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DIFFERENTIAL DIAGNOSIS OF GENDER DYSPHORIA IN TERMS OF REPRODUCTIVE ENDOCRINOLOGY

Year 2021, Volume: 84 Issue: S-1, 23 - 25, 30.04.2021

Abstract

An increasing number of adolescents and adults present to clinics for medical assistance with gender dysphoria. The first evaluation of the patients presenting with this clinical picture with unclear etiology includes a short clinical examination to exclude various reproductive and endocrinological pathologies that may rarely cause this condition. This review aimed to provide an overview of the differential diagnosis of gender dysphoria in terms of reproductive endocrinology.

References

  • 1. American Psychiatric Association. Gender dysphoria. In: Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, American Psychiatric Association, Arlington, VA 2013. p.451. [CrossRef]
  • 2. Saraswat A, Weinand JD, Safer JD. Evidence supporting the biologic nature of gender identity. Endocr Pract 2015;21:199. [CrossRef]
  • 3. Conron KJ, Scott G, Stowell GS, Landers SJ. Transgender health in Massachusetts: results from a household probability sample of adults. Am J Public Health 2012;102:118. [CrossRef]
  • 4. Reisner SL, Conron KJ, Tardiff LA, et al. Monitoring the health of transgender and other gender minority populations: validity of natal sex and gender identity survey items in a U.S. national cohort of young adults. BMC Public Health 2014;14:1224. [CrossRef]
  • 5. Friedman CI, Schmidt GE, Kim MH, Powell J. Serum testosterone concentrations in the evaluation of androgenproducing tumors. Am J Obstet Gynecol 1985;153:44. [CrossRef]
  • 6. Derksen J, Nagesser SK, Meinders AE, et al. Identification of virilizing adrenal tumors in hirsute women. N Engl J Med 1994;331:968. [CrossRef]
  • 7. Azziz R, Dewailly D, Owerbach D. Clinical review 56: Nonclassic adrenal hyperplasia: current concepts. J Clin Endocrinol Metab 1994;78:810. [CrossRef]
  • 8. Inoubli A, De Cuypere G, Rubens R, Heylens G, Elaut E, Van Caenegem E, Menten B, T’Sjoen G. Karyotyping, is it worthwhile in transsexualism? J Sex Med 2011;8:475-8. [CrossRef]
  • 9. Auer MK, Fuss J, Stalla GK, Athanasoulia AP. Twenty years of endocrinologic treatment in transsexualism: analyzing the role of chromosomal analysis and hormonal profiling in the diagnostic work-up. Fertil Steril 2013;100(4):1103-10. [CrossRef]
  • 10. Fisher AD, Castellini G, Casale H, Fanni E, Bandini E, Campone B, Ferruccio N, Maseroli E, Boddi V, Dèttore D, Pizzocaro A, Balercia G, Oppo A, Ricca V, Maggi M. Hypersexuality, paraphilic behaviors, and gender dysphoria in individuals with Klinefelter’s syndrome. J Sex Med 2015;12:2413-24. [CrossRef]
  • 11. Dessens AB, Slijper FM, Drop SL, Gender dysphoria and gender change in chromosomal females with congenital adrenal hyperplasia. Arch Sex Behav 2005;34(4):389-97. [CrossRef]
  • 12. Lee PA, Nordenström A, Houk CP, et al. Global Disorders of Sex Development Update since 2006: Perceptions, Approach and Care. Horm Res Paediatr 2016;85:158. [CrossRef]
  • 13. Reiner WG, Gearhart JP. Discordant sexual identity in some genetic males with cloacal exstrophy assigned to female sex at birth. N Engl J Med 2004;350:333.
  • [CrossRef] 14. Meyer-Bahlburg HF. Gender identity outcome in femaleraised 46,XY persons with penile agenesis, cloacal exstrophy of the bladder, or penile ablation. Arch Sex Behav 2005;34:423. [CrossRef]

CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI

Year 2021, Volume: 84 Issue: S-1, 23 - 25, 30.04.2021

Abstract

Günümüzde sayıları artmakta olan birçok ergen ve erişkin, cinsiyet hoşnutsuzluğu nedeni ile tıbbi yardım alabilmek üzere kliniklere başvurmaktadır. Etiyolojisi net olarak bilinmeyen bu klinik tablo ile başvuran olguların yapılan ilk değerlendirmesi bu tabloya nadiren neden olabilecek reprodükrtif ve endokrinolojik çeşitli patolojilerin dışlanabilmesi amacıyla yapılan kısa bir klinik değerlendirmeyi içermektedir. Bu derlemede, cinsiyet hoşnutsuzluğunun üreme endokrinolojisi açısından ayırıcı tanısına genel bir bakış sunulması amaçlanmıştır.

