Abstract
AbstractA Case of Rhino-Orbital Mucormycosis with Cryptococcus & Mucor in Diabetes Mellitus Mucormycosis is a severe fungal infection which has mortal course in immunosuppressive patients. Zygomycetes, aspergilli and other fungi existing in the environment may be the causative agents in this fungal infection with high morbidity and mortality especially in diabetic patients. Early diagnosis and management prolong survival in mucormycosis cases. The case presented in this paper is about a mixed mucormycosis case caused by zygomycetes and Criptococcus laurentii, which rarely infect human. It is the first one to be reported in literature. The case was a 52 years old female patient with diabetes mellitus type 2 for 15 years and had a splenectomy 3 years ago. She had necrosis on palate and loss of vision due to right optic perineuritis. Despite the appropriate treatment and surgical debridement, the patient was lost because of secondary nosocomial infection to pneumonia. In this case report we aim to emphasize the importance of early diagnosis and treatment as well as the devastating effect of probable serious nosocomial pneumonia on survival of diabetic patients with fungal infections and to present the mucormycosis with two different agents.
References
- Yohai RA, Bullock JD, Aziz AA Markert RT. Survival factors in rhino-orbital-cerebral mucormycosis: major review. Surv Ophthal 1994;39(l):3-22
- Song YM, Shin SY. Bilateral Ophthalmic Artery occlusion in rhino-orbito-cerebral mucorrnycosis. Korean Journal of Ophthalmology 2008;22(l):66-9.
- Yıldırm M, Yorgancılar E, Topçu İ, Meriç F. Rino-serebral mukormikozis: Palatal nekroz. KBB-Forum 2009;8(3):75-8. 4. Hayat M, Musthaq S, Saba S, Saif R. Rhino-orbital- mucormycosis as a presenting manifestation of gestational diabetes mellitus. Indian J Endocrinol Metab 2011;15(Suppl l):S65-6.
- Shankar EM, Kumarasamy N, Bela D, Renuka S, Kownhar H, Suniti S, Raj an R, Rao UA. Pneumonia and pleural effusion due to Cryptococcus laurentii in a clinically proven case ofAlDS. Can RespirJ2006;13(5):275-8.
- Ribes JA, Vanover-Sams CL, Baker D. Zygomycetes in human disease. Clinical Microbiology Reviews 2000;l3(2):236-301.
- Liang KP, Tleyj eh IM, Wilson WR, Roberts GD, Temesgeni Z. Rhino-orbitocerebral mucormycosis caused by
- Gorjon PS, Perez PB, Caletrio AB, Herrera MH, Gonzales FS, Canibano RF. Rhino-orbito-cerebral mucormycosis, a
- Downing MA, Omar AH, Sabri E, McCarthy AE. Information on the internet for asplenic patients: a
- Demiroğlu YZ, Turunç T, Erkan AN, Alkan Ö, Alışkan HE, Çolakoğlu Ş, Arslan H. Posakonazol ile tedavi edilen
- Bhansali A, Bhadada S, Sharma A, Suresh V, Gupta A, Singh P, Chakarbaıti A, Dash RJ. Presentation and outcome
- Hadzri M H, Azarisman S M, Fauzi A R M, Kahairi A. Invasive rhinocerebral mucormycosis with orbital
- Bhansali A, Sharma A, Kashyap A, Gupta A, Dash JR. Mucor endophthalmitis. Acta Ophthalmol Scand
- Arda B, Erdem A, Sipahi OR, Taşbakan MI, Pullukçu H, Taşbakan MS, Ceylan N, Metin DY, Midilli R, Yamazhan T,
- Fihman V, Le MonnierA, Corvec S, J aureguy F, Tankovic J, Jacquier H, Carbonnelle E, Bille E, Illiaquer M, Cattoir V,
- Zahar JR. Stenotrophomonas maltophilia-The most worrisome threat among unusual non-fermentative gram- negative bacilli from hospitalized patients: A prospective multicenter study. Journal of Infection 2012;64(4):39l-8
Abstract
Türkçe Özet: Mukormikozis immunsüpressif hastalarda mortal seyreden ciddi bir mantar enfeksiyonudur. Özellikle diyabetik hastalarda morbidite ve mortalitesi yüksek olan bu fungal enfeksiyonda ortamda bulunan zigomiçetler, aspergillozlar ve diğer mantarlar etken olabilir. Mukormikoz olgularında erken tanı ve tedavi yaşam süresini uzatır. Bu yazıda, insanda çok nadir enfeksiyon yapan ve ilk defa olarak Criptococcus laurentii ve zigomiçete bağlı miks bir mukormikoz olgusu tanımlandı. Olgu onbeş yıldan beri tip 2 diyabet ve üç yıl önce splenektomisi yapılmış 52 yaşında bir bayan hasta idi. Hastanın damakta nekrozu ve sağ optik perinörite bağlı görme kaybı vardı. Uygun tedavi ve cerrahi debridmana rağmen hasta gelişen sekonder nozokomiyal pnömoni sonucu kaybedildi. Bu sunumun amacı diyabetik hastalarda fungal enfeksiyonların erken tanı ve tedavisinin yanı sıra, gelişecek ciddi nozokomiyal pnömonilerinde yaşam süresini olumsuz etkileyebileceğine dikkat çekmek ve iki farklı mantar enfeksiyonu görülen bir mukor olgusunu sunmaktır.
