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BORDERLINE OVER TÜMÖRLERİNDE FROZEN SECTİON İLE TANI DOĞRULUĞU

Year 2023, Volume: 23 Issue: 2, 9 - 14, 06.11.2023

Abstract

Amaç: Bu çalışmada adneksiyal kitle nedeniyle opere edilen ve frozen section ile borderline over tümörü (BOT) tanısı konulan olguların son patolojileri ile arasındaki ilişki araştırıldı.
Gereç ve Yöntem: Bu araştırma, 2010-2022 yılları arasında Necmettin Erbakan Üniversitesi Meram Tip Fakültesi Hastanesi'nde adneksiyal kitle cerrahisi geçiren ve frozen section tanısı BOT olarak kaydedilen 68 hasta incelendi. Frozen section yaklaşımının tanısal doğruluğu, tek değişkenli ve çok değişkenli analizler kullanarak belirlendi.
Bulgular ve Sonuç: Frozen sectiondan farklı olarak kesin patoloji ile malign tanısı konulan hastaların özellikleri araştırıldı. Bu durumlarda ameliyat öncesi CFA eşik değerinin 1,16 ng/ml olduğu ve bu olguların 43 yaşından büyük olduğu belirlendi.

References

  • 1. Seidman JD, Cho KR, Ronnett BM, Kurman RJ. Surface epithelial tumors of the ovary. Blaustein's pathology of the female genital tract2002.
  • 2. Seidman JD, Kurman RJ Pathology of ovarian carcinoma. Hematology/oncology clinics of North. America. 2003;17(4):909-25, vil.
  • 3. Karseladze AI. [WHO histological classification. of ovarian tumors. Geneva, 1999 (RE Scully LH.Sobin]. Arkhiv patologii. 2005,Suppl 1-64
  • 4. Skirnisdóttir I, Garmo H, Wilander E. Holmberg L. Borderline ovarian tumors in Sweden 1960-2005: trends in incidence and age at diagnosis compared. to ovarian cancer. International journal of cancer. 2008;123(8):1897-901.
  • 5. Trimble CL, Trimble EL. Ovarian tumors of low malignant potential. ey (Williston Park, NY). 2003;17(11):1563-7; discussion 7-70, 75.
  • 6. Harter P Gershenson D, Lhomme C, Lecuru E Ledermann J. Provencher DM, et al. Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian tumors of low malignant potential (borderline ovarian tumors). International journal. of gynecological cancer: official journal of the International Gynecological Cancer Society 2014;24(9 Suppl 3):55-8
  • 7. Hart WR. Borderline epithelial tumors of the ovary. Modern pathology: an official journal of the United States and Canadian Academy of Pathology, Inc. 2005;18 Suppl 2:533-50.
  • 8. Jones MB Borderline ovarian tumors: current concepts for prognostic factors and clinical management. Clinical obstetrics and gynecology 2006,49(3):517-25.
  • 9. Lazarou A, Fotopoulou C, Coumbos A, Schouli J. Vasiljeva J. Braicu 1, et al. Long-term follow-up of borderline ovarian tumors clinical outcome and prognostic factors. Anticancer research.. 2014;34(11):6725-30.
  • 10. Mink PJ, Sherman ME, Devesa SS. Incidence. patterns of invasive and borderline ovarian tumors among white women and black women in the United States. The results from the SEER Program, 1978-1998. Cancer. 2002;95(11):2380-9
  • 11.Hannibal CG, Huusom LD, Kjaerbye-Thygesen A, Tabor A, Kjaer SK. Trends in incidence of borderline ovarian tumors in Denmark 1978-2006. Acta obstetricia et gynecologica Scandinavica 2011;90(4):305-12. 12. Goff BA, Mandel LS, Melancon CH, Muntz HG. Frequency of symptoms of ovarian cancer in women presenting to primary care clinics. Jama. 2004;291(22):2705-12.
  • 13.Geomini P, Bremer G, Kruitwagen R. Mol BW Diagnostic accuracy of frozen section diagnosis of the adnexal mass: a metaanalysis. Gynecol Oncol. 2005;96(1):1-9
  • 14.Chen YY, Lin H. Wu CH, Lan J, Tsai CC, Fu HC, et al. Factors associated with the inconsistent diagnosis between frozen section and permanent pathologic examination in borderline ovarian tumors. Journal of Obstetrics and Gynecology Research. 2021;47(8) 2729-36.
  • 15. Basaran D, Salman MC, Calis P, Ozek A, Ozgul N. Usubütün A, et al. Diagnostic accuracy of intraoperative consultation (frozen section) in borderline ovarian tumors and factors associated with misdiagnosis Journal of obstetrics and gynecology: the journal of the Institute of Obstetrics. and Gynecology: 2014;34(5):429-34.
  • 16. De Decker K, Jaroch KH, Bart J. Kooreman LE Kruitwagen RF, Nijman HW, et al. Borderline ovarian tumor frozen section diagnoses with features suspicious of invasive cancer: a retrospective study. Journal of ovarian research. 2021:14(1):1-6.
  • 17.Park JY, Lee SH, Kim KR, Kim YT, Nam JH. Accuracy of frozen section diagnosis and factors associated with final pathological diagnosis upgrade of mucinous ovarian tumors. J Gynecol Oncol. 2019:30(6):e95.
  • 18. Buza N. Frozen Section Diagnosis of Ovariant Epithelial Tumors: Diagnostic Pearls and Pitfalls. Archives of pathology & laboratory medicine. 2019;143(1):47-64
  • 19.Brun JL, Cortez A, Rouzier R, Callard P Bazot M. Uzan S. et al. Factors influencing the use and accuracy of frozen section diagnosis of epithelial ovarian tumors. American journal of obstetrics and gynecology 2008;199(3):244 el-7

