Abstract
Coronavirüs Hastalığı 2019 (COVID-19) viral kaynaklı bir pandemidir. Hastalığın olumsuz gebelik sonuçlarıyla doğrudan ilişkili olmadığı savunulmakla birlikte, çalışmalarda COVID-19'lu gebeliklerde fetal distres oarnının arttığı gösterilmiştir. Bu vaka serisinde, asemptomatik COVID-19'un eşlik ettiği fetal taşikardi vakalarını sunmayı amaçladık. Bu çalışmada, rutin gebelik takibi için başvuran ve termed gebeliği olan 3 hastada, fetal taşikardi temelinde fetal distres geliştiği tespit edildi ve acil sezaryen ile doğum gerçekleştirildi. Gebelerden hiçbirinin kronik hastalığı veya COVID-19’lu bir vaka ile yakın temas öyküsü yoktu. Tam kan sayımı ve kan serumu analizleri normaldi. Tüm hastalara asemptomatik COVID-19 teşhisi konuldu ve yenidoğanlardan 1 tanesinde de COVID-19 pozitif çıktı. Bu doğrultuda, fetal taşikardi tespit edilen gebeliklerde, hastalık semptomları olmasa bile COVID-19 ihtimali akılda tutulmalıdır. Fetal distres, obstetrik bir acildir. Bu nedenle olası olumsuz maternal ve neonatal sonuçlarla başa çıkabilmek için COVID-19'un potansiyel tehditleri göz önünde bulundurulmalıdır.
References
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- 12. Zamaniyan M, Ebadi A, Aghajanpoor S, Rahmani Z, Haghshenas M, Azizi S. Preterm delivery, maternal death, and vertical transmission in a pregnant woman with COVID-19 infection. Prenat Diagn. 2020;40(13):1759-1761.
Abstract
Coronavirus Disease 2019(COVID-19)pandemics is a novel viral infection.The disease was not found as directly related with adverse pregnancy outcomes;however,the incidence of fetal distress has shown to be increased in pregnancies with COVID-19.This case series aimed to present fetal tachycardia cases with accompanying asymptomatic COVID-19.This study reported three women with term pregnancies applied for routine pregnancy follow-up were detected to develop fetal distress at the basis of fetal tachycardia and delivered through emergency C-section.None of them had any chronic disease or the history of close contact.The complete blood count and blood serum analyses were normal.All patients were diagnosed to have asymptomatic COVID-19,of which one neonate was positive for COVID-19. COVID-19 should be considered in fetal tachycardia cases, even in the absence of disease symptoms.Fetal distress is an obstetric emergency;therefore,the potential threats of COVID-19 should be kept in mind to be able to cope with possible adverse maternal and neonatal outcomes.
References
- 1. Yang Z, Wang M, Zhu Z, Liu Y. Coronavirus disease 2019 (COVID-19) and pregnancy: a systematic review. J Matern Fetal Neonatal Med. 2020:1-4.
- 2. Gravett C, Eckert LO, Gravett MG, Dudley DJ, Stringer EM, Mujobu TB, et al. Non-reassuring fetal status: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine. 2016;34(49):6084-92.
- 3. Erol Koc EM, Findik RB, Akkaya H, Karadag I, Tokalıoğlu EO, Tekin OM. Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort. J Perinat Med. 2020;49(2):141-147.
- 4. Ashraf MA, Keshavarz P, Hosseinpour P, Erfani A, Roshanshad A, Pourdast A, et al. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Pregnancy and the Possibility of Vertical Transmission. J Reprod Infertil. 2020;21(3):157-68.
- 5. Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9(1):51-60.
- 6. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809-15.
- 7. Ducsay CA, Goyal R, Pearce WJ, Wilson S, Hu XQ, Zhang L. Gestational Hypoxia and Developmental Plasticity. Physiol Rev. 2018;98(3):1241-334.
- 8. Ng WF, Wong SF, Lam A, Mak YF, Yao H, Lee KC, et al. The placentas of patients with severe acute respiratory syndrome: a pathophysiological evaluation. Pathology. 2006;38(3):210-8.
- 9. Schoenmakers S, Snijder P, Verdijk R, Kuiken T, Kamphuis S, Koopman L, et al. SARS-CoV-2 placental infection and inflammation leading to fetal distress and neonatal multi-organ failure in an asymptomatic woman. J Pediatric Infect Dis Soc. 2021;10(5):556-561.
- 10. Sharps MC, Hayes DJL, Lee S, Zou Z, Brady CA, Almoghrabi Y, et al. A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection. Placenta. 2020;101:13-29.
- 11. Li M, Chen L, Zhang J, Xiong C, Li X. The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study. PLoS One. 2020;15(4):e0230295.
- 12. Zamaniyan M, Ebadi A, Aghajanpoor S, Rahmani Z, Haghshenas M, Azizi S. Preterm delivery, maternal death, and vertical transmission in a pregnant woman with COVID-19 infection. Prenat Diagn. 2020;40(13):1759-1761.
Details
| Primary Language | English |
|---|---|
| Subjects | Obstetrics and Gynaecology |
| Journal Section | Case Reports |
| Authors | |
| Publication Date | March 30, 2023 |
| Submission Date | February 21, 2022 |
| Acceptance Date | July 17, 2022 |
| Published in Issue | Year 2023 Volume: 20 Issue: 1 |
