020, Volume: 45 Issue: 3, 880 - 890, 30.09.2020
https://doi.org/10.17826/cumj.690505

Abstract

Amaç: Bu çalışmanın amacı, ankilozan spondilit hastalarında diyastolik disfonksiyonun saptanmasında presistolik dalganın önemini değerlendirmektir.
Gereç ve Yöntem: Kesitsel çalışmamıza 59 hasta ve 65 sağlıklı kontrol dahil edildi. Ankilozan Spondilit Hastalığı Aktivite Skoru, Bath Ankilozan Spondilit Metrology indeks, Maastricht Ankilozan Spondilit Entesit Skoru ve Bath Ankilozan Spondilit Fonksiyonel İndeksi değerlendirildi. Doppler doku görüntüleme ve presistolik dalga ölçümleri yapıldı.
Bulgular: Hastaların % 37.3'ünde ve kontrol grubunun % 16.9'unda olmak üzere tüm çalışma popülasyonunun% 26.6'sında presistolik dalga saptandı. Hasta ve kontrol grupları presistolik dalganın varlığına veya yokluğuna göre iki gruba ayrıldığında; miyokardiyal performans indeksi, transmitral E dalga hızı, E/A oranı, sol ventrikül çıkış yolu velositesi ve septal e 'dalga hızı, her iki grupta da presiktolik dalgası olanlarda istatistiksel olarak anlamlı oranda farklıydı. Tek değişkenli modelde, yüksek c-reaktif protein seviyesi, artmış BASMI ve BASFI skorları ve artmış miyokard performans indeksi, ankilozan spondilit hastalarında presistolik dalga varlığı için risk faktörü olarak belirlenmiştir.
Sonuç: Ekokardiyografik incelemede presistolik dalganın varlığı, ankilozan spondilit hastalarında prognostik önemi olan sol ventrikül diyastolik fonksiyonu hakkında önemli bilgiler sağlayabilir.