Diagnosis Accuracy with Frozen Section at Borderline Ovarian Tumors

Year 2023, Volume: 23 Issue: 2, 9 - 14, 06.11.2023

Abstract

Objective: This crudy examined patients diagnosed with borderline ovarian tumors by frozen section. Some of these patients' final pathologies differed from the diagnosis of borderline ovarian tumors with frozen sections. The situations that cause this difference are the subject of this study.
Material and Methods: This research investigated 68 patients who had adnexal mass surgery at the Necmettin Erbakan University Meram Faculty of Medicine Hospital between 2010 and 2022 and whose frozen section diagnosis results were recorded as borderline ovarian tumors. The diagnostic accuracy of the frozen section approach was determined using univariate and multivariate analyses
Results: Unlike the frozen diagnosis, the features of the patients diagnosed with malignancy through definitive pathology were investigated. In these Instances, the preoperative cutoff value for carcinoembryonic antigen was 1.16 ng/ml and 43 years of age.
Results and conclusion: Unlike the frozen diagnosis, the features of the patients diagnosed with malignancy through definitive pathology were investigated. In these instances, the preoperative cutoff value for carcinoembryonic antigen was 1.16 ng/ml and 43 years of age

References

  • 1. Seidman JD, Cho KR, Ronnett BM, Kurman RJ. Surface epithelial tumors of the ovary. Blaustein's pathology of the female genital tract2002.
  • 2. Seidman JD, Kurman RJ Pathology of ovarian carcinoma. Hematology/oncology clinics of North. America. 2003;17(4):909-25, vil.
  • 3. Karseladze AI. [WHO histological classification. of ovarian tumors. Geneva, 1999 (RE Scully LH.Sobin]. Arkhiv patologii. 2005,Suppl 1-64
  • 4. Skirnisdóttir I, Garmo H, Wilander E. Holmberg L. Borderline ovarian tumors in Sweden 1960-2005: trends in incidence and age at diagnosis compared. to ovarian cancer. International journal of cancer. 2008;123(8):1897-901.
  • 5. Trimble CL, Trimble EL. Ovarian tumors of low malignant potential. ey (Williston Park, NY). 2003;17(11):1563-7; discussion 7-70, 75.
  • 6. Harter P Gershenson D, Lhomme C, Lecuru E Ledermann J. Provencher DM, et al. Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian tumors of low malignant potential (borderline ovarian tumors). International journal. of gynecological cancer: official journal of the International Gynecological Cancer Society 2014;24(9 Suppl 3):55-8
  • 7. Hart WR. Borderline epithelial tumors of the ovary. Modern pathology: an official journal of the United States and Canadian Academy of Pathology, Inc. 2005;18 Suppl 2:533-50.
  • 8. Jones MB Borderline ovarian tumors: current concepts for prognostic factors and clinical management. Clinical obstetrics and gynecology 2006,49(3):517-25.
  • 9. Lazarou A, Fotopoulou C, Coumbos A, Schouli J. Vasiljeva J. Braicu 1, et al. Long-term follow-up of borderline ovarian tumors clinical outcome and prognostic factors. Anticancer research.. 2014;34(11):6725-30.
  • 10. Mink PJ, Sherman ME, Devesa SS. Incidence. patterns of invasive and borderline ovarian tumors among white women and black women in the United States. The results from the SEER Program, 1978-1998. Cancer. 2002;95(11):2380-9
  • 11.Hannibal CG, Huusom LD, Kjaerbye-Thygesen A, Tabor A, Kjaer SK. Trends in incidence of borderline ovarian tumors in Denmark 1978-2006. Acta obstetricia et gynecologica Scandinavica 2011;90(4):305-12. 12. Goff BA, Mandel LS, Melancon CH, Muntz HG. Frequency of symptoms of ovarian cancer in women presenting to primary care clinics. Jama. 2004;291(22):2705-12.
  • 13.Geomini P, Bremer G, Kruitwagen R. Mol BW Diagnostic accuracy of frozen section diagnosis of the adnexal mass: a metaanalysis. Gynecol Oncol. 2005;96(1):1-9
  • 14.Chen YY, Lin H. Wu CH, Lan J, Tsai CC, Fu HC, et al. Factors associated with the inconsistent diagnosis between frozen section and permanent pathologic examination in borderline ovarian tumors. Journal of Obstetrics and Gynecology Research. 2021;47(8) 2729-36.
  • 15. Basaran D, Salman MC, Calis P, Ozek A, Ozgul N. Usubütün A, et al. Diagnostic accuracy of intraoperative consultation (frozen section) in borderline ovarian tumors and factors associated with misdiagnosis Journal of obstetrics and gynecology: the journal of the Institute of Obstetrics. and Gynecology: 2014;34(5):429-34.
  • 16. De Decker K, Jaroch KH, Bart J. Kooreman LE Kruitwagen RF, Nijman HW, et al. Borderline ovarian tumor frozen section diagnoses with features suspicious of invasive cancer: a retrospective study. Journal of ovarian research. 2021:14(1):1-6.
  • 17.Park JY, Lee SH, Kim KR, Kim YT, Nam JH. Accuracy of frozen section diagnosis and factors associated with final pathological diagnosis upgrade of mucinous ovarian tumors. J Gynecol Oncol. 2019:30(6):e95.
  • 18. Buza N. Frozen Section Diagnosis of Ovariant Epithelial Tumors: Diagnostic Pearls and Pitfalls. Archives of pathology & laboratory medicine. 2019;143(1):47-64
  • 19.Brun JL, Cortez A, Rouzier R, Callard P Bazot M. Uzan S. et al. Factors influencing the use and accuracy of frozen section diagnosis of epithelial ovarian tumors. American journal of obstetrics and gynecology 2008;199(3):244 el-7
There are 18 citations in total.

