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Year 2020, Volume: 10 Issue: 4, 481 - 486, 30.12.2020
https://doi.org/10.16899/jcm.776695

Abstract

Supporting Institution

yok

Project Number

yok

References

  • Referans 1.4. Hwang JA, Kim YS, Leem AY, et al. Clinical implications of sarcopenia on decreased bone density in men with COPD. Chest 2017; 151: 1018-1027.
  • Referans 2. 10. Imtiaz F, Shafique K, Mirza SS, Ayoob Z, Vart P, Rao S. Neutrophil Lymphocyte Ratio as a Measure of Systemic Inflammation in Prevalent Chronic Diseases in Asian Population. Int Arch Med 2012; 5(1): 2.

Can neutrophil-lymphocyte ratio and platelet-lymphocyte ratio be related with skeletal mass area in COPD patients with acute exacerbation?

Year 2020, Volume: 10 Issue: 4, 481 - 486, 30.12.2020
https://doi.org/10.16899/jcm.776695

Abstract

Introduction:This study was designed to assess whether there is a relation between inflammatory biomarkers such as NLR, PLR and psoas muscle area (PMA) as a marker of sarcopenia in COPD pateints who admitted to the emergency department of our clinic. Method: Retrospectivly one hundred forty three COPD patients who had CT scan for any reason during hospital admission were included. Patient characteristics and clinical and laboratory data were evaluated retrospectively. Results:In our study, we performed the correlations between NLR, PLR and CRP, FEV1, FVC, FEV1/FVC, right PMA, left PMA, total PMA. NLR and PLR were positively correlated with CRP (r=0.60, p<0.001, r=0.37, p<0.001, respectively), and no correlation was observed between NLR, PLR, CRP and all PMA values. However, there was a positive correlation between all PMA values and FEV1, FEV1/FVC parameters. There was no correlation between sarcopenia and emergency admission frequency and mortality. Conclusion NLR, and PLR may have a role as a biomarker of inflammation in COPD and its exacerbation. Sarcopenia is an expected finding in COPD patients, but relation between sarcopenia and inflammation requires further investigation.

Project Number

yok

References

  • Referans 1.4. Hwang JA, Kim YS, Leem AY, et al. Clinical implications of sarcopenia on decreased bone density in men with COPD. Chest 2017; 151: 1018-1027.
  • Referans 2. 10. Imtiaz F, Shafique K, Mirza SS, Ayoob Z, Vart P, Rao S. Neutrophil Lymphocyte Ratio as a Measure of Systemic Inflammation in Prevalent Chronic Diseases in Asian Population. Int Arch Med 2012; 5(1): 2.
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Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Research
Authors

Sibel Yurt 0000-0002-7703-110X

Lale Tuna 0000-0003-4409-3459

Halit Çınarka This is me 0000-0002-4910-149X

Mehmet Toptaş 0000-0002-3118-8793

Kemal Karapınar This is me 0000-0002-0035-5325

Gamze Kırkıl This is me 0000-0003-4799-5589

Project Number yok
Publication Date December 30, 2020
Acceptance Date September 11, 2020
Published in Issue Year 2020 Volume: 10 Issue: 4

Cite

AMA Yurt S, Tuna L, Çınarka H, Toptaş M, Karapınar K, Kırkıl G. Can neutrophil-lymphocyte ratio and platelet-lymphocyte ratio be related with skeletal mass area in COPD patients with acute exacerbation?. J Contemp Med. December 2020;10(4):481-486. doi:10.16899/jcm.776695