A Pediatric Case of Concomitant Leishmania and Brucella Infection

Perihan Yasemen Canöz; Gökhan Tümgör; İbrahim Hakan Bucak; Göksel Leblebisatan; Fatma Levent İstifli; Mehmet Turgut

doi:10.4274/jcp.07379

Pediatrik Bir Olguda Leishmania ve Brucella Birlikte Enfeksiyonu

Year 2014, Volume: 12 Issue: 2, 103 - 106, 01.09.2014

Perihan Yasemen Canöz Gökhan Tümgör İbrahim Hakan Bucak Göksel Leblebisatan Fatma Levent İstifli Mehmet Turgut

https://doi.org/10.4274/jcp.07379

Abstract

Viseral leishmaniasis; Leishmania türüne ait protozoal parazitlerin neden olduğu bir hastalıktır. Brusellozis; insanlara enfekte hayvanlardan bulaşan zoonotik bir hastalıktır. On altı yaşında kız hasta kliniğimize güçsüzlük, miyalji, solukluk, karın ağrısı, ayaklarda şişlik, tüm vücutta döküntü şikayetleri ile başvurdu. Yapılan klinik muayenede ateş yüksekliği, splenomegali, üst ve alt ekstremitelerde ödem ve tüm vücutta eritem tespit edildi. Hastaya ait Brusella aglütinasyon testi 1/640 titre ile pozitif idi. Hastaya başlanan Brusella tedavisinin başarısız olması üzerine yapılan kemik iliği incelemesinde hücre içi ve hücre dışı amastigotlar tespit edildi. Kalaazar dipstick testi rk-39 pozitif idi. Kala-azar ve Brusellozis tanısı ile başarılı şekilde tedavi edilen 16 yaşında kız hasta tarafımızdan sunuldu

Keywords

Leishmaniasis, brusellozis, kemik iliği aspirasyonu

References

1. Kar K. Serodiagnosis of leishmaniasis. Crit Rev Microbiol 1995;21:123-52.
2. Garcia LS, Bruekner DA. Diagnostic Medical Parasitology. Fourth Edition, Washington DC: ASM Pres, 2001:205-34.
3. Unat EK, Yucel A, Atlas K, Samastı M, Unat’ın Tıp Parazitolojisi. 5. baskı. İstanbul: Cerrahpasa Tıp Fak. Yayını 1995:564-86.
4. Murray HW, Berman JD, Davies CR, Saravia NG. Advances in leishmaniasis. Lancet 2005;366:1561-77.
5. Murray HW. Clinical and Experimental Advances in Treatment of Visseral Leishmaniasis.Antimicrob Agents Chemother 2001;45:2185-97.
6. Minodier P, Garnier JM. Childhood visceral leishmaniasis in Provence. Arch Pediatr 2000;7:572-77.
7. WHO Division of Control of Tropical Diseases: Leismaniasis Control, 1998.
8. Ozensoy S, Ozbel Y, Turgay N, Alkan MZ, Gul K, GilmanSachs A, et al. Serodiagnosis and epidemiology of visceral leishmaniasis in Turkey. Am J Trop Med Hyg 1998;59:363-9.
9. Aydoğdu İ, Dinçer SL. Non-epidemiological kala-azar cases in Turkey. (letter) Acta Paediatr 1995;84:1034.
10. Kocabaş E, Antmen B, Alhan E, Yıldıztaş D, Aksaray N. Çocukluk çağında kala-azar. Çukurova Üniversitesi Tıp Fakültesi Dergisi 1998;23:95-101.
11. Wyler DJ, Leismaniasis in Behrman, RE, Kliegman RM, Arvin, A.M. (Eds): Nelson Text Book of Pediatrics, WB Saunders Co, 1992;14:892-94.
12. American Academy of Pediatrics, 1997 Red Book: Report of the Committee on Infectious Diseases, Twenty-Fourth Edition, 1997:321-23.
13. Lim ML, Rickman LS. Brucellosis, Infect Dis Clin Pract 2004;12:7-14.
14. Sözen TH: Bruselloz, “Topçu AW, Söyletir G, Doğanay M (eds): İnfeksiyon Hastalıkları, 2. baskı” kitabında s. 636-42, Nobel Tıp Kitabevleri, İstanbul (2002).
15. Tansel Ö, Yavuz M, Kuloğlu F Akata F. Trakya Üniversitesi Hastanesi’ne başvuran 40 bruselloz olgusunun değerlendirilmesi, İnfeksiyon Derg 2003;17:1-4.
16. Sundar S, Rai M. Clinical and diagnotic laboratory immunology, Sept 2002:951-58.
17. Fakhar M, Banimostafavi E, Motazedian MH, Asgari Q. Coinfection of Leishmania infantum and Brucella spp in Iran. Comp Clin Pathol 2009;18:93-4.

