Abstract
The spermatocytic seminoma is a different testicular
germ cell neoplasm representing less than 1% of testicular cancers. It has
distinctive clinical and pathological features when compared with classical
seminoma. Diagnosis of spermatocytic seminoma is difficult, especially in
elderly patients, due to its rare occurrence, lack of clinical presentation,
and the difficulty of differential diagnosis with morphologically testicular
lymphoma and classical seminoma. Here we present the clinical presentation,
histopathologic features and prognosis of a spermatocytic seminoma case in the
light of literature information.
References
- 1. Talerman A: Spermatocytic seminoma: clinicopathological study of 22 cases. Cancer 1980, 15:2169–2176.
- 2. Rosai J, Nochomovitz LE: Current concepts of the histogenesis, pathology, and immunocytochemistry of germ cell tumors of the testis. Parhol Annu 1978, 13:335–338.
- 3. Floyd C, Ayala AG, Logothetis CJ, Silva EG: Spermatocytic seminoma with associated sarcoma of the testis. Cancer 1988, 15:409–414.
- 4. Carrière P, Baade P, Fritschi L: Population based incidence and age distribution of spermatocytic seminoma. J Urol 2007, 178:125–128.
- 5. Masson P: A study of seminomas. Rev Cunud B id 1946,5:361–387.
- 6. Dundr P, Pesl M, Povýsil C, Prokopová P, Pavlík I, Soukup V, Dvorácek J: Anaplastic variant of spermatocytic seminoma. Pathol Res Pract 2007, 203:621–624.
- 7. Chelly I, Mekni A, Gargouri MM, Bellil K, Zitouna M, Horchani A, Kchir N: Spermatocytic seminoma with rhabdomyosarcomatous contigent. Prog Urol 2006, 16:218-220.
- 8.Rosai J, Silber I, Khodadoust K: Spermatocytic seminoma. Clinicopathologic study of six cases and review of the literature. Cancer 1969, 24:92-102.
- 9. Burke AP, Mostofi FK: Spermatocytic seminoma: a clinicopathololgic studyof 79 cases. J Urol Pathol 1993, 1:21-32.
- 10. Carrière P, Peter B, Lin F: From the Viertel Centre for Research in Cancer Control, Brisbane, Queensland (PC, PB), and WesternAustralian Institute for Medical Research, Perth (LF), Australia.
- 11. Van Gurp R, De Krijger R, Geurts Van Kessel A, Köberle B, Oosterhuis Stoop W, Looijenga L: Reactivity of germ cell maturation stagespecific markers in spermatocytic seminoma: diagnostic and etiological implications. Lab Invest 2001, 81:919–928.
- 12. Looijenga LH, Hersmus R, Gillis AJ, Pfundt R, Stoop HJ, Van Gurp RJ et al. Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Res 2006, 66:290–302.
- 13. Chung PW, Bayley AJ, Sweet J, Jewett MA, Tew-George B, Gospodarowicz MK,Warde PR: Spermatocytic seminoma: a review. Eur Urol 2004, 45:495–498
- 14. Raiss GG, Benatiya Andaloussi MM, Raissouni SS, Mrabti HH, Errihani HH: Spermatocytic seminoma at the national institute of oncology in Morocco. BMC Res Notes 2011, 29(4):218.
- 15. Oosterhuis JW, Looijenga LH: Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 2005, 5:210–222.
- 16. Cummings OW, Ulbright TM, Eble JN, et al: Spermatocytic seminoma: animmunohistochemical study. Hum Pathol 1994, 25:54-59.
- 17. Albores-Saavedra J, Huffman H, Alvarado-Cabrero I, Ayala AG: Anaplasticvariant of spermatocytic seminoma. Hum Pathol 1996, 27:650-655.
- 18. Steiner H, Gozzi C, Verdorfer I, Mikuz G, Bartsch G, Hobisch A: Metastaticspermatocytic seminoma - an extremely rare disease. Eur Urol 2006,49:183-186.
- 19. Trivedi P, Pasricha S, Gupta A: Spermatocytic seminoma associated withundifferentiated sarcoma: a rare case report. Indian J Pathol Microbiol2011, 54:138-140.
- 20. Narang V, Gupta K, Gupta A, Kumar S: Rhabdomyosarcomatous differentiation in a spermatocytic seminoma with review of literature. Indian J Urol 2012, 28:430–433.
