Abstract
Amaç: Çölyak hastalığı
(gluten duyarlı enteropati), genetik olarak duyarlı kişilerde buğday, arpa,
çavdar ve yulafın içinde bulunan glutene karşı oluşan duyarlılık reaksiyonudur.
Çölyak hastalığında klinik oldukça farklı ve değişken olabilir. Atipik
belirtilerden ötürü çoğu kez tanının akla getirilmemesi nedeniyle başka
hastalıklar düşünülerek gereksiz ve sonuç getirmeyecek araştırmalar, tedaviler
yapılır. Bu çalışmadaki amaç Çölyak Hastalığının belirtilerinin başlangıcından
teşhis konulmasına kadar geçen zamanı belirlemektir.
Gereç ve
Yöntemler: Ankara
Eğitim ve Araştırma Hastanesi Gastroenetroloji polikliniğine başvuran, yaş
sınırı gözetmeksizin toplam 113 Çölyak hastası çalışmaya alındı. Hastalarda
tanı zamanı, tanı öncesi ilk belirtilerin başladığı tarih, belirtiler ve
belirtiler ile tanı arasındaki süre sorgulandı.
Bulgular:
Hastaların
yaş ortalaması 36.83±14.59, belirti başlangıcından tanı anına kadar geçen süre
ortalaması 29.1±57.11 aydı. Erkeklerde tanı için geçen ortalama süre
22.13±36.75 ay iken kadınlarda 32.36±64.54 ay olarak saptandı.
Sonuç: Çölyak Hastalığı
belirti başlangıcından tanı anına kadar geçen süre ortalaması 2.5 yıl olup, erken
ve doğru klinik tanı maddi kazanç yanında gereksiz zaman ve çaba harcanmasını
da engelleyecektir.
References
- Rubio-Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA; American College of Gastroenterology. ACG clinical guidelines: Diagnosis and management of celiac disease. Am J Gastroenterol 2013;108 (5):656-76.
- Demirçeken FG, Kansu A, Kuloğlu Z, Girgin N, Güriz H, Ensari A. Human tissue transglutaminase antibody screening by immunochromatographic line immunoassay for early diagnosis of celiac disease in Turkish children. Turk J Gastroenterol 2008;19(1):14-21.
- Ertekin V, Selimoğlu MA, Kardaş F, Aktaş E. Prevalence of celiac disease in Turkish children. J Clin Gastroenterol 2005;39(8):689-91.
- Gursoy S, Guven K, Simsek T, et al. The prevalence of unrecognized adult celiac disease in Central Anatolia. J Clin Gastroenterol 2005;39(6):508-11.
- Cummins AG, Roberts-Thomson IC. Prevalence of celiac disease in the Asia-Pacific region. J Gastroenterol Hepatol 2009;24(8):1347-51.
- Maki M, Kakkonen K, Lahdeaho ML, Visakorpi JK. Changing pattern of childhood celiac disease in Finland. Acta Paediatr Scand 1988;77(3):408-12.
- Reilly NR, Fasano A, Green PH. Presentation of celiac disease. Gastrointest Endosc Clin N Am 2012;22(4):613-21.
- Balamtekin N, Uslu N, Bayson G, et al. The presentation of celiac disease in 220 Turkish children. Turk J Pediatr 2010;52(3):239-44.
- Ford AC, Ching E, Moayyedi P.Yield of diagnostic tests for coeliac disease in dyspepsia. Aliment Pharmacol Ther 2009;30(1):28-36.
- Cranney A, Zarkadas M, Graham ID, et al. The Canadian celiac health survey. Dig Dis Sci 2007;52(4):1087-95.
- Norström F, Lindholm L, Sandström O, Nordyke K, Ivarsson A. Delay to celiac disease diagnosis and its implications for health-related quality of life. BMC Gastroenterol 2011;11(2):118.
- Sood A, Midha V, Malhotra D, Halli SS. Adult celiac disease: Delayed onset or delayed diagnosis? Ann Gastroenterol 2014;27(3):284.
