Olgu Sunumu
Yıl 2021,
Cilt: 23 Sayı: 1, 186 - 190, 30.04.2021
Öz
Kalsifiye fibröz tümör, nadir görülen iğsi hücreli bir tümördür. Genelikle insidental olarak saptanır, fakat semptomatik olduğunda tutulum bölgesine göre klinik prezentasyon farklılık gösterir. İntra abdominal bölge, yumuşak doku ve plevra predileksiyonu gösterir. Sıklıkla çocuk ve genç erişkinlerde izlenir. Hücreden fakir fibrokollagenöz stroma zemini, lenfoplazmositik agregatlar ve lenfoid foliküller, distrofik ve/veya psammomatöz kalsifikasyon içeren spesifik histopatolojik özelliklere sahiptir. Az sayıdaki iğsi hücrelerde vimentin ve faktör XIIIa pozitivitesi saptanır. Biz burada insidental olarak saptanan mezenterik kalsifiye fibröz tümör vakasını benign ve malign lezyonlarla klinikopatolojik olarak karışabilmesi, nadir görüldüğü için akla gelmesi zor bir antite olması sebebiyle, literatür bilgisi eşliğinde sunmayı amaçladık.
Anahtar Kelimeler
Kaynakça
- 1. Chorti A, Papavramidis TS, Michalopoulos A. Calcifying fibrous tumor: Review of 157 patients reported in international literature. Medicine. 2016;95(20):e3690.
- 2. Nascimento AF. Calcifying fibrous tumor. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. World Health Organization Classification of Tumours of Soft Tissue and Bone. 5th ed. Lyon, France. IARC Press, 2013:69.
- 3. Rosenthal NS, Abdul-Karim FW. Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Arch Pathol Lab Med. 1988;112(8):798-800.
- 4. Fetsch J, Montgomery E, Meis J. Calcifying fibrous pseudotumor. Am J Surgery Path. 1993;17(5):502-8.
- 5. Prucker J, Salaheddin-Nassr Y, Leidl S. Calcifying fibrous tumor of the terminal ileum mesentery. Medicine (Baltimore). 2018;97(51):e13351.
- 6. Harmankaya İ, Ugras NS, Sekmenli T, Demir F, Köksal Y. Calcified fibrous pseudotumor with Castleman disease. Autops Case Rep. 2018;8(3):e2018033.
- 7. Ma H, Jiang M, Xiao W. A rare stroma-rich variant of hyaline-vascular Castleman’s disease associated with calcifying fibrous pseudotumor. Int J Clin Exp Pathol. 2015;8(3):3362-4.
- 8. Das DK. Psammoma body: a product of dystrophic calcification or of a biologically active process that aims at limiting the growth and spread of tumor? Diagn Cytopathol. 2009;37(7):534-41.
- 9. Cai YF, Wang QX, Ni CJ, Guo GL, Li Q, Wang OC et al. The clinical relevance of psammoma body and Hashimoto thyroiditis in papillary thyroid carcinoma: A large case-control study. Medicine (Baltimore). 2015;94(44):e1881.
- 10. Han J, Daniel JC, Pappas GD. Expression of type VI collagen in psammoma bodies: immunofluorescence studies on two fresh human meningiomas. Acta Cytol. 1996;40(2):177-81.
- 11. Larson BK, Balzer B, Goldwasser J, Dhall D. Calcifying fibrous tumor: An unrecognized IgG4-related disease? APMIS. 2015;123(1):72-6.
- 12. Agaimy A, Bihl MP, Tornillo L, Wünsch PH, Hartmann A, Michal M. Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis. Am J Surg Pathol. 2010;34(2):271-8.
- 13. Tomassen T, Koelsche C, de Leng WWJ, Kommoss FKF, Voijs CMA, Peeters T et al. Calcifying fibrous tumor and inflammatory myofibroblastic tumor are epigenetically related: A comparative genome-wide methylation study. Ann Diagn Pathol. 2019;41:102-5.
- 14. Zhou J, Zhou L, Wu S, Li R, Yang X, Xu H et al. Clinicopathologic study of calcifying fibrous tumor emphasizing different anatomical distribution and favorable prognosis. Biomed Res Int. 2019;2019:5026860.
- 15. Nascimento AF, Ruiz R, Hornick JL, Fletcher CD. Calcifying fibrous 'pseudotumor': clinicopathologic study of 15 cases and analysis of its relationship to inflammatory myofibroblastic tumor. Int J Surg Pathol. 2002;10(3):189-96.