References
- Yohai RA, Bullock JD, Aziz AA Markert RT. Survival factors in rhino-orbital-cerebral mucormycosis: major review. Surv Ophthal 1994;39(l):3-22
- Song YM, Shin SY. Bilateral Ophthalmic Artery occlusion in rhino-orbito-cerebral mucorrnycosis. Korean Journal of Ophthalmology 2008;22(l):66-9.
- Yıldırm M, Yorgancılar E, Topçu İ, Meriç F. Rino-serebral mukormikozis: Palatal nekroz. KBB-Forum 2009;8(3):75-8. 4. Hayat M, Musthaq S, Saba S, Saif R. Rhino-orbital- mucormycosis as a presenting manifestation of gestational diabetes mellitus. Indian J Endocrinol Metab 2011;15(Suppl l):S65-6.
- Shankar EM, Kumarasamy N, Bela D, Renuka S, Kownhar H, Suniti S, Raj an R, Rao UA. Pneumonia and pleural effusion due to Cryptococcus laurentii in a clinically proven case ofAlDS. Can RespirJ2006;13(5):275-8.
- Ribes JA, Vanover-Sams CL, Baker D. Zygomycetes in human disease. Clinical Microbiology Reviews 2000;l3(2):236-301.
- Liang KP, Tleyj eh IM, Wilson WR, Roberts GD, Temesgeni Z. Rhino-orbitocerebral mucormycosis caused by
- Gorjon PS, Perez PB, Caletrio AB, Herrera MH, Gonzales FS, Canibano RF. Rhino-orbito-cerebral mucormycosis, a
- Downing MA, Omar AH, Sabri E, McCarthy AE. Information on the internet for asplenic patients: a
- Demiroğlu YZ, Turunç T, Erkan AN, Alkan Ö, Alışkan HE, Çolakoğlu Ş, Arslan H. Posakonazol ile tedavi edilen
- Bhansali A, Bhadada S, Sharma A, Suresh V, Gupta A, Singh P, Chakarbaıti A, Dash RJ. Presentation and outcome
- Hadzri M H, Azarisman S M, Fauzi A R M, Kahairi A. Invasive rhinocerebral mucormycosis with orbital
- Bhansali A, Sharma A, Kashyap A, Gupta A, Dash JR. Mucor endophthalmitis. Acta Ophthalmol Scand
- Arda B, Erdem A, Sipahi OR, Taşbakan MI, Pullukçu H, Taşbakan MS, Ceylan N, Metin DY, Midilli R, Yamazhan T,
- Fihman V, Le MonnierA, Corvec S, J aureguy F, Tankovic J, Jacquier H, Carbonnelle E, Bille E, Illiaquer M, Cattoir V,
- Zahar JR. Stenotrophomonas maltophilia-The most worrisome threat among unusual non-fermentative gram- negative bacilli from hospitalized patients: A prospective multicenter study. Journal of Infection 2012;64(4):39l-8
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | March 1, 2013 |
| Submission Date | June 13, 2014 |
| Published in Issue | Year 2013 Volume: 6 Issue: 1 |
Cite
MEU Journal of Health Sciences Assoc was began to the publishing process in 2008 under the supervision of Assoc. Prof. Gönül Aslan, Editor-in-Chief, and affiliated to Mersin University Institute of Health Sciences. In March 2015, Prof. Dr. Caferi Tayyar Şaşmaz undertook the Editor-in Chief position and since then he has been in charge.
Publishing in three issues per year (April - August - December), it is a multisectoral refereed scientific journal. In addition to research articles, scientific articles such as reviews, case reports and letters to the editor are published in the journal. Our journal, which has been published via e-mail since its inception, has been published both online and in print. Following the Participation Agreement signed with TÜBİTAK-ULAKBİM Dergi Park in April 2015, it has started to accept and evaluate online publications.
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