A Pediatric Case of Concomitant Leishmania and Brucella Infection

Year 2014, Volume: 12 Issue: 2, 103 - 106, 01.09.2014

Perihan Yasemen Canöz Gökhan Tümgör İbrahim Hakan Bucak Göksel Leblebisatan Fatma Levent İstifli Mehmet Turgut

https://doi.org/10.4274/jcp.07379

Abstract

Visceral leishmaniasis Kala-azar is a disease caused by protozoan parasites of the Leishmania Genus, and Brucellosis is a zoonotic disease infecting human host by infective animals. A sixteen year-old girl presented to our clinic with complaints of fatigue, myalgia, pallor, stomach ache, leg swelling, and diffuse body rash. Physical examination revealed findings of elevated body temperature, splenomegaly, upper and lower extremity edema, and diffuse erythema. Patients’ brucella agglutination test was positive at titers 1: 640. Since the treatment of Brucellosis was unsuccessful, other disease processes were investigated and extracellular and intracellular amastigots were detected in the bone marrow aspirate preparations. Kala-azar dipstick rk-39 was also positive. We present a 16 year-old girl who was diagnosed with Kala-azar and Brucellosis together infection and successfully treated

Keywords

Leishmaniasis, brucellosis, bone marrow aspiration

References

1. Kar K. Serodiagnosis of leishmaniasis. Crit Rev Microbiol 1995;21:123-52.
2. Garcia LS, Bruekner DA. Diagnostic Medical Parasitology. Fourth Edition, Washington DC: ASM Pres, 2001:205-34.
3. Unat EK, Yucel A, Atlas K, Samastı M, Unat’ın Tıp Parazitolojisi. 5. baskı. İstanbul: Cerrahpasa Tıp Fak. Yayını 1995:564-86.
4. Murray HW, Berman JD, Davies CR, Saravia NG. Advances in leishmaniasis. Lancet 2005;366:1561-77.
5. Murray HW. Clinical and Experimental Advances in Treatment of Visseral Leishmaniasis.Antimicrob Agents Chemother 2001;45:2185-97.
6. Minodier P, Garnier JM. Childhood visceral leishmaniasis in Provence. Arch Pediatr 2000;7:572-77.
7. WHO Division of Control of Tropical Diseases: Leismaniasis Control, 1998.
8. Ozensoy S, Ozbel Y, Turgay N, Alkan MZ, Gul K, GilmanSachs A, et al. Serodiagnosis and epidemiology of visceral leishmaniasis in Turkey. Am J Trop Med Hyg 1998;59:363-9.
9. Aydoğdu İ, Dinçer SL. Non-epidemiological kala-azar cases in Turkey. (letter) Acta Paediatr 1995;84:1034.
10. Kocabaş E, Antmen B, Alhan E, Yıldıztaş D, Aksaray N. Çocukluk çağında kala-azar. Çukurova Üniversitesi Tıp Fakültesi Dergisi 1998;23:95-101.
11. Wyler DJ, Leismaniasis in Behrman, RE, Kliegman RM, Arvin, A.M. (Eds): Nelson Text Book of Pediatrics, WB Saunders Co, 1992;14:892-94.
12. American Academy of Pediatrics, 1997 Red Book: Report of the Committee on Infectious Diseases, Twenty-Fourth Edition, 1997:321-23.
13. Lim ML, Rickman LS. Brucellosis, Infect Dis Clin Pract 2004;12:7-14.
14. Sözen TH: Bruselloz, “Topçu AW, Söyletir G, Doğanay M (eds): İnfeksiyon Hastalıkları, 2. baskı” kitabında s. 636-42, Nobel Tıp Kitabevleri, İstanbul (2002).
15. Tansel Ö, Yavuz M, Kuloğlu F Akata F. Trakya Üniversitesi Hastanesi’ne başvuran 40 bruselloz olgusunun değerlendirilmesi, İnfeksiyon Derg 2003;17:1-4.
16. Sundar S, Rai M. Clinical and diagnotic laboratory immunology, Sept 2002:951-58.
17. Fakhar M, Banimostafavi E, Motazedian MH, Asgari Q. Coinfection of Leishmania infantum and Brucella spp in Iran. Comp Clin Pathol 2009;18:93-4.