Yıl 2021,
Cilt: 23 Sayı: 1, 186 - 190, 30.04.2021
Öz
Calcifying fibrous tumor is a rare spindle cell tumor. Despite the fact that it is usually detected incidentally, clinical presentation differs according to the region of involvement when it is symptomatic. Calcifying fibrous tumor shows intra-abdominal region, soft tissue and pleural predilection and is frequently seen in children and young adults. It has specific histopathological features, including paucicellular fibrocollagenous stroma, lymphoplasmocytic aggregates and lymphoid follicles, dystrophic and / or psammomatous calcification. Few spindle cells in pauci cellular stroma are immunoreactive for Vimentin and Factor XIIIa. Here in, we aimed to present the case of incidental mesenteric calcifying fibrous tumor with a literature review, as it is a rare entity and can mimic benign and malignant lesions clinicopathologically.
Anahtar Kelimeler
Kaynakça
- 1. Chorti A, Papavramidis TS, Michalopoulos A. Calcifying fibrous tumor: Review of 157 patients reported in international literature. Medicine. 2016;95(20):e3690.
- 2. Nascimento AF. Calcifying fibrous tumor. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. World Health Organization Classification of Tumours of Soft Tissue and Bone. 5th ed. Lyon, France. IARC Press, 2013:69.
- 3. Rosenthal NS, Abdul-Karim FW. Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Arch Pathol Lab Med. 1988;112(8):798-800.
- 4. Fetsch J, Montgomery E, Meis J. Calcifying fibrous pseudotumor. Am J Surgery Path. 1993;17(5):502-8.
- 5. Prucker J, Salaheddin-Nassr Y, Leidl S. Calcifying fibrous tumor of the terminal ileum mesentery. Medicine (Baltimore). 2018;97(51):e13351.
- 6. Harmankaya İ, Ugras NS, Sekmenli T, Demir F, Köksal Y. Calcified fibrous pseudotumor with Castleman disease. Autops Case Rep. 2018;8(3):e2018033.
- 7. Ma H, Jiang M, Xiao W. A rare stroma-rich variant of hyaline-vascular Castleman’s disease associated with calcifying fibrous pseudotumor. Int J Clin Exp Pathol. 2015;8(3):3362-4.
- 8. Das DK. Psammoma body: a product of dystrophic calcification or of a biologically active process that aims at limiting the growth and spread of tumor? Diagn Cytopathol. 2009;37(7):534-41.
- 9. Cai YF, Wang QX, Ni CJ, Guo GL, Li Q, Wang OC et al. The clinical relevance of psammoma body and Hashimoto thyroiditis in papillary thyroid carcinoma: A large case-control study. Medicine (Baltimore). 2015;94(44):e1881.
- 10. Han J, Daniel JC, Pappas GD. Expression of type VI collagen in psammoma bodies: immunofluorescence studies on two fresh human meningiomas. Acta Cytol. 1996;40(2):177-81.
- 11. Larson BK, Balzer B, Goldwasser J, Dhall D. Calcifying fibrous tumor: An unrecognized IgG4-related disease? APMIS. 2015;123(1):72-6.
- 12. Agaimy A, Bihl MP, Tornillo L, Wünsch PH, Hartmann A, Michal M. Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis. Am J Surg Pathol. 2010;34(2):271-8.
- 13. Tomassen T, Koelsche C, de Leng WWJ, Kommoss FKF, Voijs CMA, Peeters T et al. Calcifying fibrous tumor and inflammatory myofibroblastic tumor are epigenetically related: A comparative genome-wide methylation study. Ann Diagn Pathol. 2019;41:102-5.
- 14. Zhou J, Zhou L, Wu S, Li R, Yang X, Xu H et al. Clinicopathologic study of calcifying fibrous tumor emphasizing different anatomical distribution and favorable prognosis. Biomed Res Int. 2019;2019:5026860.
- 15. Nascimento AF, Ruiz R, Hornick JL, Fletcher CD. Calcifying fibrous 'pseudotumor': clinicopathologic study of 15 cases and analysis of its relationship to inflammatory myofibroblastic tumor. Int J Surg Pathol. 2002;10(3):189-96.
Toplam 15 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 30 Nisan 2021 |
| Gönderilme Tarihi | 13 Ekim 2020 |
| Yayımlandığı Sayı | Yıl 2021 Cilt: 23 Sayı: 1 |
Kaynak Göster
Bu Dergi, Kırıkkale Üniversitesi Tıp Fakültesi Yayınıdır.