Öz
Amacımız, porselen kese zemininde skuamöz hücreli safra kesesi kanseri olgumuzun radyolojik bulgularını
ve literatür eşliğinde safra kesesi kanserlerine yaklaşımı gözden geçirmektir. Safra kesesi kanserleri
gastrointestinal tümörlerin 5. sıklıkta görülen, safra yollarının ise en sık görülen maligniteleridir. 6. dekad ve
sonrasında, kadınlarda daha sık gözlenmektedir. Çoğu asemptomatik olmakla beraber semptomatik olanlar
genellikle sağ üst kadran ağrısı, sarılık, kilo kaybı semptomları ile başvururlar. Görüntüleme bulguları sıklık
sırasına göre; kese lojunu dolduran kitle, fokal ya da diffüz duvar kalınlaşması ve luminal kitledir. En sık
görülen tip (%85 üzeri) adenokarsinomdur. Geri kalanlar skuamöz/adenoskuamöz, undiferansiye ve diğer
başlığı altında toplanabilir. Genellikle geç tanı konması sebebiyle prognoz kötüdür. Olguların çoğunun
asemptomatik olması, semptomatik olanların diğer benign safra yolu hastalıkları ile benzerlik
göstermesinden dolayı tanı gecikmektedir. Görüntüleme bulgularının iyi yorumlanması, klinik hikaye ile
birleştirilerek erken tanı konması, prognozu kötü olan bu kanser tipinde sağkalıma katkı sağlayacaktır.
Anahtar Kelimeler
Safra kesesi Safra kesesi tümörleri Skuamöz hücreli karsinom
Kaynakça
- 1.Yadav R, Jain D, Mathur SR, Sharma A, Iyer VK. Gallbladder carcinoma: An attempt of WHO classification on fine needle aspiration material. CytoJournal 2013;18(10):12
- 2.Roohalamini SA, Tehrani NS, Razavi MK, Au AH, Hansen GC, Ostrzega N, Verma RC. Imagig of gallbladder carcinoma. Radiographics 1994;14(2):291- 306
- 3.Furlan A, Ferris JV, Hosseinzadeh K, Borhani AA. Gallbladder carcinoma update: Multimodality imaging evaluation, staging and treatment options. Am J Roentgenol 2008; 191(5):1440-7
- 4.Kim MJ, Kim KW, Kim HC, Kim SY, Park SH, Kim AY et al. Unusual malignant tumors of the gallbladder. Am J Roentgenol 2006;187(2):473-80
- 5.Wibbenmeyer LA, Sharafuddin MJA, Wolverson MK, Heiberg EV, Wade TP, Shields JB. Sonographic diagnosis of unsuspected gallbladder cancer: İmaging findings in comparison with benign gallbladder conditions. Am J Roentgenol 1995;165(5):1169-74
- 6.Gupta S, Jauhari RK. Rare presentaiton of porcelain gallbladder: carcinoma gallbladder with a large intraabdominal cystic swelling. BMJ Case Rep. 2012;12:2012
- 7.Ansari S. Porcelain gallbladder. Indian J Gastroenterol 2013;33(4):399
- 8.Kim JH, Kim WH, Yoo BM, Kim JH, Kim MW. Should we perform surgical management in all patients with suspected porcelain gallbladder? Hepatogastroenterology. 2009;56:943-5
- 9.Smathers RL, Lee JK, Heiken JP. Differentiationof complicated cholecystitis from gallbladder carcinoma by computed tomography. Am J Roentgenol 1984;143(2):255- 9
- 10.Parra JA, Acinas O, Bueno J, Guemez A, Fernandez MA, Farinas MC. Xanthogranulomatous cholecystitis: Clinical, sonographic and CT findings in 26 patients. Am j Roentgenol 2000;174(4):979-83
- 11.Grand D, Horton KM, Fishman EK. CT of gallbladder: spectrum of disease. Am J Roentgenol 2004;183(1):163-70
An Uncommon Variant Of Gallbladder Cancer On The Basis Of Porcelain Gallbladder; Squamous Cell Cancer
Öz
Our goal is to review gallbladder cancer (GBC) approach accompanied by radiological findings of the case of