Details

Primary Language English
Subjects Gynecologic Oncology Surgery
Journal Section Research Article
Authors

Sıtkı Özbilgeç

Fatih Akkuş

Emine Türen Demir

Okancan Yılmaz

Pembe Oltulu

Ali Acar

Early Pub Date November 6, 2023
Publication Date November 6, 2023
Submission Date July 5, 2023
Published in Issue Year 2023 Volume: 23 Issue: 2

Cite

APA Özbilgeç, S., Akkuş, F., Demir, E. T., Yılmaz, O., et al. (2023). Diagnosis Accuracy with Frozen Section at Borderline Ovarian Tumors. Türk Jinekolojik Onkoloji Dergisi, 23(2), 9-14.
AMA Özbilgeç S, Akkuş F, Demir ET, Yılmaz O, Oltulu P, Acar A. Diagnosis Accuracy with Frozen Section at Borderline Ovarian Tumors. TRSGO Dergisi. November 2023;23(2):9-14.
Chicago Özbilgeç, Sıtkı, Fatih Akkuş, Emine Türen Demir, Okancan Yılmaz, Pembe Oltulu, and Ali Acar. “Diagnosis Accuracy With Frozen Section at Borderline Ovarian Tumors”. Türk Jinekolojik Onkoloji Dergisi 23, no. 2 (November 2023): 9-14.
EndNote Özbilgeç S, Akkuş F, Demir ET, Yılmaz O, Oltulu P, Acar A (November 1, 2023) Diagnosis Accuracy with Frozen Section at Borderline Ovarian Tumors. Türk Jinekolojik Onkoloji Dergisi 23 2 9–14.
IEEE S. Özbilgeç, F. Akkuş, E. T. Demir, O. Yılmaz, P. Oltulu, and A. Acar, “Diagnosis Accuracy with Frozen Section at Borderline Ovarian Tumors”, TRSGO Dergisi, vol. 23, no. 2, pp. 9–14, 2023.
ISNAD Özbilgeç, Sıtkı et al. “Diagnosis Accuracy With Frozen Section at Borderline Ovarian Tumors”. Türk Jinekolojik Onkoloji Dergisi 23/2 (November 2023), 9-14.
JAMA Özbilgeç S, Akkuş F, Demir ET, Yılmaz O, Oltulu P, Acar A. Diagnosis Accuracy with Frozen Section at Borderline Ovarian Tumors. TRSGO Dergisi. 2023;23:9–14.
MLA Özbilgeç, Sıtkı et al. “Diagnosis Accuracy With Frozen Section at Borderline Ovarian Tumors”. Türk Jinekolojik Onkoloji Dergisi, vol. 23, no. 2, 2023, pp. 9-14.
Vancouver Özbilgeç S, Akkuş F, Demir ET, Yılmaz O, Oltulu P, Acar A. Diagnosis Accuracy with Frozen Section at Borderline Ovarian Tumors. TRSGO Dergisi. 2023;23(2):9-14.