An investigation of the relationship between postmenopausal bone density and the first delivery in adolescence
Abstract
Aim: To evaluate the relationship between postmenopausal bone density and first birth age.
Materials and Methods: All consecutive patients who were admitted to our menopausal outpatient clinic and met the study criteria were included in this study. Obstetric history and demographic characteristics of each patient were questioned, and the first birth ages were recorded. Bone density of the vertebra and femur were measured by dual energy x-ray absorptiometry (DEXA).
Results: A total of 80 patients were included in the study, 36 with a history of adolescent birth and 44 without a history of adolescent birth. No statistically significant difference was found between the groups in terms of age, duration of menopause, number of children, monthly income, body mass index, menopause type, occupational status, educational status, drug use, and obesity (p> 0.05). There was a statistically significant difference between the two groups of lumbar T, lumbar Z, femur T and femur Z scores (p <0.05).
Conclusion: Adolescent births may positively affect both the lomber and femur bone mineral density.
References
- Dehne KL, Riedner G. Adolescence--a dynamic concept. Reprod Health Matters. 2001; 9 (17): 11-5.
- Bryce J, Boschi-Pinto C, Shibuya K, Black RE; WHO Child Health Epidemiology Reference Group. WHO estimates of the causes of death in children. Lancet. 2005; 365 (9465): 1147-52.
- Türkiye İstatistik Kurumu, İl, yaş grubu ve cinsiyete göre nüfus. 2017. [Cited 19 November 2018]. Available from http://www.tuik.gov.tr/PreIstatistikTablo.do?istab_id=945.
- Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, Adölesan Doğurganlık ve Annelik. 2013 Türkiye Nüfus ve Sağlık Araştırması, Ankara, Türkiye, 2014. [Cited 19 November 2018]. Available from: http://www.hips.hacettepe.edu.tr/tnsa2013/rapor/TNSA_2013_ana_rapor.pdf
- Lloyd T, Lin HM, Eggli DF, Dodson WC, Demers LM, Legro RS. Adolescent Caucasian mothers have reduced adult hip bone density. Fertil Steril. 2002; 77 (1): 136-40.
- Ott SM, Scholes D, LaCroix AZ, Ichikawa LE, Yoshida CK, Barlow WE. Effects of contraceptive use on bone biochemical markers in young women. J Clin Endocrinol Metab. 2001; 86 (1): 179-85.
- Loro ML, Sayre J, Roe TF, Goran MI, Kaufman FR, Gilsanz V. Early identification of children predisposed to low peak bone mass and osteoporosis later in life. J Clin Endocrinol Metab. 2000; 85 (10): 3908-18.
- Cho GJ, Shin JH, Yi KW, et al. Adolescent pregnancy is associated with osteoporosis in postmenopausal women. Menopause. 2012; 19 (4): 456-60.
- Teerapornpuntakit J, Chanprapaph P, Charoenphandhu N. Previous Adolescent Pregnancy and Breastfeeding Does Not Negatively Affect Bone Mineral Density at the Age of Peak Bone Mass. Breastfeed Med. 2018; 13 (7): 500-5.
- Yüce T, Kalafat E, Koc A. Adolescent pregnancy; a determinant of bone mineral density in peri-menopausal women? Maturitas. 2015; 82 (2): 203-7.
- Kovacs CS. Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery. Physiol Rev. 2016; 96 (2): 449-547.
- Chan GM, McMurry M, Westover K, Engelbert-Fenton K, Thomas MR. Effects of increased dietary calcium intake upon the calcium and bone mineral status of lactating adolescent and adult women. Am J Clin Nutr. 1987; 46 (2): 319-23.
- Bezerra FF, Mendonça LM, Lobato EC, O'Brien KO, Donangelo CM. Bone mass is recovered from lactation to postweaning in adolescent mothers with low calcium intakes. Am J Clin Nutr. 2004 Nov; 80 (5): 1322-6.
- Wongdee K, Krishnamra N, Charoenphandhu N. Endochondral bone growth, bone calcium accretion, and bone mineral density: how are they related? J Physiol Sci. 2012; 62 (4): 299-307.
- Rizzoli R, Bonjour JP, Ferrari SL. Osteoporosis, genetics and hormones. J Mol Endocrinol. 2001; 26 (2): 79-94.
- Eisman JA. Genetics of osteoporosis. Endocr Rev. 1999 Dec; 20 (6): 788-804.
- Khosla S, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Klee GG, Riggs BL. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab. 1998; 83 (7): 2266-74.
- Özcan H, Oskay Ü. Menopoz döneminde semptom yönetiminde kanıta dayalı uygulamalar. Göztepe Tıp Dergisi, 2013. 28 (4): 157-63.
- Ward KA, Adams JE, Roberts SA, Mughal Z, Seif MW. Postpartum bone status in teenage mothers assessed using peripheral quantitative computed tomography. J Clin Densitom. 2009; 12 (2): 219-23.
- Demir B, Haberal A, Geyik P, et al. Identification of the risk factors for osteoporosis among postmenopausal women. Maturitas. 2008; 60 (3-4): 253-6.
- Kim YM, Hyun NR, Shon HS, et al. Assessment of clinical risk factors to validate the probability of osteoporosis and subsequent fractures in Korean women. Calcif Tissue Int. 2008; 83 (6): 380-7.
Menopoz sonrası kemik yoğunluğu ile ergenlik döneminde gerçekleşen ilk doğum arasındaki ilişkinin araştırılması
Abstract
Amaç: İlk doğum yaşının postmenopozal kemik yoğunluğu ile ilişkisini değerlendirmek.
