The antibacterial and antifungal activities of herbal oils and their derivatives has been studied for several years; however, more studies are needed to develop al- ternative strategies to destroy pathogenic microorganisms due to increasing con- cerns about the development of antimicrobial resistance amongst them. In this study, our aim was to investigate the minimal inhibitory concentrations (MIC) of 23 different commercially available herbal oils on both yeasts and bacteria strains. Twenty three commercially available herbal oils including centaury, gin- ger, curcumin, eucalyptus, black cumin, cinnamon, sesame, rosemary, safflow- er, cardamom, argan, thyme, etc. were used to determine the antibacterial and antifungal activities on both yeasts and bacteria (standard ATCC strains). Candi- da albicans, Candida parapsilosis, Candida glabrata from yeasts, Escherichia coli from gram-negative bacteria, Acinetobacter baumannii from non-fermen- tative bacteria, and Staphylococcus aureus from gram-positive bacteria were selected. The effective MIC values of herbal oils were detected by using re- sazurin microtiter assay plate (REMA) technique. All herbal oils were effective on standard bacteria and yeast strains in different concentrations. The effective concentration ranges of herbal oils on each bacteria and yeast were as following; 15.625-31.25 μg/ml for Candida parapsilosis (ATCC 22019), 15.625-125 μg/ ml for Acinetobacter baumannii (ATCC 49139), 31.25-62.5 μg/ml for Candida albicans (ATCC 14053), Candida glabrata (ATCC 15126), and Staphylococcus aureus (ATCC 29213), 62.5-125 μg/ml for Escherichia coli (ATCC 25923). In conclusion, antimicrobial capacities of some herbal oils that provide alternative solutions to pathogen microorganisms inhibition, which are made more diffi- cult due to widespread resistance to antimicrobial agents, were evaluated in this study. We believe that this study will contribute to other related studies on the identification of herbal oil antimicrobial mechanisms of action.
Antimicrobial activity Herbal oils Minimal inhibitory concentration REMA
Birincil Dil | İngilizce |
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Konular | Sağlık Kurumları Yönetimi |
Bölüm | Clinical Research |
Yazarlar | |
Yayımlanma Tarihi | 6 Nisan 2020 |
Gönderilme Tarihi | 31 Ocak 2020 |
Kabul Tarihi | 16 Şubat 2020 |
Yayımlandığı Sayı | Yıl 2020 Cilt: 37 Sayı: 2 |
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