Abstract
Spermatocytic
seminom, testiküler kanserlerin %1'inden azını temsil eden farklı bir
testiküler germ hücreli neoplazmdır. Klasik seminomla karşılaştırıldığında
belirgin klinik ve patolojik özelliklere sahiptir. Spermatocytic seminom
tanısı, özellikle yaşlı hastalarda, nadir görülmesi, klinik prezentasyonun
olmaması ve morfolojik testiküler lenfoma ve klasik seminom ile ayırıcı tanıda
zorluğundan dolayı zordur. Burada literatür bilgileri ışığında bir
spermatocytic seminom vakasının klinik prezentasyonu, histopatolojik
özellikleri ve prognozunu sunuyoruz.
References
- 1. Talerman A: Spermatocytic seminoma: clinicopathological study of 22 cases. Cancer 1980, 15:2169–2176.
- 2. Rosai J, Nochomovitz LE: Current concepts of the histogenesis, pathology, and immunocytochemistry of germ cell tumors of the testis. Parhol Annu 1978, 13:335–338.
- 3. Floyd C, Ayala AG, Logothetis CJ, Silva EG: Spermatocytic seminoma with associated sarcoma of the testis. Cancer 1988, 15:409–414.
- 4. Carrière P, Baade P, Fritschi L: Population based incidence and age distribution of spermatocytic seminoma. J Urol 2007, 178:125–128.
- 5. Masson P: A study of seminomas. Rev Cunud B id 1946,5:361–387.
- 6. Dundr P, Pesl M, Povýsil C, Prokopová P, Pavlík I, Soukup V, Dvorácek J: Anaplastic variant of spermatocytic seminoma. Pathol Res Pract 2007, 203:621–624.
- 7. Chelly I, Mekni A, Gargouri MM, Bellil K, Zitouna M, Horchani A, Kchir N: Spermatocytic seminoma with rhabdomyosarcomatous contigent. Prog Urol 2006, 16:218-220.
- 8.Rosai J, Silber I, Khodadoust K: Spermatocytic seminoma. Clinicopathologic study of six cases and review of the literature. Cancer 1969, 24:92-102.
- 9. Burke AP, Mostofi FK: Spermatocytic seminoma: a clinicopathololgic studyof 79 cases. J Urol Pathol 1993, 1:21-32.
- 10. Carrière P, Peter B, Lin F: From the Viertel Centre for Research in Cancer Control, Brisbane, Queensland (PC, PB), and WesternAustralian Institute for Medical Research, Perth (LF), Australia.
- 11. Van Gurp R, De Krijger R, Geurts Van Kessel A, Köberle B, Oosterhuis Stoop W, Looijenga L: Reactivity of germ cell maturation stagespecific markers in spermatocytic seminoma: diagnostic and etiological implications. Lab Invest 2001, 81:919–928.
- 12. Looijenga LH, Hersmus R, Gillis AJ, Pfundt R, Stoop HJ, Van Gurp RJ et al. Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Res 2006, 66:290–302.
- 13. Chung PW, Bayley AJ, Sweet J, Jewett MA, Tew-George B, Gospodarowicz MK,Warde PR: Spermatocytic seminoma: a review. Eur Urol 2004, 45:495–498
- 14. Raiss GG, Benatiya Andaloussi MM, Raissouni SS, Mrabti HH, Errihani HH: Spermatocytic seminoma at the national institute of oncology in Morocco. BMC Res Notes 2011, 29(4):218.
- 15. Oosterhuis JW, Looijenga LH: Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 2005, 5:210–222.
- 16. Cummings OW, Ulbright TM, Eble JN, et al: Spermatocytic seminoma: animmunohistochemical study. Hum Pathol 1994, 25:54-59.
- 17. Albores-Saavedra J, Huffman H, Alvarado-Cabrero I, Ayala AG: Anaplasticvariant of spermatocytic seminoma. Hum Pathol 1996, 27:650-655.
- 18. Steiner H, Gozzi C, Verdorfer I, Mikuz G, Bartsch G, Hobisch A: Metastaticspermatocytic seminoma - an extremely rare disease. Eur Urol 2006,49:183-186.
- 19. Trivedi P, Pasricha S, Gupta A: Spermatocytic seminoma associated withundifferentiated sarcoma: a rare case report. Indian J Pathol Microbiol2011, 54:138-140.
- 20. Narang V, Gupta K, Gupta A, Kumar S: Rhabdomyosarcomatous differentiation in a spermatocytic seminoma with review of literature. Indian J Urol 2012, 28:430–433.
Details
| Primary Language | English |
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| Subjects | Health Care Administration |
| Journal Section | Case Report |
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| Publication Date | September 22, 2019 |
| Published in Issue | Year 2019 Volume: 2 Issue: 4 |
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