There are 17 citations in total.

Details

Primary Language	English
Journal Section	Case Report
Authors	Perihan Yasemen Canöz This is me Gökhan Tümgör This is me İbrahim Hakan Bucak Göksel Leblebisatan This is me Fatma Levent İstifli This is me Mehmet Turgut This is me
Publication Date	September 1, 2014
Published in Issue	Year 2014 Volume: 12 Issue: 2

Cite

APA	Canöz, P. Y., Tümgör, G., Bucak, İ. H., Leblebisatan, G., et al. (2014). A Pediatric Case of Concomitant Leishmania and Brucella Infection. Güncel Pediatri, 12(2), 103-106. https://doi.org/10.4274/jcp.07379
AMA	Canöz PY, Tümgör G, Bucak İH, Leblebisatan G, İstifli FL, Turgut M. A Pediatric Case of Concomitant Leishmania and Brucella Infection. Güncel Pediatri. September 2014;12(2):103-106. doi:10.4274/jcp.07379
Chicago	Canöz, Perihan Yasemen, Gökhan Tümgör, İbrahim Hakan Bucak, Göksel Leblebisatan, Fatma Levent İstifli, and Mehmet Turgut. “A Pediatric Case of Concomitant Leishmania and Brucella Infection”. Güncel Pediatri 12, no. 2 (September 2014): 103-6. https://doi.org/10.4274/jcp.07379.
EndNote	Canöz PY, Tümgör G, Bucak İH, Leblebisatan G, İstifli FL, Turgut M (September 1, 2014) A Pediatric Case of Concomitant Leishmania and Brucella Infection. Güncel Pediatri 12 2 103–106.
IEEE	P. Y. Canöz, G. Tümgör, İ. H. Bucak, G. Leblebisatan, F. L. İstifli, and M. Turgut, “A Pediatric Case of Concomitant Leishmania and Brucella Infection”, Güncel Pediatri, vol. 12, no. 2, pp. 103–106, 2014, doi: 10.4274/jcp.07379.
ISNAD	Canöz, Perihan Yasemen et al. “A Pediatric Case of Concomitant Leishmania and Brucella Infection”. Güncel Pediatri 12/2 (September 2014), 103-106. https://doi.org/10.4274/jcp.07379.
JAMA	Canöz PY, Tümgör G, Bucak İH, Leblebisatan G, İstifli FL, Turgut M. A Pediatric Case of Concomitant Leishmania and Brucella Infection. Güncel Pediatri. 2014;12:103–106.
MLA	Canöz, Perihan Yasemen et al. “A Pediatric Case of Concomitant Leishmania and Brucella Infection”. Güncel Pediatri, vol. 12, no. 2, 2014, pp. 103-6, doi:10.4274/jcp.07379.
Vancouver	Canöz PY, Tümgör G, Bucak İH, Leblebisatan G, İstifli FL, Turgut M. A Pediatric Case of Concomitant Leishmania and Brucella Infection. Güncel Pediatri. 2014;12(2):103-6.