Araştırma Makalesi
Yıl 2019,
Cilt: 4 Sayı: 4, 97 - 106, 31.12.2019
Öz
Kaynakça
- 1. Force ADT, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012; 307: 2526-33.2. Dowdy DW, Eid MP, Dennison CR, Mendez-Tellez PA, Herridge MS, Guallar E, et al. Quality of life after acute respiratory distress syndrome: a meta-analysis.Intensive Care Med. 2006;32:1115-24. 3. Brun-Buisson C, Minelli C, Bertolini G, Brazzi L, Pimentel J, Lewandowski K, et al. Epidemiology and outcome of acute lung injury in European intensive care units. Intensive Care Med. 2004;30:51-61.4. Ware LB, Matthay MA. The Acute Respiratory Distress Syndrome. N Engl J Med. 2000; 342:1334-1349. 5. Mikkelsen ME, Shah CV, Meyer NJ, Gaieski DF, Lyon S, Miltiades AN, et al. The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis. Shock. 2013;40:375-381. 6. Li W, Ai X, Ni Y, Ye Z, Liang Z. The association between the neutrophil-to-lymphocyte ratio and mortality in patients with acute respiratory distress syndrome: a retrospective cohort study. Shock. 2019;51:161-167.7. Wang Y, Ju M, Chen C, Yang D, Hou D, Tang X, et al. Neutrophil-to-lymphocyte ratio as a prognostic marker in acute respiratory distress syndrome patients: a retrospective study. J Thorac Dis. 2018;10:273-282.8. Becchi C, Al Malyan M, Fabbri LP, Marsili M, Boddi V, Boncinelli S. Mean platelet volume trend in sepsis: is it a useful parameter? Minerva Anestesiol. 2006;72: 749–756. 9. Canpolat FE, Yurdakök M, Armangil D, Yigit S. Mean platelet volume in neonatal respiratory distress syndrome. Pediatr Int. 2009;51: 314–316. 10. Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. J Thromb Haemost. 2010;8: 148–156. 11. Kostrubiec M, Łabyk A, Pedowska-Włoszek J, Hrynkiewicz-Szyman´ska A, Pacho S, Jankowski K, et al. Mean platelet volume predicts early death in acute pulmonary embolism. Heart. 2010;96: 460–465. 12. Onder I, Topcu S, Dokmetas HS, Turkay C, Seyfikli Z. Platelet aggregation size and volume in chronic obstructive pulmonary disease. Mater Med Pol.1997;29: 11–13.13.Sezgi C, Taylan M, Kaya H, Selimoglu Sen H, Abakay O, Demir M, et al. Alterations in platelet count and mean platelet volume as predictors of patient outcome in the respiratory intensive care unit. Clin Respir J. 2015;9:403-408.14. Felker GM, Allen LA, Pocock SJ, Shaw LK, McMurray JJ, Pfeffer MA, et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank. J Am Coll Cardiol. 2007; 50:40–47.15. Jo YH, Kim K, Lee JH, Kang C, Kim T, Park HM, et al. Red cell distribution width is a prognostic factor in severe sepsis and septic shock. Am J Emerg Med. 2013;31:545-548. 16. Zorlu A, Bektasoglu G, Guven FMK, Dogan OT, Kucuk E, Ege MR , et al . Usefulness of admission red cell distribution width as a predictor of early mortality in patients with acute pulmonary embolism. Am J Cardiol. 2012;109:128-134.17. Bazick HS, Chang D, Mahadevappa K, Gibbons FK, Christopher KB. Red Cell Distribution Width and all cause mortality in critically ill patients. Crit Care Med. 2011;39:1913-1921.18. Jozwiak M, Teboul JL, Monnet X. Extravascular lung water in critical care: recent advances and clinical applications. Ann Intensive Care. 2015;5:38.19. Headley AS, Meduri GU, Tolley E. Infections and the Inflammatory Response in Acute Respiratory Distress Syndrome. Chest. 1997;111:1306-1321.20. Bos LD, Schouten LR, van Vught LA, Wiewel MA, Ong DSY, Cremer O, et al. Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis. Thorax. 2017; 72:876-883.21. Binnie A, Tsang JL, dos Santos CC. Biomarkers in acute respiratory distress syndrome. Curr Opin Crit Care. 2014;20:47-55. 22. Park Y, Schoene N, Haris W. Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets. 2002;13:301-306.23. Kamath S, Blann AD, Lip GY. Platelet activation: assessment and quantification. Eur Heart J. 2001;22:1561-1571.24. Iannacone M. Platelet-mediated modulation of adaptive immunity. Semin Immunol. 2016;28:555-560.25. Zhang Z, Xu X, Ni H, Deng H. Platelet indices are novel predictors of hospital mortality in intensive care unit patients. J Crit Care. 2014; 29: 885.e1-6.26. Perlstein TS, Weuve J, Pfeffer MA, Beckman JA. Red blood cell distribution width and mortality risk in a community-based prospective cohort. Arch Intern Med. 2009;169:588–594.27. Xiao CH, Wan J, Liu H, Qiu L, Wang F, Liu S, Lü XW, Chen XL. Red blood cell distribution width is an independent risk factor in the prediction of acute respiratory distress syndrome after severe burns. Burns. 2019; pii: S0305-4179(18)30924-0.28. Imtiaz F, Shafique K, Mirza SS, Ayoob Z , Vart P , Rao S. Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population. Int Arch Med. 2012;5:2.29. Zahorec R. Ratio of neutrophil to lymphocyte counts-rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102:5-14.30. de Jager CPC, van Wijk PTL, Mathoera RB, de Jongh-Leuvenink J, van der Poll T, Wever PC. Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit. Crit Care. 2010;14(5):R192. 31. Papa A, Emdin M, Passino C, Michelassi C, Battaglia D, Cocci F. Predictive value of elevated neutrophil–lymphocyte ratio on cardiac mortality in patients with stable coronary artery disease. Clin Chim Acta. 2008;395:27-31.32.Cedrés S, Torrejon D, Martinez A, Martinez P, Navarro A, Zamora E, et al. Neutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancer. Clin Transl Oncol. 2012;14:864-869.33. Walsh SR, Cook E, Goulder F, Justin TA, Keeling NJ. Neutrophil lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol. 2005;91:181-184.34. Han Y, Kim SJ, Lee SH, Sim YS, Ryu YJ, Chang JH, et al. High blood neutrophil-lymphocyte ratio associated with poor outcomes in miliary tuberculosis. J Thorac Dis. 2018;10:339-346.35. Kolls JK. Oxidative stress in sepsis: a redox redux. J Clin Invest. 2006;116:860–863.
Do Mean Platelet Volume and Red Cell Distribution Width Predict Mortality in Patients with Acute Respiratory Distress Syndrome?
Öz
Background:
To investigate the role of mean platelet
volume (MPV), red cell distribution width (RDW) and other parameters of
complete blood count on predicting mortality in patients withacute respiratory
distress syndrome (ARDS).
Methods:
Forty-six patients admitted to the
intensive care unit of our institute -a tertiary center- with ARDS between
April 2016 and January 2019 were retrospectively recruited in the study. Demographic
and clinical data including age, gender, accompanying chronic diseases, the
Acute Physiology and Chronic Health Evaluation (APACHE) scores and laboratory
test results were retrospectively collected from medical records and electronic
databases. The study population was divided into two groups according to the
development of mortality as survivors or non-survivors.
Results:
Twenty-five subjects died during the
in-hospital course (non-survivors) and 21 survived (survivors). APACHE II
scores, MPV, RDW
andneutrophil–lymphocyte ratio (NLR) were significantly higher in the
non-survivors group compared to that of the survivors. Multiple logistic
regression analysis revealed that MPV and RDW were independent predictors of
mortality in patients with ARDS. ROC
curve analysis indicated a cut-off value of 8.11 fl for MPV (sensitivity 88%, specificity86%)
and 14.45 % for RDW (sensitivity 84%, specificity86 %) to predict mortality in
patients with ARDS.
Conclusions:
MPV, as an emerging indicator of
preexisting inflammation, and RDW indicating inflammation, independently
predict mortality in patients with ARDS. Implementation of MPV and RDW might be
useful in identifying patients who will require advanced support during admission
for ARDS.
Anahtar Kelimeler
Acute respiratory distress syndrome mean platelet volume red blood cell distribution width
Kaynakça
- 1. Force ADT, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012; 307: 2526-33.2. Dowdy DW, Eid MP, Dennison CR, Mendez-Tellez PA, Herridge MS, Guallar E, et al. Quality of life after acute respiratory distress syndrome: a meta-analysis.Intensive Care Med. 2006;32:1115-24. 3. Brun-Buisson C, Minelli C, Bertolini G, Brazzi L, Pimentel J, Lewandowski K, et al. Epidemiology and outcome of acute lung injury in European intensive care units. Intensive Care Med. 2004;30:51-61.4. Ware LB, Matthay MA. The Acute Respiratory Distress Syndrome. N Engl J Med. 2000; 342:1334-1349. 5. Mikkelsen ME, Shah CV, Meyer NJ, Gaieski DF, Lyon S, Miltiades AN, et al. The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis. Shock. 2013;40:375-381. 6. Li W, Ai X, Ni Y, Ye Z, Liang Z. The association between the neutrophil-to-lymphocyte ratio and mortality in patients with acute respiratory distress syndrome: a retrospective cohort study. Shock. 2019;51:161-167.7. Wang Y, Ju M, Chen C, Yang D, Hou D, Tang X, et al. Neutrophil-to-lymphocyte ratio as a prognostic marker in acute respiratory distress syndrome patients: a retrospective study. J Thorac Dis. 2018;10:273-282.8. Becchi C, Al Malyan M, Fabbri LP, Marsili M, Boddi V, Boncinelli S. Mean platelet volume trend in sepsis: is it a useful parameter? Minerva Anestesiol. 2006;72: 749–756. 9. Canpolat FE, Yurdakök M, Armangil D, Yigit S. Mean platelet volume in neonatal respiratory distress syndrome. Pediatr Int. 2009;51: 314–316. 10. Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. J Thromb Haemost. 2010;8: 148–156. 11. Kostrubiec M, Łabyk A, Pedowska-Włoszek J, Hrynkiewicz-Szyman´ska A, Pacho S, Jankowski K, et al. Mean platelet volume predicts early death in acute pulmonary embolism. Heart. 2010;96: 460–465. 12. Onder I, Topcu S, Dokmetas HS, Turkay C, Seyfikli Z. Platelet aggregation size and volume in chronic obstructive pulmonary disease. Mater Med Pol.1997;29: 11–13.13.Sezgi C, Taylan M, Kaya H, Selimoglu Sen H, Abakay O, Demir M, et al. Alterations in platelet count and mean platelet volume as predictors of patient outcome in the respiratory intensive care unit. Clin Respir J. 2015;9:403-408.14. Felker GM, Allen LA, Pocock SJ, Shaw LK, McMurray JJ, Pfeffer MA, et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank. J Am Coll Cardiol. 2007; 50:40–47.15. Jo YH, Kim K, Lee JH, Kang C, Kim T, Park HM, et al. Red cell distribution width is a prognostic factor in severe sepsis and septic shock. Am J Emerg Med. 2013;31:545-548. 16. Zorlu A, Bektasoglu G, Guven FMK, Dogan OT, Kucuk E, Ege MR , et al . Usefulness of admission red cell distribution width as a predictor of early mortality in patients with acute pulmonary embolism. Am J Cardiol. 2012;109:128-134.17. Bazick HS, Chang D, Mahadevappa K, Gibbons FK, Christopher KB. Red Cell Distribution Width and all cause mortality in critically ill patients. Crit Care Med. 2011;39:1913-1921.18. Jozwiak M, Teboul JL, Monnet X. Extravascular lung water in critical care: recent advances and clinical applications. Ann Intensive Care. 2015;5:38.19. Headley AS, Meduri GU, Tolley E. Infections and the Inflammatory Response in Acute Respiratory Distress Syndrome. Chest. 1997;111:1306-1321.20. Bos LD, Schouten LR, van Vught LA, Wiewel MA, Ong DSY, Cremer O, et al. Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis. Thorax. 2017; 72:876-883.21. Binnie A, Tsang JL, dos Santos CC. Biomarkers in acute respiratory distress syndrome. Curr Opin Crit Care. 2014;20:47-55. 22. Park Y, Schoene N, Haris W. Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets. 2002;13:301-306.23. Kamath S, Blann AD, Lip GY. Platelet activation: assessment and quantification. Eur Heart J. 2001;22:1561-1571.24. Iannacone M. Platelet-mediated modulation of adaptive immunity. Semin Immunol. 2016;28:555-560.25. Zhang Z, Xu X, Ni H, Deng H. Platelet indices are novel predictors of hospital mortality in intensive care unit patients. J Crit Care. 2014; 29: 885.e1-6.26. Perlstein TS, Weuve J, Pfeffer MA, Beckman JA. Red blood cell distribution width and mortality risk in a community-based prospective cohort. Arch Intern Med. 2009;169:588–594.27. Xiao CH, Wan J, Liu H, Qiu L, Wang F, Liu S, Lü XW, Chen XL. Red blood cell distribution width is an independent risk factor in the prediction of acute respiratory distress syndrome after severe burns. Burns. 2019; pii: S0305-4179(18)30924-0.28. Imtiaz F, Shafique K, Mirza SS, Ayoob Z , Vart P , Rao S. Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population. Int Arch Med. 2012;5:2.29. Zahorec R. Ratio of neutrophil to lymphocyte counts-rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102:5-14.30. de Jager CPC, van Wijk PTL, Mathoera RB, de Jongh-Leuvenink J, van der Poll T, Wever PC. Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit. Crit Care. 2010;14(5):R192. 31. Papa A, Emdin M, Passino C, Michelassi C, Battaglia D, Cocci F. Predictive value of elevated neutrophil–lymphocyte ratio on cardiac mortality in patients with stable coronary artery disease. Clin Chim Acta. 2008;395:27-31.32.Cedrés S, Torrejon D, Martinez A, Martinez P, Navarro A, Zamora E, et al. Neutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancer. Clin Transl Oncol. 2012;14:864-869.33. Walsh SR, Cook E, Goulder F, Justin TA, Keeling NJ. Neutrophil lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol. 2005;91:181-184.34. Han Y, Kim SJ, Lee SH, Sim YS, Ryu YJ, Chang JH, et al. High blood neutrophil-lymphocyte ratio associated with poor outcomes in miliary tuberculosis. J Thorac Dis. 2018;10:339-346.35. Kolls JK. Oxidative stress in sepsis: a redox redux. J Clin Invest. 2006;116:860–863.
Toplam 1 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | İç Hastalıkları |
| Bölüm | Araştırma Makaleleri |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Aralık 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 4 Sayı: 4 |
Kaynak Göster
Creative Commons Attribution Non-Commercial License: The articles in the Journal of Immunology and Clinical Microbiology are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.