Research Article
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Year 2021, Volume: 5 Issue: 8, 780 - 784, 01.08.2021
https://doi.org/10.28982/josam.957145

Abstract

References

  • 1. As AK, Engin M, Türk T. Early-term results of early coronary artery bypass graft surgery in patients undergoing primary percutaneous coronary intervention due to acute coronary syndrome. Eur Res J. 2020;7(1):59-65.
  • 2. Abanoz M, Engin M. The effect of the relationship between post-cardiotomy neutrophil/lymphocyte ratio and platelet counts on early major adverse events after isolated coronary artery bypass grafting. Turk Gogus Kalp Damar Cerrahisi Derg. 2021 Jan 13;29(1):36-44.
  • 3. Engin M, Ozsin KK, Savran M, Guvenc O, Ozyazicioglu AF. Visceral Adiposity Index and Prognostic Nutritional Index in Predicting Atrial Fibrillation after On-Pump Coronary Artery Bypass Operations: a Prospective Study. Braz J Cardiovasc Surg. 2020 Dec 23. doi: 10.21470/1678-9741-2020-0044.
  • 4. Ozturk S, Kalyoncuoglu M, Sahin M. Comparison of SYNTAX Score I and SYNTAX Score II for Predicting Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Graft Surgery. Heart Surg Forum 2019;22(5):E319-E324.
  • 5. Erdolu B, As AK, Engin M. The Relationship between the HATCH Score, Neutrophil to Lymphocyte Ratio and Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Graft Surgery. Heart Surg Forum. 2020 Feb 27;23(1):E088-E092.
  • 6. Şahinalp Ş, Çeviker K, Soyal MFT, Gür AK. Retrospective evaluation of ultrafiltration during cardiac surgery with cardiopulmonary bypass in adult patients with increased neutrophil to lymphocyte ratio. J Surg Med. 2020;4(12):1209-14.
  • 7. Çayır MÇ, Til A. The utility of mean platelet volume as a predictor of postoperative atrial fibrillation following coronary artery bypass grafting. J Surg Med. 2020;4(6):438-42.
  • 8. Weymann A, Ali-Hasan-Al-Saegh S, Popov AF, Sabashnikov A, Mirhosseini SJ, Liu T, et al. Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis. Kardiol Pol. 2018;76(1):107-18.
  • 9. Echahidi N, Pibarot P, O’Hara G, Mathieu P. Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery. J Am Coll Cardiol. 2008;51(8):793–801.
  • 10. Martin JF, Shaw T, Heggie J, Penington DG. Measurement of the density of human platelets and its relationship to volume. Br J Haematol. 1983 Jul;54(3):337-52.
  • 11. Akgül E, Engin M, Özyazıcıoğlu AF. Effects of mean platelet volume and platelet counts on peripheral biodegradable stent restenosis. J Surg Med. 2019;3(9):663-5. 12. Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD. Mean platelet volume: a link between thrombosis and inflammation? Curr Pharm Des. 2011;17(1):47-58.
  • 12. Venkatraghavan L, Tan TP, Mehta J, Arekapudi A, Govindarajulu A, Siu E. Neutrophil Lymphocyte Ratio as a predictor of systemic inflammation - A cross-sectional study in a pre-admission setting. F1000Res. 2015 May 22;4:123.
  • 13. Erdem K, Ayhan S, Ozturk S, Bugra O, Bozoglan O, Dursin H, Yazici M, Daglar B. Usefulness of the mean platelet volume for predicting new-onset atrial fibrillation after isolated coronary artery bypass grafting. Platelets. 2014;25(1):23-6.
  • 14. Pala AA, Urcun YS. Is the Mean Platelet Volume a Predictive Factor for Atrial Fibrillation Developing After Coronary Artery Bypass Grafting in Elderly Patients? Heart Surg Forum. 2020 Nov 2;23(6):E809-E814.
  • 15. Berkovitch A, Younis A, Grossman Y, Segev S, Kivity S, Sidi Y, Beinart R, Goldenberg I, Maor E. Relation of Neutrophil to Lymphocyte Ratio to Risk of Incident Atrial Fibrillation. Am J Cardiol. 2019 Feb 1;123(3):396-401.
  • 16. Shao Q, Chen K, Rha SW, Lim HE, Li G, Liu T. Usefulness of Neutrophil/Lymphocyte Ratio as a Predictor of Atrial Fibrillation: A Meta-analysis. Arch Med Res. 2015 Apr;46(3):199-206.
  • 17. Liu Z, Nguyen Khuong J, Borg Caruana C, Jackson SM, Campbell R, Ramson DM, et al. The Prognostic Value of Elevated Perioperative Neutrophil-Lymphocyte Ratio in Predicting Postoperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-Analysis. Heart Lung Circ. 2020 Jul;29(7):1015-24.
  • 18. Hudzik B, Szkodziński J, Lekston A, Gierlotka M, Poloński L, Gąsior M. Mean platelet volume-to-lymphocyte ratio: a novel marker of poor short- and long-term prognosis in patients with diabetes mellitus and acute myocardial infarction. J Diabetes Complications. 2016 Aug;30(6):1097-102.
  • 19. Chen SY, Lin YS, Cheng YF, Wang H, Niu XT, Zhang WL. Mean Platelet Volume-To-Lymphocyte Ratio Predicts Poor Functional Outcomes Among Ischemic Stroke Patients Treated With Intravenous Thrombolysis. Front Neurol. 2019 Dec 10;10:1274.
  • 20. Erdolu B, Engin M. The effect of mean platelet volume-to-lymphocyte ratio on symptom onset in patients with carotid artery stenosis. Turk J Vasc Surg 2021;30(1):7-12.
  • 21. Echahidi N, Pibarot P, O'Hara G, Mathieu P. Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery. J Am Coll Cardiol 2008;51:793e801.
  • 22. Melby SJ, George JF, Picone DJ, Wallace JP, Davies JE, George DJ, et al. A time-related parametric risk factor analysis for postoperative atrial fibrillation after heart surgery. J Thorac Cardiovasc Surg 2015;149:886e92.
  • 23. Savran M, Engin M, Guvenc O, Yuksek HF, Sunbul SA, Turk T, et al. Predictive Value of HATCH Scoring and Waist-to-Height Ratio in Atrial Fibrillation Following Coronary Artery Bypass Operations Performed with Cardiopulmonary Bypass. J Saudi Heart Assoc. 2021;33(2):116-23.
  • 24. Lardizabal JA, Deedwania PC. Atrial fibrillation in heart failure. Med Clin North Am. 2012;96:987–1000.