th
squamous cell gallbladder cancer on the basis of porcelain gallbladder and the literature. GBC is the 5 most
common gastrointestinal tumors and the most common malignancy of the bile ducts. GBC observed after the
6. decades and more frequently seen among females. Although most cases of asymptomatic, symptomatic
ones are usually refers with right upper quadrant pain, jaundice and weight loss. Imaging findings in order of frequency are the mass that fills the gallbladder fossa, focal or diffuse thickening of the wall and luminal
polypoid mass. The most common type is adenocarcinoma (above 85%). The rest can be grouped under the
title of squamous/adenosquamous, undifferentiated and the others. The diagnosis delayed, because most of
the cases are asymptomatic and the symptomatic ones have similarities with other benign biliary tract
diseases. Generally, the prognosis is poor due to late diagnosis. With good interpretation of imaging findings
and combined with the clinical story, early diagnosis should be made and it will be contribute to the survival
in this type of poor prognosis cancer.
Anahtar Kelimeler
Kaynakça
- 1.Yadav R, Jain D, Mathur SR, Sharma A, Iyer VK. Gallbladder carcinoma: An attempt of WHO classification on fine needle aspiration material. CytoJournal 2013;18(10):12
- 2.Roohalamini SA, Tehrani NS, Razavi MK, Au AH, Hansen GC, Ostrzega N, Verma RC. Imagig of gallbladder carcinoma. Radiographics 1994;14(2):291- 306
- 3.Furlan A, Ferris JV, Hosseinzadeh K, Borhani AA. Gallbladder carcinoma update: Multimodality imaging evaluation, staging and treatment options. Am J Roentgenol 2008; 191(5):1440-7
- 4.Kim MJ, Kim KW, Kim HC, Kim SY, Park SH, Kim AY et al. Unusual malignant tumors of the gallbladder. Am J Roentgenol 2006;187(2):473-80
- 5.Wibbenmeyer LA, Sharafuddin MJA, Wolverson MK, Heiberg EV, Wade TP, Shields JB. Sonographic diagnosis of unsuspected gallbladder cancer: İmaging findings in comparison with benign gallbladder conditions. Am J Roentgenol 1995;165(5):1169-74
- 6.Gupta S, Jauhari RK. Rare presentaiton of porcelain gallbladder: carcinoma gallbladder with a large intraabdominal cystic swelling. BMJ Case Rep. 2012;12:2012
- 7.Ansari S. Porcelain gallbladder. Indian J Gastroenterol 2013;33(4):399
- 8.Kim JH, Kim WH, Yoo BM, Kim JH, Kim MW. Should we perform surgical management in all patients with suspected porcelain gallbladder? Hepatogastroenterology. 2009;56:943-5
- 9.Smathers RL, Lee JK, Heiken JP. Differentiationof complicated cholecystitis from gallbladder carcinoma by computed tomography. Am J Roentgenol 1984;143(2):255- 9
- 10.Parra JA, Acinas O, Bueno J, Guemez A, Fernandez MA, Farinas MC. Xanthogranulomatous cholecystitis: Clinical, sonographic and CT findings in 26 patients. Am j Roentgenol 2000;174(4):979-83
- 11.Grand D, Horton KM, Fishman EK. CT of gallbladder: spectrum of disease. Am J Roentgenol 2004;183(1):163-70
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 28 Nisan 2016 |
| Gönderilme Tarihi | 18 Ekim 2015 |
| Kabul Tarihi | 3 Aralık 2015 |
| Yayımlandığı Sayı | Yıl 2016 Cilt: 13 Sayı: 1 |
Harran Üniversitesi Tıp Fakültesi Dergisi / Journal of Harran University Medical Faculty