Clinical Research
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Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates

Year 2023, Volume: 2 Issue: 3, 117 - 121, 25.09.2023

Merve Ayık Türk Yasemin Özdoğan Özgür Batum Gülru Polat Ufuk Yılmaz

https://doi.org/10.57221/izmirtip.1260544

Abstract

Amaç: Epilepsi, pnömoni, gastrit, özofajit, malnütrisyon, dehidrasyon, kırıklar ve pnömoni dışı akciğer hastalıkları (astım, plevral sıvı, solunum yetmezliği) serebral palsili (SP) hastaların hastaneye yatış nedenlerinin başında gelmektedir. Bu çalışmada göğüs hastalıkları hastanesine başvuran SP'li hastalarda solunum yolu hastalıkları ve mortalite oranlarının belirlenmesi amaçlandı.
Gereç ve Yöntem: Ocak 2010-Aralık 2017 tarihleri arasında Göğüs Hastalıkları Hastanesinde yatan SP'li hastalar çalışmaya dahil edilerek retrospektif olarak incelendi. Çalışmanın primer sonlanım noktası hastanede yatan hastaların solunum yolu enfeksiyonuna bağlı 30 günlük mortalitesiydi.
Bulgular: 23 hastaya ait 43 yatış değerlendirildi. Ortalama hastanede kalış süresi 15,5 (1-62) gündü. SP'li hastalarda hastaneye yatış nedenleri ağırlıklı olarak solunum yolu enfeksiyonlarıydı (pnömoni %88,4, akciğer apsesi %7). En sık izole edilen patojen mikroorganizma gram-negatif bakterilerdi. Hırıltılı solunum, bakteri kültüründe üreme varlığı, vazopressör ihtiyacı ve invaziv mekanik ventilasyon 30 günlük mortaliteyi artıran faktörlerdi (sırasıyla p=0,016; p=0,024; p=0,003; p=0,003). 30 günlük mortalite oranı %21,7 idi. 2 hasta ilk yatışta öldü, 4 hasta tekrarlayan yatışlarda öldü.
Sonuç: SP'li hastalar sıklıkla solunum yolu enfeksiyonları nedeniyle hastaneye yatırılmaktadır. Tekrarlayan hastaneye yatışlar mortaliteyi artırabilir. Bu çalışma, solunum yolu enfeksiyonu nedeniyle hastaneye yatan SP'li hastalardaki yüksek mortalite oranı göz önüne alındığında, bu hastaların yakın takibinin önemini vurgulamaktadır.

Keywords

serebral palsi 30 günlük mortalite göğüs hastalıkları

Supporting Institution

Yok

Project Number

Yok

Thanks

yok

References

  • References 1.B. Hüner, MH Özgüzel, H. Telli, G. Sarı. Polikliniğimize başvuran serebral palsili hastaların klinik ve demografik özellikleri. Okmeydanı Tıp Dergisi 2011;27(1):28-32
  • 2.Odding E, Roebroeck ME, Stam HJ. The epidemiology of cerebral palsy: Incidence, impairments and risk factors. Disabil Rehabil 2006;28(4):183-91
  • 3.Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Dan B, et al. Proposed definition and classification of cerebral palsy. Dev Med Child Neurol 2005;47:571-6.
  • 4.Young NL, McCormick AM, Gilbert T, Ayling-Campos A, Burke T, Fehlings D, et al. Reasons for hospital admissions among youth and young adults with cerebral palsy. Arch Phys Med Rehabil.2011;92(1):46-50.
  • 5.Marpole R, Blackmore AM, Gibson N, Cooper MS, Langdon K, Wilson AC. Evaluation and management of respiratory ıllness in children with cerebral palsy. Front Pediatr. 2020 Jun 24;8:333.
  • 6.Ryan JM, Peterson MD, Ryan N, Smith KJ, O'connell NE, Liverani S, et al. Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy. Dev Med Child Neurol. 2019;61:924–8.
  • 7.Mahon M, Kibirige MS. Patterns of admissions for children with special needs to the paediatric assessment unit. Arch Dis Child 2004;89(2):165-9.
  • 8.Somer; M. Hacımustafaoğlu. Pediatride alt solunum yolu infeksiyonlarında sorunlar. ANKEM Derg 2010;24(2):96-101.
  • 9.Sivak ED, Shefner JM, Sexton J. Neuromuscular disease and hypoventilation. CurrOpinPulmMed. 1999;5(6):355-62.
  • 10.Mehta S. Neuromuscular disease causing acute respiratory failure. RespirCare. 2006;51(9):1016-21.
  • 11.Krigger KW. Cerebral palsy: an overview. Am FamPhysician. 2006 Jan 1;73(1):91-100.
  • 12.Prastiya G, Risky VP, Mira I, Retno AS, Darto S, Erny P. Risk factor of mortality in Indonesian children with cerebral palsy. J MedInvest 2018;65(1.2):18-20.
  • 13.Ryan JM, Peterson MD, Ryan N, Smith KJ, O'connell NE, Liverani S, et al. Mortality due to cardiovascular disease, respiratory disease and cancer in adults with cerebral palsy. Dev Med Child Neurol. 2019;61(8):924-28.
  • 14.Gerdung CA, Tsang a, Yasseen A. Association between chronic aspiration and chronic airway infection with pseudomonas aeruginosa and other gram-negative bacteria in children with cerebral palsy. Lung 2016;194(2):307-14.
  • 15.Ryan JM, Allen E, Gormley J, Hurvitz HA, Peterson MD. The risk, burden, and management of non-communicable diseases in cerebral palsy: a scoping review. Dev Med Child Neurol. 2018;60(8):753-64.

Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir

Year 2023, Volume: 2 Issue: 3, 117 - 121, 25.09.2023

Merve Ayık Türk Yasemin Özdoğan Özgür Batum Gülru Polat Ufuk Yılmaz

https://doi.org/10.57221/izmirtip.1260544

Abstract

Objective: Epilepsy, pneumonia, gastritis, esophagitis, malnutrition, dehydration, fractures, and non-pneumonic lung disorders (asthma, pleural fluid, respiratory failure) are the leading causes of hospitalization among cerebral palsy (CP) patients. This study aimed to determine respiratory tract diseases and mortality rates in patients with CP admitted to the chest diseases hospital.
Materials and Methods: Patients diagnosed with CP and hospitalized in Chest Diseases Hospital between January 2010 and December 2017 were included in the study and analyzed retrospectively. As the endpoint, hospitalized patients' respiratory tract infection-related 30-days mortality were examined.
Results: Forty-three hospitalizations of 23 patients were evaluated. The mean length of hospital stay was 15.5 (1-62) days. The reasons for hospitalization in patients with CP were mainly composed of respiratory tract infections (pneumonia %88,4, lung abscess %7). The most frequently isolated pathogenic microorganisms were gram-negative bacteria. Wheezing, bacterial culture growth, vasopressor and invasive mechanical ventilation were all factors that increased 30-day mortality (respectively p=0,016; p=0,024; p=0,003; p=0,003). The 30-day mortality rate was %21,7. While 2 patients died at first hospitalization, 4 patients died on recurrent hospitalizations.
Conclusion: Patients with CP are often hospitalized due to respiratory tract infections. Recurrent hospitalizations may increase mortality. This study emphasizes the importance of close follow-up with these patients considering the high mortality rate among CP patients hospitalized for respiratory tract infections.

Keywords

cerebral palsy 30 days mortaliy chest disease

Project Number

Yok

References

  • References 1.B. Hüner, MH Özgüzel, H. Telli, G. Sarı. Polikliniğimize başvuran serebral palsili hastaların klinik ve demografik özellikleri. Okmeydanı Tıp Dergisi 2011;27(1):28-32
  • 2.Odding E, Roebroeck ME, Stam HJ. The epidemiology of cerebral palsy: Incidence, impairments and risk factors. Disabil Rehabil 2006;28(4):183-91
  • 3.Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Dan B, et al. Proposed definition and classification of cerebral palsy. Dev Med Child Neurol 2005;47:571-6.
  • 4.Young NL, McCormick AM, Gilbert T, Ayling-Campos A, Burke T, Fehlings D, et al. Reasons for hospital admissions among youth and young adults with cerebral palsy. Arch Phys Med Rehabil.2011;92(1):46-50.
  • 5.Marpole R, Blackmore AM, Gibson N, Cooper MS, Langdon K, Wilson AC. Evaluation and management of respiratory ıllness in children with cerebral palsy. Front Pediatr. 2020 Jun 24;8:333.
  • 6.Ryan JM, Peterson MD, Ryan N, Smith KJ, O'connell NE, Liverani S, et al. Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy. Dev Med Child Neurol. 2019;61:924–8.
  • 7.Mahon M, Kibirige MS. Patterns of admissions for children with special needs to the paediatric assessment unit. Arch Dis Child 2004;89(2):165-9.
  • 8.Somer; M. Hacımustafaoğlu. Pediatride alt solunum yolu infeksiyonlarında sorunlar. ANKEM Derg 2010;24(2):96-101.
  • 9.Sivak ED, Shefner JM, Sexton J. Neuromuscular disease and hypoventilation. CurrOpinPulmMed. 1999;5(6):355-62.
  • 10.Mehta S. Neuromuscular disease causing acute respiratory failure. RespirCare. 2006;51(9):1016-21.
  • 11.Krigger KW. Cerebral palsy: an overview. Am FamPhysician. 2006 Jan 1;73(1):91-100.
  • 12.Prastiya G, Risky VP, Mira I, Retno AS, Darto S, Erny P. Risk factor of mortality in Indonesian children with cerebral palsy. J MedInvest 2018;65(1.2):18-20.
  • 13.Ryan JM, Peterson MD, Ryan N, Smith KJ, O'connell NE, Liverani S, et al. Mortality due to cardiovascular disease, respiratory disease and cancer in adults with cerebral palsy. Dev Med Child Neurol. 2019;61(8):924-28.
  • 14.Gerdung CA, Tsang a, Yasseen A. Association between chronic aspiration and chronic airway infection with pseudomonas aeruginosa and other gram-negative bacteria in children with cerebral palsy. Lung 2016;194(2):307-14.
  • 15.Ryan JM, Allen E, Gormley J, Hurvitz HA, Peterson MD. The risk, burden, and management of non-communicable diseases in cerebral palsy: a scoping review. Dev Med Child Neurol. 2018;60(8):753-64.
There are 15 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Articles
Authors