The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations

Year 2021, Volume: 5 Issue: 8, 780 - 784, 01.08.2021
https://doi.org/10.28982/josam.957145

Abstract

Background/Aim: The rate of postoperative atrial fibrillation (PoAF) after coronary artery bypass graft (CABG) operations ranges between 25-40%. Inflammation plays an important role in the pathogenesis of PoAF, and mean platelet volume and lymphocyte count are important inflammatory parameters. This study aimed to investigate the importance of the mean platelet to lymphocyte ratio (MPVLR) in predicting PoAF after CABG operations.
Methods: Three hundred and eighty consecutive patients who underwent on-pump CABG in our clinic between August 2016 and August 2020 were included in this retrospective observational cohort study. Patients with a known history of atrial fibrillation, reoperations, emergency operations, patients who had acute coronary syndrome within the last month, combined surgeries, those with systemic inflammatory disease, chronic autoimmune disease, chronic liver/kidney disease, and hematological diseases, and patients under steroid therapy were excluded from the study. Patients who did not develop postoperative PoAF were included in Group 1, while those who did were included in Group 2.
Results: There were 319 patients in Group 1 with a median age of 59 (32-83) years, and 61 patients in Group 2, with a median age of 66 (38-86) years (P<0.001). There was no difference between the groups in terms of gender distribution, hypertension (HT), diabetes mellitus (DM), smoking, body mass index, hyperlipidemia, ejection fraction, and current medical treatments (such as Angiotensin-converting enzyme inhibitor and beta-blocker therapy). The rate of chronic obstructive pulmonary disease (P=0.017), as well as MPV, MPVLR, intensive care unit stay and total hospitalization times were significantly higher (P<0.001 for all) in Group 2, while lymphocyte levels were significantly lower (P=0.006). Based on multivariate analysis, being over 70 years old (OR: 2.432, CI 95%: 1.966-3.723, P<0.001), having an ejection fraction below 35% (OR: 1.325, CI 95%: 1.190-1.1894, P=0.021) and MPVLR (OR: 1.821, 95%CI: 1.645-2.1592, P<0.001) were independent predictors of PoAF.
Conclusion: We found that the preoperative MPVLR value, which can be obtained from a simple hemogram test, is an important predictor of PoAF in patients who underwent CABG. MPVLR value can be a marker in determining risky groups preoperatively.