References

  • 1) McCarey D, Sturrock RD. Comparison of cardiovascular risk in ankylosing spondylitis and rheumatoid arthritis. Clin Exp Rheumato. 2009;27:124–6. 2) Roifman I, Beck PL, Anderson TJ, Eisenberg MJ, Genest J. Chronic inflammatory diseases and cardiovascular risk: a systematic review. Can J Cardiol. 2011;27:174–82 3) Chou CH, Lin MC, Peng CL, Wu YC, Sung FC, Kao CH, et al. A nationwide population-based retrospective cohort study: increased risk of acute coronary syndrome in patients with ankylosing spondylitis. Scand J Rheumatol. 2011; 43: 132–6. 4) Bakland G, Gran JT, Nossent JC. Increased mortality in ankylosing spondylitisis related to disease activity. Ann Rheum Dis. 2011;70:1921–5. 5) Han C, Robinson DWJr, Hackett MV, Paramore LC, Fraeman KH, Bala MV. Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, andankylosing spondylitis. J Rheumato. 2006;33:2167–72. 6) Peters MJ, van der Horst-Bruinsma IE, Dijkmans BA, Nurmohamed MT. Cardiovascular risk profile of patients with spondylarthropathies, particularly ankylosing spondylitis and psoriatic arthritis. Semin Arthritis Rheum. 2004;34:585–92. 7) Haroon NN, Paterson JM, Li P, Inman RD, Haroon N. Patients With Ankylosing Spondylitis Have Increased Cardiovascular and Cerebrovascular Mortality: A Population-Based Study. Ann Intern Med. 2015;163: 409 8) Heslinga SC, Van Dongen CJ, Konings TC, Peters MJ, Van der Horst-Bruinsma IE, Smulders YM, et al. Diastolic left ventricular dysfunction in ankylosing spondylitis–a systematic review and meta-analysis. Semin Arthritis Rheum. 2014;44:14–9. 9) Chatterjee K, Massie B. Systolic and diastolic heart failure: differences and similarities. J Card Fail. 2007;13:569–76. 10) Paulus WJ, Tschöpe C. A novel paradigm for heart failure with preserved ejection fraction:comorbidities drive myocardial dysfunction andr emodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol. 2013;62:263–71. 11) Korkmaz L, Akyüz AR, Gurbak I, Erkan H, Dursun I, Celik S. Presystolic A wave may predict increased arterial stiffness in asymptomatic individuals. Blood Press Monit. 2016;21:144–148. 12) Machado P, Landewé R, Lie E, Kvien TK, Braun J, Baker D, et al. Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores. Ann Rheum Dis. 2011;70:47-53. 13) Machado PM, Landewé R, Heijde DV. Assessment of SpondyloArthritis international Society (ASAS). Ankylosing Spondylitis Disease Activity Score (ASDAS): 2018 update of the nomenclature for disease activity states. Ann Rheum Dis. 2018;77:1539-1540. 14) Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garrett SL, Calin A. Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol 1994;21:1694–8.
 15) Sieper J, Rudwaleit M, Baraliakos X, Brandt J, Braun J, Burgos-Vargas R, et al. The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis. 2009;68 Suppl 2:ii1-44.
  • 16) Calin A, Jones SD, Garrett SL, Kennedy LG. Bath Ankylosing Spondylitis Functional Index. Br J Rheumatol. 1995;34:793–4. 17) Ozer HT, Sarpel T, Gulek B, Alparslan ZN, Erken E. The Turkish version of the Bath Ankylosing Spondylitis Functional Index: reliability and validity. Clin Rheumatol. 2005; 24:123-8. 18) Heuft-Dorenbosch L, Spoorenberg A, van Tubergen A, Landewé R, van ver Tempel H, Mielants H, et al. Assessment of enthesitis in ankylosing spondylitis. Ann Rheum Dis. 2003;62:127–32.
 19) Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Chamber Quantification Writing Group, American Society of Echocardiography’s Guidelines and Standards Committee, European Association of Echocardiography. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005; 18: 1440–1463 20) Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification. Eur J Echocardiogr. 2006;7:79-108. 21) Tei C1, Ling LH, Hodge DO, Bailey KR, Oh JK, Rodeheffer RJ, et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function - a study in normals and dilated cardiomyopathy. J Cardiol. 1995; 26: 357-366 22) Sveälv BG, Täng MS, Klingberg E, Forsblad-d'Elia H, Bergfeldt L. Prevalence of diastolic dysfunction in patients with ankylosing spondylitis: a cross-sectional study. Scand J Rheumatol. 2015; 44: 111-7. 23) Armstrong WF, Ryan T, Feigenbaum H. Feigenbaum’s Echocardiography. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2010:545. 24) Mittal SR, Pancholi N. Left ventricular outflow tract presystolic flow velocity--another marker of left ventricular diastolic function. Int J Cardiovasc Imaging. 2002;18:249–256. 25) Akyüz AR, Turan T, Gürbak İ, Korkmaz L, Ağaç MT, Çelik Ş. The relationship between presystolic wave and subclinical left ventricular dysfunction in asymptomatic hypertensive patients. Blood Press Monit. 2016;2:277–281. 26) Adar A, Kırış A, Bülbül Y, Bektaş H, Acat M, Casim H, Onalan O, et al. Association of fragmented QRS with subclinical left ventricular dysfunction in patients with obstructive sleep apnea. Med Princ Pract. 2015; 24: 376–381. 27) Vizzardi E, Bonadei I, Teli M, Caretta G, Maiandi C, Madureri A, et al. Usefulness of left atrial diametres and volumes for the evaluation of left ventricular diastolic function. Recenti Prog Med. 2009; 100: 294-8. 28) Appleton CP, Firstenberg MS, Garcia MJ, Thomas JD. The echo-Doppler evaluation of left ventricular diastolic function. A current perspective. Cardiol clin. 2000; 18: 513–546. 29) Ommen SR, Nishimura RA. A clinical approach to the assessment of left ventricular diastolic function by Doppler echocardiography: update 2003. Heart 2003; 89: 18-23. 30) Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: partII: causal mechanisms and treatment. Circulation 2002; 105: 1503–8. 31) Cuspidi C, Sala C, Muiesan ML, De Luca N, Schillaci G. Right ventricular hypertrophy in systemic hypertension: an updated review of clinical studies. J Hypertens. 2013; 31: 858–65. 32) Okan T, Sari I, Akar S, Cece H, Goldeli O, Guneri S, et al. Ventricular diastolic function of ankylosing spondylitis patients by using conventional pulsed wave Doppler, myocardial performance index and tissue Doppler imaging. Echocardiography 2008;25:47–56. 33) Nagueh SF, Appleton CP, Gillebert TC, Marino PN, Oh JK, Smiseth OA, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiog. 2009; 22: 107-33.

Could presystolic wave be a predictor for subclinical left ventricular diastolic dysfunction in ankylosing spondylitis?

