Öz
Disgerminom, dev boyutlara ulaşabilen overin en sık görülen malign
tümörüdür. Genelde hormon salgılamamakla beraber beta-HCG salgılayabilirler. Bizde
karında kitle ve karın ağrısı şikâyetleri olan radyolojik görüntüleme ile
tespit edilen beta-HCG salgılayan dev boyutlara ulaşmış disgerminom tanılı 3
olguyu inceledik. Üç olguya da salpingo-ooferektomi
ameliyatı yapıldı. Bir olguda komsu lenf nodlarından, peritondan ve karşı
overden örnekleme yapıldı. Bir olgu da üç haftada bir dört kür BEP (Bleomisin, Etoposid, Sisplatin)
kemoterapi protokolü ile fertilite de korunarak tedavi sağlanmış oldu. Bir
olguda da 3 kür BEP kemoterpi protokülü verilmesi planlandı ve 2 kür BEP
kemoterapi protokolü verildi.
Anahtar Kelimeler
Kaynakça
- 1. Akyüz C, Varan A, Büyükpamukçu N, Kutluk T, Büyükpamukçu M. Malignant ovarian tumors in children: 22 years of experience at a single institution. J Pediatr Hematol Oncol 2000; 22:422-7.2. Fotiou SK. Ovarian malignancies in adolescence. Ann N Y Acad Sci 1997;816:338-3463. Zaloudek CJ, Tavassoli FA, Norris DJ. Dysgerminoma with syncytiotrophoblastic giant cells: a histologically and clinically distinctive subtype of dysgerminoma. Am J Surg Pathol 1981;5:361-7.4. Lanzkowsky P. Manual of pediatric hematology and oncology. Elsevier Inc California 4th ed. 2005:652-5.5. Williams SD, Gershenson DM, Horowitz CJ, Silva E. Ovarian germ cell tumors. In eds. Hoskins WJ, Perez CA, Young RC. Principles and practice of gynecologic oncology. III. th edition. 2000, Philadelphia, Lippincott. Williams and Wilkins Company, 1059-1074.6. Tsai JY, Saigo PE, Brown C, La Quaglia MP. Diagnosis, pathology, staging, treatment, and outcome of epithelial ovarian neoplasia in patients age < 21 years. Cancer 2001;91:2065-2070.7. Imai A, Furui T, Tamaya T. Gynecologic tumors and symptoms in childhood and adolescence; 10-years' experience. Int J Gynaecol Obstet 1994;45:227-2348. Deprest J, Moerman P, Corneillie P, Ide P. Ovarian borderline mucinous tumor in a premenarchal girl: review on ovarian epithelial cancer in young girls. Gynecol Oncol 1992;45:219-224.
Öz
Disgerminoma
is the most common malign tumor of the ovary that can reach giant sizes. In
general, although they do not secrete hormones, they may secrete hormones, they
may secrete beta-HCG. We have studied 3 cases of disgerminoma that have reached
giant dimensions that secrete beta-HCG detected by radiological imaging, which
caused a complaint of abdominal pain in the abdomen. Salpingo-oophorectomy
was performed in all three cases. In one case, neighboring
lymph nodes, peritoneum and counter-ovary were sampled. In one case, once in
three weeks, four times treatment of BEP (Bleomycn, Etoposide, Cisplatin)
chemotherapy protocol was administered and treatment was provided without
harming fertility. In another case, three treatment BEP chemotherapy protocol
was planned to administer and two treatment BEP chemotherapy protocol was
performed.
Anahtar Kelimeler
Kaynakça
- 1. Akyüz C, Varan A, Büyükpamukçu N, Kutluk T, Büyükpamukçu M. Malignant ovarian tumors in children: 22 years of experience at a single institution. J Pediatr Hematol Oncol 2000; 22:422-7.2. Fotiou SK. Ovarian malignancies in adolescence. Ann N Y Acad Sci 1997;816:338-3463. Zaloudek CJ, Tavassoli FA, Norris DJ. Dysgerminoma with syncytiotrophoblastic giant cells: a histologically and clinically distinctive subtype of dysgerminoma. Am J Surg Pathol 1981;5:361-7.4. Lanzkowsky P. Manual of pediatric hematology and oncology. Elsevier Inc California 4th ed. 2005:652-5.5. Williams SD, Gershenson DM, Horowitz CJ, Silva E. Ovarian germ cell tumors. In eds. Hoskins WJ, Perez CA, Young RC. Principles and practice of gynecologic oncology. III. th edition. 2000, Philadelphia, Lippincott. Williams and Wilkins Company, 1059-1074.6. Tsai JY, Saigo PE, Brown C, La Quaglia MP. Diagnosis, pathology, staging, treatment, and outcome of epithelial ovarian neoplasia in patients age < 21 years. Cancer 2001;91:2065-2070.7. Imai A, Furui T, Tamaya T. Gynecologic tumors and symptoms in childhood and adolescence; 10-years' experience. Int J Gynaecol Obstet 1994;45:227-2348. Deprest J, Moerman P, Corneillie P, Ide P. Ovarian borderline mucinous tumor in a premenarchal girl: review on ovarian epithelial cancer in young girls. Gynecol Oncol 1992;45:219-224.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Olgu Sunumları |
| Yazarlar | |
| Yayımlanma Tarihi | 8 Temmuz 2018 |
| Gönderilme Tarihi | 31 Mart 2018 |
| Kabul Tarihi | 24 Mayıs 2018 |
| Yayımlandığı Sayı | Yıl 2018 Cilt: 13 Sayı: 2 |
