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Ege Journal of Medicine
2017, Cilt 56, Sayı 2, Sayfa(lar) 062-065
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A retrospective gender-comparative evaluation of the prognostic factors in differentiated thyroid cancers
Mustafa Demirpençe1, Hamiyet Yılmaz1, Pelin Tütüncüoğlu2, Ahmet Görgel3, Mithat Bahçeci4
1Tepecik Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Hastalıkları Kliniği, İzmir, Türkiye
2Atatürk Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Hastalıkları Kliniği, İzmir, Türkiye
3Medikal Park Hastanesi, Endokrinoloji ve Metabolizma Hastalıkları Kliniği, Elazığ, Türkiye
4Özel Kent Hastanesi, Endokrinoloji ve Metabolizma Hastalıkları Kliniği, İzmir, Türkiye
Keywords: Differentiated thyroid cancer, prognostic factors, gender

Aim: Differentiated thyroid cancers are the most common endocrine cancer types among all. Differentiated thyroid cancers are more common with women, but the prognosis tends to be poorer in men. This study aims to compare prognostic factors between genders in the patients who are being treated with a differentiated thyroid cancer diagnosis in İzmir Atatürk Research and Training Hospital Endocrinology Department.

Materials and Methods: The 458 patients who were treated with a diagnosis of differentiated thyroid carcinoma in our department were included in this retrospective study.

Results: Sixty-eight (14.8%) of the patients were male and 390 (85.2%) of the patients were female. The mean age of the patients included in the study was 49.8 (±12.6) at the time of diagnosis. The mean age of the male and female patients were 54.6 (±13.6) and 48.9 (±12.2), respectively (p<0.05). The medium value of the tumor size of the patients was 11.5 mm, whereas 13.5 mm in men and 11.0 mm in women (p<0.05). Lymph node metastasis was detected in 40 (18.6%) patients. In patients with lymph node metastasis, 11 (16.1%) were male. The rate of lymph node metastasis were higher in men (p<0.05). In this study, the mean age and the tumor size at the time of diagnosis and the percentage of the lymph node metastasis in men was found significantly higher than that of women.

Conclusion: Differentiated thyroid cancers tend to have poor prognosis in men and this may be due to being diagnosed on an advanced age and with a larger size.


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