Öz
Akut böbrek hasarı (ABH), böbrek fonksiyonlarında ani bozulma, kan üre nitrojeni (BUN) ve serum kreatinin düzeyinde artış, hiperkalemi, metabolik asidoz ve hipertansiyon ile karakterize klinik bir durumdur. ABH tanımlanırken, serum kreatinin düzeyi ve idrar miktarına göre belirlenen kriterlerden oluşan güncel kılavuzlar kullanılmaktadır. ABH'nın üç ana nedeni vardır; prerenal, renal ve postrenal. Prerenal ABH, çocuklarda en sık görülen etyolojidir. ABH'nın klinik semptomları etiyolojiye göre farklılık gösterir. ABH'li bir çocuğu değerlendirirken, kreatinin düzeyindeki artışın tipik olarak böbrek hasarından 48 saat sonra meydana geldiği ve 2-3 gün önceki olayların sonucu olduğu unutulmamalıdır. ABH'nın prognozu etyolojiye göre değişiklik göstermektedir.
Anahtar Kelimeler
Kaynakça
- 1. Whyte DA, Fine RN. Acute renal failure in children. Pediatr Rev. 2008;29(9):299-306; quiz 306-7. doi: 10.1542/pir.29-9-299.
- 2. Bellomo R, Kellum JA, Ronco C. Acute kidney injury. Lancet. 2012;380(9843):756-66. doi: 10.1016/S0140-6736(11)61454-2.
- 3. Behrman RE, Kliegman RM, Jenson HB (2019) Nelson textbook of pediatrics, 21th edn. Saunders, Philadelphia, pp 1818-1822
- 4. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute Dialysis Quality Initiative workgroup. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8(4):R204-12. doi: 10.1186/cc2872.
- 5. Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL. Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int. 2007;71(10):1028-35. doi: 10.1038/sj.ki.5002231.
- 6. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG et al. Acute Kidney Injury Network. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11(2):R31. doi: 10.1186/cc5713.
- 7. Kellum JA, Lameire N, Aspelin P, Barsoum RS, Burdmann EA, Goldstein SL et al. Kidney disease: Improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney International Supplements. 2012;2(1):1-138. doi: 10.1038/kisup.2012.1
- 8. Selewski DT, Symons JM. Acute kidney injury. Pediatr Rev. 2014;35(1):30-41. doi: 10.1542/pir.35-1-30.
- 9. Devarajan P. Emerging biomarkers of acute kidney injury. Contrib Nephrol. 2007;156:203-12. doi: 10.1159/000102085.
- 10. Andreoli SP. Acute kidney injury in children. Pediatr Nephrol. 2009;24(2):253-63. doi: 10.1007/s00467-008-1074-9.
Öz
Acute kidney injury (AKI) is a clinical condition characterized by sudden deterioration in kidney functions, increase in blood urea nitrogen (BUN) and serum creatinine levels, hyperkalemia, metabolic acidosis and hypertension. When defining AKI, current guidelines that consist of criterias determined by serum creatinine level and urine output are used. There are three main causes of AKI; prerenal, renal and postrenal. Prerenal AKI is most common etiology in children. Clinical symptoms of AKI vary depending on etiology. When evaluating a child with AKI, it should be noted that an increase in creatinine typically occurs 48 hours after renal injury and is the result of events 2-3 days earlier. The prognosis of AKI varies depending on the etiology.
Anahtar Kelimeler
Kaynakça
- 1. Whyte DA, Fine RN. Acute renal failure in children. Pediatr Rev. 2008;29(9):299-306; quiz 306-7. doi: 10.1542/pir.29-9-299.
- 2. Bellomo R, Kellum JA, Ronco C. Acute kidney injury. Lancet. 2012;380(9843):756-66. doi: 10.1016/S0140-6736(11)61454-2.
- 3. Behrman RE, Kliegman RM, Jenson HB (2019) Nelson textbook of pediatrics, 21th edn. Saunders, Philadelphia, pp 1818-1822
- 4. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute Dialysis Quality Initiative workgroup. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8(4):R204-12. doi: 10.1186/cc2872.
- 5. Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL. Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int. 2007;71(10):1028-35. doi: 10.1038/sj.ki.5002231.
- 6. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG et al. Acute Kidney Injury Network. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11(2):R31. doi: 10.1186/cc5713.
- 7. Kellum JA, Lameire N, Aspelin P, Barsoum RS, Burdmann EA, Goldstein SL et al. Kidney disease: Improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney International Supplements. 2012;2(1):1-138. doi: 10.1038/kisup.2012.1
- 8. Selewski DT, Symons JM. Acute kidney injury. Pediatr Rev. 2014;35(1):30-41. doi: 10.1542/pir.35-1-30.
- 9. Devarajan P. Emerging biomarkers of acute kidney injury. Contrib Nephrol. 2007;156:203-12. doi: 10.1159/000102085.
- 10. Andreoli SP. Acute kidney injury in children. Pediatr Nephrol. 2009;24(2):253-63. doi: 10.1007/s00467-008-1074-9.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Nefroloji, Klinik Tıp Bilimleri (Diğer) |
| Bölüm | Editöryal |
| Yazarlar | |
| Yayımlanma Tarihi | 30 Nisan 2024 |
| Gönderilme Tarihi | 26 Mart 2024 |
| Kabul Tarihi | 23 Nisan 2024 |
| Yayımlandığı Sayı | Yıl 2024 Cilt: 8 Sayı: 1 |
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