Year 2020, Volume: 45 Issue: 3, 880 - 890, 30.09.2020
https://doi.org/10.17826/cumj.690505

Abstract

Purpose: The aim of this study was to evaluate the clinical significance of presystolic wave in the detection of diastolic dysfunction in ankylosing spondylitis patients.
Materials and Methods: In this cross-sectional study, 59 patients and 65 healthy controls were included in the study. Ankylosing Spondylitis Disease Activity Score, Bath Ankylosing Spondylitis Metrology Index, Maastricht Ankylosing Spondylitis Enthesitis Score and Bath Ankylosing Spondylitis Functional Index was eveluated. The Doppler tissue-imaging and presystolic wave measurements were performed by same cardiologist who was blinded to study details.
Results: Presystolic wave was detected in 26.6% of the whole study population; in 37.3% of patients and 16.9% of the control group. When the patient and control groups were divided into two subgroups according to the presence or absence of presystolic wave; myocardial performance index, transmitral E wave velocity, E/A ratio, left ventricular outflow tract velocity and septal e’ wave velocity were statistically significant in subjects with presence presystolic wave in both groups. In the univariate model, high c-reactive protein level, increased BASMI and BASFI scores and elevated myocardial performance index were determined as risk factors for the presence of presystolic wave in ankylosing spondylitis patients.
Conclusion: The assessment of presystolic wave on echocardiography examination may provide important information about the left ventricul diastolic function, which has a prognostic impact for ankylosing spondylitis patients. 

