Abstract
Abstract
Herpes simplex virus-1
(HSV-1) is a double-stranded DNA virus and is the most common cause of fatal
sporadic encephalitis world-wide. HSV-1 encephalitis is characterized by rapid
onset of fever, headache, altered mental status, seizures and focal
neurological symptoms. Paraneoplastic and autoimmune limbic encephalitis (LE)
is a condition which presents with similar signs and symptoms, and which develops
as a result of antibodies raised against the tumor or synaptic proteins. In patients
with this condition, bacterial and viral causes should be excluded, particularly
HSV-1 encephalitis. In this report, we present a rare case of limbic encephalitis associated with HSV-1
virus.
References
- Barnett EM, Jacobsen G, Evans G, et al. Herpes simplex encephalitis in the temporal cortex and limbic system after trigeminal nerve inoculation. J Infect Dis 1994; 169:782.
- Stanberry LR, Floyd-Reising SA, Connelly BL, et al. Herpes simplex viremia: report of eight pediatric cases and review of the literature. Clin Infect Dis 1994; 18:401.
- Harel L, Smetana Z, Prais D, et al. Presence of viremia in patients with primary herpetic gingivostomatitis. Clin Infect Dis 2004; 39:636.
- Robyn S Klein, MD, PhD. Herpes simplex virus type 1 encephalitis. UpToDate May 2016.
- Fisher CM. Hypomanic symptoms caused by herpes simplex encephalitis. Neurology 1996; 47:1374.
- Hanley DF, Johnson RT, Whitley RJ. Yes, brain biopsy should be a prerequisite for herpes simplex encephalitis treatment. Arch Neurol 1987; 44:1289.
- Corey L, Whitley RJ, Stone EF, et all. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet 1988; 1:1.
- Nahmias AJ, Whitley RJ, Visintine AN, et al. Herpes simplex virus encephalitis: laboratory evaluations and their diagnostic significance. J Infect Dis 1982; 145:829.
- Bradford RD, Pettit AC, Wright PW, et al. Herpes simplex encephalitis during treatment with tumor necrosis factor-alpha inhibitors. Clin Infect Dis 2009; 49:924.
- Razavi B, Razavi M. Herpes simplex encephalitis--an atypical case. Infection 2001; 29:357.
- Tyler KL. Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's. Herpes 2004; 11 Suppl 2:57A.
- Boivin G. Diagnosis of herpesvirus infections of the central nervous system. Herpes 2004; 11 Suppl 2:48A.
- Levitz RE. Herpes simplex encephalitis: a review. Heart Lung 1998; 27:209.
- Patrick Navin, Norman Delanty,Paul Brennan, et all. Herpes simplex virus encephalitis involving the right thalamus. BMJ Case Rep. 2013 Jun 19; 010206.
- Suresh Thirunavukarasu. Temporal and Pontine Involvement in a Case of Herpes Simplex Encephalitis, Presenting as Kluver Bucy Syndrome. J Clin Imaging Sci. 2011; 1: 43.
- Yoichi Ono, Yasuhiro Manabe, Hirotake Nishimura, et all. Unusual progression of herpes simplex encephalitis with basal ganglia and extensive white matter involvement. Neurol Int. 2009 Nov 16;1(1).
- Wasay M, Mekan SF, Khelaeni B, et al. Extra temporal involvement in herpes simplex encephalitis. Eur J Neurol 2005; 12:475.
- Lai CW, Gragasin ME. Electroencephalography in herpes simplex encephalitis. J Clin Neurophysiol. 1988 Jan; 5(1):87-103.
Abstract
Özet
Dünyadaki
ölümcül sporadik ensefalitlerin en sık etkeni olan Herpes simplex virüs-1
(HSV-1); çift sarmallı DNA virüsüdür. HSV-1 ensefaliti klinik olarak hızlı
başlangıçlı ateş, baş ağrısı, bilinç değişiklikleri, nöbetler ve fokal
nörolojik belirtiler ile karakterizedir. Benzer semptom ve bulgularla seyreden
paraneoplastik ve otoimmün limbik ensefalit (LE) ise, tümör veya sinaptik
proteinlere karşı oluşan antikorlarla gelişmekte ve bu hastalarda bakteriyel ve
viral nedenlerin, özellikle HSV-1’e bağlı gelişen ensefalitin ekarte edilmesi
gerekmektedir. Bu makalede HSV-1 virüsü
ile ilişkili limbik ensefalit gelişen bir olgu sunuldu.
References
- Barnett EM, Jacobsen G, Evans G, et al. Herpes simplex encephalitis in the temporal cortex and limbic system after trigeminal nerve inoculation. J Infect Dis 1994; 169:782.
- Stanberry LR, Floyd-Reising SA, Connelly BL, et al. Herpes simplex viremia: report of eight pediatric cases and review of the literature. Clin Infect Dis 1994; 18:401.
- Harel L, Smetana Z, Prais D, et al. Presence of viremia in patients with primary herpetic gingivostomatitis. Clin Infect Dis 2004; 39:636.
- Robyn S Klein, MD, PhD. Herpes simplex virus type 1 encephalitis. UpToDate May 2016.
- Fisher CM. Hypomanic symptoms caused by herpes simplex encephalitis. Neurology 1996; 47:1374.
- Hanley DF, Johnson RT, Whitley RJ. Yes, brain biopsy should be a prerequisite for herpes simplex encephalitis treatment. Arch Neurol 1987; 44:1289.
- Corey L, Whitley RJ, Stone EF, et all. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet 1988; 1:1.
- Nahmias AJ, Whitley RJ, Visintine AN, et al. Herpes simplex virus encephalitis: laboratory evaluations and their diagnostic significance. J Infect Dis 1982; 145:829.
- Bradford RD, Pettit AC, Wright PW, et al. Herpes simplex encephalitis during treatment with tumor necrosis factor-alpha inhibitors. Clin Infect Dis 2009; 49:924.
- Razavi B, Razavi M. Herpes simplex encephalitis--an atypical case. Infection 2001; 29:357.
- Tyler KL. Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's. Herpes 2004; 11 Suppl 2:57A.
- Boivin G. Diagnosis of herpesvirus infections of the central nervous system. Herpes 2004; 11 Suppl 2:48A.
- Levitz RE. Herpes simplex encephalitis: a review. Heart Lung 1998; 27:209.
- Patrick Navin, Norman Delanty,Paul Brennan, et all. Herpes simplex virus encephalitis involving the right thalamus. BMJ Case Rep. 2013 Jun 19; 010206.
- Suresh Thirunavukarasu. Temporal and Pontine Involvement in a Case of Herpes Simplex Encephalitis, Presenting as Kluver Bucy Syndrome. J Clin Imaging Sci. 2011; 1: 43.
- Yoichi Ono, Yasuhiro Manabe, Hirotake Nishimura, et all. Unusual progression of herpes simplex encephalitis with basal ganglia and extensive white matter involvement. Neurol Int. 2009 Nov 16;1(1).
- Wasay M, Mekan SF, Khelaeni B, et al. Extra temporal involvement in herpes simplex encephalitis. Eur J Neurol 2005; 12:475.
- Lai CW, Gragasin ME. Electroencephalography in herpes simplex encephalitis. J Clin Neurophysiol. 1988 Jan; 5(1):87-103.
Details
| Subjects | Health Care Administration |
|---|---|
| Journal Section | Case report |
| Authors | |
| Publication Date | April 5, 2018 |
| Published in Issue | Year 2018 Volume: 10 Issue: 1 |
e-ISSN: 2548-0251
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