Abstract
Aim: Celiac Disease
(gluten-sensitive enteropathy. is a sensitivity reaction against gluten in
genetically susceptible individuals induced by the ingestion of wheat, barley,
rye and oats. Clinics can be quite different and variable in Celiac Disease.
Because wide variety of clinical presentations, most patient considered with other
diseases and treatment. The aim of this study is to determine the interval from
the beginning of the symptoms to the time of diagnosis.
Materials
and Methods: This study was conducted with 113 Celiac Disease patients at Ankara
Training and Research Hospital Gastroenterology Polyclinic regardless of the
age limit. The time of diagnosis, symptoms and the length of time from the
start of the symptoms to the time of diagnosis were questioned.
Results: The mean age of the
patients was 36.83 ± 14.59, the mean time from the start of symptoms to the
diagnosis was 29.1 ± 57.11 months and the length of time for diagnosis in males
and women were 22.13 ± 36.75 and 32.36 ± 64.54 months respectively.
Conclusion: The mean duration from the onset of symptoms to the time of diagnosis in
Celiac Disease is 2.5 years. Early and accurate diagnosis of the Celiac Disease
will prevent from unnecessary effort for diagnosis and provide financial gain.
References
- Rubio-Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA; American College of Gastroenterology. ACG clinical guidelines: Diagnosis and management of celiac disease. Am J Gastroenterol 2013;108 (5):656-76.
- Demirçeken FG, Kansu A, Kuloğlu Z, Girgin N, Güriz H, Ensari A. Human tissue transglutaminase antibody screening by immunochromatographic line immunoassay for early diagnosis of celiac disease in Turkish children. Turk J Gastroenterol 2008;19(1):14-21.
- Ertekin V, Selimoğlu MA, Kardaş F, Aktaş E. Prevalence of celiac disease in Turkish children. J Clin Gastroenterol 2005;39(8):689-91.
- Gursoy S, Guven K, Simsek T, et al. The prevalence of unrecognized adult celiac disease in Central Anatolia. J Clin Gastroenterol 2005;39(6):508-11.
- Cummins AG, Roberts-Thomson IC. Prevalence of celiac disease in the Asia-Pacific region. J Gastroenterol Hepatol 2009;24(8):1347-51.
- Maki M, Kakkonen K, Lahdeaho ML, Visakorpi JK. Changing pattern of childhood celiac disease in Finland. Acta Paediatr Scand 1988;77(3):408-12.
- Reilly NR, Fasano A, Green PH. Presentation of celiac disease. Gastrointest Endosc Clin N Am 2012;22(4):613-21.
- Balamtekin N, Uslu N, Bayson G, et al. The presentation of celiac disease in 220 Turkish children. Turk J Pediatr 2010;52(3):239-44.
- Ford AC, Ching E, Moayyedi P.Yield of diagnostic tests for coeliac disease in dyspepsia. Aliment Pharmacol Ther 2009;30(1):28-36.
- Cranney A, Zarkadas M, Graham ID, et al. The Canadian celiac health survey. Dig Dis Sci 2007;52(4):1087-95.
- Norström F, Lindholm L, Sandström O, Nordyke K, Ivarsson A. Delay to celiac disease diagnosis and its implications for health-related quality of life. BMC Gastroenterol 2011;11(2):118.
- Sood A, Midha V, Malhotra D, Halli SS. Adult celiac disease: Delayed onset or delayed diagnosis? Ann Gastroenterol 2014;27(3):284.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | December 3, 2018 |
| Submission Date | October 12, 2017 |
| Published in Issue | Year 2018 |
Cited By
Çölyak Hastaları İçin Meşe Palamudu Meyvesinden Glütensiz Diş Macunu Elde Edilmesi ve Analizi
Afyon Kocatepe University Journal of Sciences and Engineering
https://doi.org/10.35414/akufemubid.1004368