References

  • 1) McCarey D, Sturrock RD. Comparison of cardiovascular risk in ankylosing spondylitis and rheumatoid arthritis. Clin Exp Rheumato. 2009;27:124–6. 2) Roifman I, Beck PL, Anderson TJ, Eisenberg MJ, Genest J. Chronic inflammatory diseases and cardiovascular risk: a systematic review. Can J Cardiol. 2011;27:174–82 3) Chou CH, Lin MC, Peng CL, Wu YC, Sung FC, Kao CH, et al. A nationwide population-based retrospective cohort study: increased risk of acute coronary syndrome in patients with ankylosing spondylitis. Scand J Rheumatol. 2011; 43: 132–6. 4) Bakland G, Gran JT, Nossent JC. Increased mortality in ankylosing spondylitisis related to disease activity. Ann Rheum Dis. 2011;70:1921–5. 5) Han C, Robinson DWJr, Hackett MV, Paramore LC, Fraeman KH, Bala MV. Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, andankylosing spondylitis. J Rheumato. 2006;33:2167–72. 6) Peters MJ, van der Horst-Bruinsma IE, Dijkmans BA, Nurmohamed MT. Cardiovascular risk profile of patients with spondylarthropathies, particularly ankylosing spondylitis and psoriatic arthritis. Semin Arthritis Rheum. 2004;34:585–92. 7) Haroon NN, Paterson JM, Li P, Inman RD, Haroon N. Patients With Ankylosing Spondylitis Have Increased Cardiovascular and Cerebrovascular Mortality: A Population-Based Study. Ann Intern Med. 2015;163: 409 8) Heslinga SC, Van Dongen CJ, Konings TC, Peters MJ, Van der Horst-Bruinsma IE, Smulders YM, et al. Diastolic left ventricular dysfunction in ankylosing spondylitis–a systematic review and meta-analysis. Semin Arthritis Rheum. 2014;44:14–9. 9) Chatterjee K, Massie B. Systolic and diastolic heart failure: differences and similarities. J Card Fail. 2007;13:569–76. 10) Paulus WJ, Tschöpe C. A novel paradigm for heart failure with preserved ejection fraction:comorbidities drive myocardial dysfunction andr emodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol. 2013;62:263–71. 11) Korkmaz L, Akyüz AR, Gurbak I, Erkan H, Dursun I, Celik S. Presystolic A wave may predict increased arterial stiffness in asymptomatic individuals. Blood Press Monit. 2016;21:144–148. 12) Machado P, Landewé R, Lie E, Kvien TK, Braun J, Baker D, et al. Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores. Ann Rheum Dis. 2011;70:47-53. 13) Machado PM, Landewé R, Heijde DV. Assessment of SpondyloArthritis international Society (ASAS). Ankylosing Spondylitis Disease Activity Score (ASDAS): 2018 update of the nomenclature for disease activity states. Ann Rheum Dis. 2018;77:1539-1540. 14) Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garrett SL, Calin A. Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol 1994;21:1694–8.
 15) Sieper J, Rudwaleit M, Baraliakos X, Brandt J, Braun J, Burgos-Vargas R, et al. The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis. 2009;68 Suppl 2:ii1-44.
  • 16) Calin A, Jones SD, Garrett SL, Kennedy LG. Bath Ankylosing Spondylitis Functional Index. Br J Rheumatol. 1995;34:793–4. 17) Ozer HT, Sarpel T, Gulek B, Alparslan ZN, Erken E. The Turkish version of the Bath Ankylosing Spondylitis Functional Index: reliability and validity. Clin Rheumatol. 2005; 24:123-8. 18) Heuft-Dorenbosch L, Spoorenberg A, van Tubergen A, Landewé R, van ver Tempel H, Mielants H, et al. Assessment of enthesitis in ankylosing spondylitis. Ann Rheum Dis. 2003;62:127–32.
 19) Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Chamber Quantification Writing Group, American Society of Echocardiography’s Guidelines and Standards Committee, European Association of Echocardiography. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005; 18: 1440–1463 20) Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification. Eur J Echocardiogr. 2006;7:79-108. 21) Tei C1, Ling LH, Hodge DO, Bailey KR, Oh JK, Rodeheffer RJ, et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function - a study in normals and dilated cardiomyopathy. J Cardiol. 1995; 26: 357-366 22) Sveälv BG, Täng MS, Klingberg E, Forsblad-d'Elia H, Bergfeldt L. Prevalence of diastolic dysfunction in patients with ankylosing spondylitis: a cross-sectional study. Scand J Rheumatol. 2015; 44: 111-7. 23) Armstrong WF, Ryan T, Feigenbaum H. Feigenbaum’s Echocardiography. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2010:545. 24) Mittal SR, Pancholi N. Left ventricular outflow tract presystolic flow velocity--another marker of left ventricular diastolic function. Int J Cardiovasc Imaging. 2002;18:249–256. 25) Akyüz AR, Turan T, Gürbak İ, Korkmaz L, Ağaç MT, Çelik Ş. The relationship between presystolic wave and subclinical left ventricular dysfunction in asymptomatic hypertensive patients. Blood Press Monit. 2016;2:277–281. 26) Adar A, Kırış A, Bülbül Y, Bektaş H, Acat M, Casim H, Onalan O, et al. Association of fragmented QRS with subclinical left ventricular dysfunction in patients with obstructive sleep apnea. Med Princ Pract. 2015; 24: 376–381. 27) Vizzardi E, Bonadei I, Teli M, Caretta G, Maiandi C, Madureri A, et al. Usefulness of left atrial diametres and volumes for the evaluation of left ventricular diastolic function. Recenti Prog Med. 2009; 100: 294-8. 28) Appleton CP, Firstenberg MS, Garcia MJ, Thomas JD. The echo-Doppler evaluation of left ventricular diastolic function. A current perspective. Cardiol clin. 2000; 18: 513–546. 29) Ommen SR, Nishimura RA. A clinical approach to the assessment of left ventricular diastolic function by Doppler echocardiography: update 2003. Heart 2003; 89: 18-23. 30) Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: partII: causal mechanisms and treatment. Circulation 2002; 105: 1503–8. 31) Cuspidi C, Sala C, Muiesan ML, De Luca N, Schillaci G. Right ventricular hypertrophy in systemic hypertension: an updated review of clinical studies. J Hypertens. 2013; 31: 858–65. 32) Okan T, Sari I, Akar S, Cece H, Goldeli O, Guneri S, et al. Ventricular diastolic function of ankylosing spondylitis patients by using conventional pulsed wave Doppler, myocardial performance index and tissue Doppler imaging. Echocardiography 2008;25:47–56. 33) Nagueh SF, Appleton CP, Gillebert TC, Marino PN, Oh JK, Smiseth OA, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiog. 2009; 22: 107-33.
There are 2 citations in total.

Details

Primary Language English
Subjects Cardiovascular Surgery
Journal Section Research
Authors

Çağlar Özmen 0000-0002-7285-991X

Neslihan Gökçen 0000-0003-3022-493X

Rabia Akıllı 0000-0003-4922-6556

Cuma Yeşildaş This is me 0000-0002-0940-8999

Ayhan Usal This is me 0000-0003-2579-4858

Publication Date September 30, 2020
Acceptance Date May 16, 2020
Published in Issue Year 2020 Volume: 45 Issue: 3

Cite

MLA Özmen, Çağlar et al. “Could Presystolic Wave Be a Predictor for Subclinical Left Ventricular Diastolic Dysfunction in Ankylosing Spondylitis?”. Cukurova Medical Journal, vol. 45, no. 3, 2020, pp. 880-9, doi:10.17826/cumj.690505.