References

  • 1. As AK, Engin M, Türk T. Early-term results of early coronary artery bypass graft surgery in patients undergoing primary percutaneous coronary intervention due to acute coronary syndrome. Eur Res J. 2020;7(1):59-65.
  • 2. Abanoz M, Engin M. The effect of the relationship between post-cardiotomy neutrophil/lymphocyte ratio and platelet counts on early major adverse events after isolated coronary artery bypass grafting. Turk Gogus Kalp Damar Cerrahisi Derg. 2021 Jan 13;29(1):36-44.
  • 3. Engin M, Ozsin KK, Savran M, Guvenc O, Ozyazicioglu AF. Visceral Adiposity Index and Prognostic Nutritional Index in Predicting Atrial Fibrillation after On-Pump Coronary Artery Bypass Operations: a Prospective Study. Braz J Cardiovasc Surg. 2020 Dec 23. doi: 10.21470/1678-9741-2020-0044.
  • 4. Ozturk S, Kalyoncuoglu M, Sahin M. Comparison of SYNTAX Score I and SYNTAX Score II for Predicting Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Graft Surgery. Heart Surg Forum 2019;22(5):E319-E324.
  • 5. Erdolu B, As AK, Engin M. The Relationship between the HATCH Score, Neutrophil to Lymphocyte Ratio and Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Graft Surgery. Heart Surg Forum. 2020 Feb 27;23(1):E088-E092.
  • 6. Şahinalp Ş, Çeviker K, Soyal MFT, Gür AK. Retrospective evaluation of ultrafiltration during cardiac surgery with cardiopulmonary bypass in adult patients with increased neutrophil to lymphocyte ratio. J Surg Med. 2020;4(12):1209-14.
  • 7. Çayır MÇ, Til A. The utility of mean platelet volume as a predictor of postoperative atrial fibrillation following coronary artery bypass grafting. J Surg Med. 2020;4(6):438-42.
  • 8. Weymann A, Ali-Hasan-Al-Saegh S, Popov AF, Sabashnikov A, Mirhosseini SJ, Liu T, et al. Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis. Kardiol Pol. 2018;76(1):107-18.
  • 9. Echahidi N, Pibarot P, O’Hara G, Mathieu P. Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery. J Am Coll Cardiol. 2008;51(8):793–801.
  • 10. Martin JF, Shaw T, Heggie J, Penington DG. Measurement of the density of human platelets and its relationship to volume. Br J Haematol. 1983 Jul;54(3):337-52.
  • 11. Akgül E, Engin M, Özyazıcıoğlu AF. Effects of mean platelet volume and platelet counts on peripheral biodegradable stent restenosis. J Surg Med. 2019;3(9):663-5. 12. Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD. Mean platelet volume: a link between thrombosis and inflammation? Curr Pharm Des. 2011;17(1):47-58.
  • 12. Venkatraghavan L, Tan TP, Mehta J, Arekapudi A, Govindarajulu A, Siu E. Neutrophil Lymphocyte Ratio as a predictor of systemic inflammation - A cross-sectional study in a pre-admission setting. F1000Res. 2015 May 22;4:123.
  • 13. Erdem K, Ayhan S, Ozturk S, Bugra O, Bozoglan O, Dursin H, Yazici M, Daglar B. Usefulness of the mean platelet volume for predicting new-onset atrial fibrillation after isolated coronary artery bypass grafting. Platelets. 2014;25(1):23-6.
  • 14. Pala AA, Urcun YS. Is the Mean Platelet Volume a Predictive Factor for Atrial Fibrillation Developing After Coronary Artery Bypass Grafting in Elderly Patients? Heart Surg Forum. 2020 Nov 2;23(6):E809-E814.
  • 15. Berkovitch A, Younis A, Grossman Y, Segev S, Kivity S, Sidi Y, Beinart R, Goldenberg I, Maor E. Relation of Neutrophil to Lymphocyte Ratio to Risk of Incident Atrial Fibrillation. Am J Cardiol. 2019 Feb 1;123(3):396-401.
  • 16. Shao Q, Chen K, Rha SW, Lim HE, Li G, Liu T. Usefulness of Neutrophil/Lymphocyte Ratio as a Predictor of Atrial Fibrillation: A Meta-analysis. Arch Med Res. 2015 Apr;46(3):199-206.
  • 17. Liu Z, Nguyen Khuong J, Borg Caruana C, Jackson SM, Campbell R, Ramson DM, et al. The Prognostic Value of Elevated Perioperative Neutrophil-Lymphocyte Ratio in Predicting Postoperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-Analysis. Heart Lung Circ. 2020 Jul;29(7):1015-24.
  • 18. Hudzik B, Szkodziński J, Lekston A, Gierlotka M, Poloński L, Gąsior M. Mean platelet volume-to-lymphocyte ratio: a novel marker of poor short- and long-term prognosis in patients with diabetes mellitus and acute myocardial infarction. J Diabetes Complications. 2016 Aug;30(6):1097-102.
  • 19. Chen SY, Lin YS, Cheng YF, Wang H, Niu XT, Zhang WL. Mean Platelet Volume-To-Lymphocyte Ratio Predicts Poor Functional Outcomes Among Ischemic Stroke Patients Treated With Intravenous Thrombolysis. Front Neurol. 2019 Dec 10;10:1274.
  • 20. Erdolu B, Engin M. The effect of mean platelet volume-to-lymphocyte ratio on symptom onset in patients with carotid artery stenosis. Turk J Vasc Surg 2021;30(1):7-12.
  • 21. Echahidi N, Pibarot P, O'Hara G, Mathieu P. Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery. J Am Coll Cardiol 2008;51:793e801.
  • 22. Melby SJ, George JF, Picone DJ, Wallace JP, Davies JE, George DJ, et al. A time-related parametric risk factor analysis for postoperative atrial fibrillation after heart surgery. J Thorac Cardiovasc Surg 2015;149:886e92.
  • 23. Savran M, Engin M, Guvenc O, Yuksek HF, Sunbul SA, Turk T, et al. Predictive Value of HATCH Scoring and Waist-to-Height Ratio in Atrial Fibrillation Following Coronary Artery Bypass Operations Performed with Cardiopulmonary Bypass. J Saudi Heart Assoc. 2021;33(2):116-23.
  • 24. Lardizabal JA, Deedwania PC. Atrial fibrillation in heart failure. Med Clin North Am. 2012;96:987–1000.
There are 24 citations in total.