Gereç ve Yöntem: Rutin yıllık kontrol amacıyla hastanemiz menopoz polikliniğine başvuran ve çalışma koşullarını karşılayan ardışık tüm hastalar bu çalışmaya dahil edildi. Her hastanın obstetrik öyküsü ve demografik özellikleri sorgulanarak ilk doğum yaşları kaydedildi. Vertebra ve femur kemik yoğunluğu dual enerji x ışını absorpsiyometri (DEXA) cihazı ile ölçüldü.
Bulgular: Çalışmaya adölesan doğum öyküsü olan 36, adölesan doğum öyküsü olmayan 44 olmak üzere toplamda 80 hasta dahil edildi. Gruplar arasında yaş, menopoz süresi, çocuk sayısı, aylık gelir, vücut kitle indeksi, menopoz tipi, mesleki durum, eğitim durumu, ilaç kullanımı, obezite açısından istatistiksel olarak anlamlı fark saptanmadı (p>0,05). İki grup arasında ölçülen Lomber T, Lomber Z, femur T ve femur Z skorları arasında istatistiksel olarak anlamlı fark saptandı (p<0,05).
Sonuç: Adölesan yaşta yapılan doğumlar hem femur hem de bel kemik mineral yoğunluğunu pozitif yönde etkileyebilir.
References
- Dehne KL, Riedner G. Adolescence--a dynamic concept. Reprod Health Matters. 2001; 9 (17): 11-5.
- Bryce J, Boschi-Pinto C, Shibuya K, Black RE; WHO Child Health Epidemiology Reference Group. WHO estimates of the causes of death in children. Lancet. 2005; 365 (9465): 1147-52.
- Türkiye İstatistik Kurumu, İl, yaş grubu ve cinsiyete göre nüfus. 2017. [Cited 19 November 2018]. Available from http://www.tuik.gov.tr/PreIstatistikTablo.do?istab_id=945.
- Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, Adölesan Doğurganlık ve Annelik. 2013 Türkiye Nüfus ve Sağlık Araştırması, Ankara, Türkiye, 2014. [Cited 19 November 2018]. Available from: http://www.hips.hacettepe.edu.tr/tnsa2013/rapor/TNSA_2013_ana_rapor.pdf
- Lloyd T, Lin HM, Eggli DF, Dodson WC, Demers LM, Legro RS. Adolescent Caucasian mothers have reduced adult hip bone density. Fertil Steril. 2002; 77 (1): 136-40.
- Ott SM, Scholes D, LaCroix AZ, Ichikawa LE, Yoshida CK, Barlow WE. Effects of contraceptive use on bone biochemical markers in young women. J Clin Endocrinol Metab. 2001; 86 (1): 179-85.
- Loro ML, Sayre J, Roe TF, Goran MI, Kaufman FR, Gilsanz V. Early identification of children predisposed to low peak bone mass and osteoporosis later in life. J Clin Endocrinol Metab. 2000; 85 (10): 3908-18.
- Cho GJ, Shin JH, Yi KW, et al. Adolescent pregnancy is associated with osteoporosis in postmenopausal women. Menopause. 2012; 19 (4): 456-60.
- Teerapornpuntakit J, Chanprapaph P, Charoenphandhu N. Previous Adolescent Pregnancy and Breastfeeding Does Not Negatively Affect Bone Mineral Density at the Age of Peak Bone Mass. Breastfeed Med. 2018; 13 (7): 500-5.
- Yüce T, Kalafat E, Koc A. Adolescent pregnancy; a determinant of bone mineral density in peri-menopausal women? Maturitas. 2015; 82 (2): 203-7.
- Kovacs CS. Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery. Physiol Rev. 2016; 96 (2): 449-547.
- Chan GM, McMurry M, Westover K, Engelbert-Fenton K, Thomas MR. Effects of increased dietary calcium intake upon the calcium and bone mineral status of lactating adolescent and adult women. Am J Clin Nutr. 1987; 46 (2): 319-23.
- Bezerra FF, Mendonça LM, Lobato EC, O'Brien KO, Donangelo CM. Bone mass is recovered from lactation to postweaning in adolescent mothers with low calcium intakes. Am J Clin Nutr. 2004 Nov; 80 (5): 1322-6.
- Wongdee K, Krishnamra N, Charoenphandhu N. Endochondral bone growth, bone calcium accretion, and bone mineral density: how are they related? J Physiol Sci. 2012; 62 (4): 299-307.
- Rizzoli R, Bonjour JP, Ferrari SL. Osteoporosis, genetics and hormones. J Mol Endocrinol. 2001; 26 (2): 79-94.
- Eisman JA. Genetics of osteoporosis. Endocr Rev. 1999 Dec; 20 (6): 788-804.
- Khosla S, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Klee GG, Riggs BL. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab. 1998; 83 (7): 2266-74.
- Özcan H, Oskay Ü. Menopoz döneminde semptom yönetiminde kanıta dayalı uygulamalar. Göztepe Tıp Dergisi, 2013. 28 (4): 157-63.
- Ward KA, Adams JE, Roberts SA, Mughal Z, Seif MW. Postpartum bone status in teenage mothers assessed using peripheral quantitative computed tomography. J Clin Densitom. 2009; 12 (2): 219-23.
- Demir B, Haberal A, Geyik P, et al. Identification of the risk factors for osteoporosis among postmenopausal women. Maturitas. 2008; 60 (3-4): 253-6.
- Kim YM, Hyun NR, Shon HS, et al. Assessment of clinical risk factors to validate the probability of osteoporosis and subsequent fractures in Korean women. Calcif Tissue Int. 2008; 83 (6): 380-7.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | March 13, 2020 |
| Submission Date | November 20, 2018 |
| Published in Issue | Year 2020Volume: 59 Issue: 1 |