Merve Ayık Türk 0000-0003-3106-7403

Yasemin Özdoğan 0000-0003-2693-9756

Özgür Batum 0000-0002-8353-3421

Gülru Polat 0000-0002-2211-1268

Ufuk Yılmaz 0000-0001-6406-9355

Project Number Yok
Publication Date September 25, 2023
Submission Date March 5, 2023
Published in Issue Year 2023 Volume: 2 Issue: 3

Cite

APA Ayık Türk, M., Özdoğan, Y., Batum, Ö., Polat, G., et al. (2023). Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir. İzmir Tıp Fakültesi Dergisi, 2(3), 117-121. https://doi.org/10.57221/izmirtip.1260544
AMA Ayık Türk M, Özdoğan Y, Batum Ö, Polat G, Yılmaz U. Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir. İzmir Tıp Fak. Derg. September 2023;2(3):117-121. doi:10.57221/izmirtip.1260544
Chicago Ayık Türk, Merve, Yasemin Özdoğan, Özgür Batum, Gülru Polat, and Ufuk Yılmaz. “Patients With Cerebral Palsy Who Are Admitted to a Chest Diseases Hospital May Have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir”. İzmir Tıp Fakültesi Dergisi 2, no. 3 (September 2023): 117-21. https://doi.org/10.57221/izmirtip.1260544.
EndNote Ayık Türk M, Özdoğan Y, Batum Ö, Polat G, Yılmaz U (September 1, 2023) Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir. İzmir Tıp Fakültesi Dergisi 2 3 117–121.
IEEE M. Ayık Türk, Y. Özdoğan, Ö. Batum, G. Polat, and U. Yılmaz, “Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir”, İzmir Tıp Fak. Derg., vol. 2, no. 3, pp. 117–121, 2023, doi: 10.57221/izmirtip.1260544.
ISNAD Ayık Türk, Merve et al. “Patients With Cerebral Palsy Who Are Admitted to a Chest Diseases Hospital May Have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir”. İzmir Tıp Fakültesi Dergisi 2/3 (September 2023), 117-121. https://doi.org/10.57221/izmirtip.1260544.
JAMA Ayık Türk M, Özdoğan Y, Batum Ö, Polat G, Yılmaz U. Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir. İzmir Tıp Fak. Derg. 2023;2:117–121.
MLA Ayık Türk, Merve et al. “Patients With Cerebral Palsy Who Are Admitted to a Chest Diseases Hospital May Have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir”. İzmir Tıp Fakültesi Dergisi, vol. 2, no. 3, 2023, pp. 117-21, doi:10.57221/izmirtip.1260544.
Vancouver Ayık Türk M, Özdoğan Y, Batum Ö, Polat G, Yılmaz U. Patients with Cerebral Palsy Who are Admitted to a Chest Diseases Hospital may have Higher Mortality Rates Serebral Palsili Hastaların Göğüs Hastalıkları Hastanesine Yatışları Mortal Seyredebilir. İzmir Tıp Fak. Derg. 2023;2(3):117-21.
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