Details

Primary Language English
Subjects Cardiovascular Surgery
Journal Section Research article
Authors

Arif Gucu 0000-0002-7464-3362

Publication Date August 1, 2021
Published in Issue Year 2021 Volume: 5 Issue: 8

Cite

APA Gucu, A. (2021). The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations. Journal of Surgery and Medicine, 5(8), 780-784. https://doi.org/10.28982/josam.957145
AMA Gucu A. The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations. J Surg Med. August 2021;5(8):780-784. doi:10.28982/josam.957145
Chicago Gucu, Arif. “The Importance of Mean Platelet Volume to Lymphocyte Ratio in Predicting Atrial Fibrillation After Coronary Bypass Operations”. Journal of Surgery and Medicine 5, no. 8 (August 2021): 780-84. https://doi.org/10.28982/josam.957145.
EndNote Gucu A (August 1, 2021) The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations. Journal of Surgery and Medicine 5 8 780–784.
IEEE A. Gucu, “The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations”, J Surg Med, vol. 5, no. 8, pp. 780–784, 2021, doi: 10.28982/josam.957145.
ISNAD Gucu, Arif. “The Importance of Mean Platelet Volume to Lymphocyte Ratio in Predicting Atrial Fibrillation After Coronary Bypass Operations”. Journal of Surgery and Medicine 5/8 (August 2021), 780-784. https://doi.org/10.28982/josam.957145.
JAMA Gucu A. The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations. J Surg Med. 2021;5:780–784.
MLA Gucu, Arif. “The Importance of Mean Platelet Volume to Lymphocyte Ratio in Predicting Atrial Fibrillation After Coronary Bypass Operations”. Journal of Surgery and Medicine, vol. 5, no. 8, 2021, pp. 780-4, doi:10.28982/josam.957145.
Vancouver Gucu A. The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations. J Surg Med. 2021;5(8):780-4.