References

  • 1. American Psychiatric Association. Gender dysphoria. In: Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, American Psychiatric Association, Arlington, VA 2013. p.451. [CrossRef]
  • 2. Saraswat A, Weinand JD, Safer JD. Evidence supporting the biologic nature of gender identity. Endocr Pract 2015;21:199. [CrossRef]
  • 3. Conron KJ, Scott G, Stowell GS, Landers SJ. Transgender health in Massachusetts: results from a household probability sample of adults. Am J Public Health 2012;102:118. [CrossRef]
  • 4. Reisner SL, Conron KJ, Tardiff LA, et al. Monitoring the health of transgender and other gender minority populations: validity of natal sex and gender identity survey items in a U.S. national cohort of young adults. BMC Public Health 2014;14:1224. [CrossRef]
  • 5. Friedman CI, Schmidt GE, Kim MH, Powell J. Serum testosterone concentrations in the evaluation of androgenproducing tumors. Am J Obstet Gynecol 1985;153:44. [CrossRef]
  • 6. Derksen J, Nagesser SK, Meinders AE, et al. Identification of virilizing adrenal tumors in hirsute women. N Engl J Med 1994;331:968. [CrossRef]
  • 7. Azziz R, Dewailly D, Owerbach D. Clinical review 56: Nonclassic adrenal hyperplasia: current concepts. J Clin Endocrinol Metab 1994;78:810. [CrossRef]
  • 8. Inoubli A, De Cuypere G, Rubens R, Heylens G, Elaut E, Van Caenegem E, Menten B, T’Sjoen G. Karyotyping, is it worthwhile in transsexualism? J Sex Med 2011;8:475-8. [CrossRef]
  • 9. Auer MK, Fuss J, Stalla GK, Athanasoulia AP. Twenty years of endocrinologic treatment in transsexualism: analyzing the role of chromosomal analysis and hormonal profiling in the diagnostic work-up. Fertil Steril 2013;100(4):1103-10. [CrossRef]
  • 10. Fisher AD, Castellini G, Casale H, Fanni E, Bandini E, Campone B, Ferruccio N, Maseroli E, Boddi V, Dèttore D, Pizzocaro A, Balercia G, Oppo A, Ricca V, Maggi M. Hypersexuality, paraphilic behaviors, and gender dysphoria in individuals with Klinefelter’s syndrome. J Sex Med 2015;12:2413-24. [CrossRef]
  • 11. Dessens AB, Slijper FM, Drop SL, Gender dysphoria and gender change in chromosomal females with congenital adrenal hyperplasia. Arch Sex Behav 2005;34(4):389-97. [CrossRef]
  • 12. Lee PA, Nordenström A, Houk CP, et al. Global Disorders of Sex Development Update since 2006: Perceptions, Approach and Care. Horm Res Paediatr 2016;85:158. [CrossRef]
  • 13. Reiner WG, Gearhart JP. Discordant sexual identity in some genetic males with cloacal exstrophy assigned to female sex at birth. N Engl J Med 2004;350:333.
  • [CrossRef] 14. Meyer-Bahlburg HF. Gender identity outcome in femaleraised 46,XY persons with penile agenesis, cloacal exstrophy of the bladder, or penile ablation. Arch Sex Behav 2005;34:423. [CrossRef]
There are 14 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Reviews
Authors

Özlem Dural 0000-0001-7475-9982

Publication Date April 30, 2021
Submission Date April 29, 2020
Published in Issue Year 2021 Volume: 84 Issue: S-1

Cite

APA Dural, Ö. (2021). CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI. Journal of Istanbul Faculty of Medicine, 84(S-1), 23-25.
AMA Dural Ö. CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI. İst Tıp Fak Derg. April 2021;84(S-1):23-25.
Chicago Dural, Özlem. “CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI”. Journal of Istanbul Faculty of Medicine 84, no. S-1 (April 2021): 23-25.
EndNote Dural Ö (April 1, 2021) CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI. Journal of Istanbul Faculty of Medicine 84 S-1 23–25.
IEEE Ö. Dural, “CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI”, İst Tıp Fak Derg, vol. 84, no. S-1, pp. 23–25, 2021.
ISNAD Dural, Özlem. “CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI”. Journal of Istanbul Faculty of Medicine 84/S-1 (April 2021), 23-25.
JAMA Dural Ö. CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI. İst Tıp Fak Derg. 2021;84:23–25.
MLA Dural, Özlem. “CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI”. Journal of Istanbul Faculty of Medicine, vol. 84, no. S-1, 2021, pp. 23-25.
Vancouver Dural Ö. CİNSİYET HOŞNUTSUZLUĞUNUN ÜREME ENDOKRİNOLOJİSİ AÇISINDAN AYIRICI TANISI. İst Tıp Fak Derg. 2021;84(S-1):23-5.

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