Abstract
Amaç: Tek taraflı okülodermal melanositoz (ODM) hastalarının etkilenmiş gözleri ve karşı taraf normal
gözlerini ön segment parametreleri açısından karşılaştırmak.
Gereç ve Yöntem: Tek taraflı ODM olan hastaların dosyaları ve Scheimpflug kamera ile alınmış
ölçümleri retrospektif olarak incelendi. ODM’li gözler (Grup 1) ve karşı normal gözler (Grup 2) ön
kamara derinliği (ÖKD), ön kamara hacmi (ÖKH), ön kamara açısı (ÖKA) genişliği, santral kornea
kalınlığı (SKK), keratometri, pupilla çapı parametreleri açısından karşılaştırıldı.
Bulgular: Ortalama yaşları 32,50±12,20 (12 ve 48 arası) olan 16 hasta çalışmaya dahil edildi. Gruplar
arasında ÖKD, ÖKH, SKK, keratometri, pupilla çapı değerleri açısından farklılık saptanmadı (sırasıyla,
p=0,655, p=0,812, p=0,131, p=0,434, p=0,325, p=0,509). ÖKA değerleri Grup 1 gözlerde Grup 2
gözlerden daha düşük olmasına rağmen bu fark istatistiksel olarak anlamlı bulunmadı (p=0,057).
Sonuç: İstatistiksel olarak anlamlı olmamakla beraber ÖKA değerleri tek taraflı ODM hastalarının
etkilenmiş gözlerinde karşı taraf normal gözlerden daha dar olma eğilimindedir. Bu konuda daha çok
sayıda hasta ile yapılacak yeni çalışmalara ihtiyaç vardır.
Keywords
References
- 1. Singh AD, De Potter P, Fijal BA, Shields CL, Shields JA, Elston RC. Lifetime prevalence of uveal melanoma in white patients with oculo (dermal) melanocytosis. Ophthalmology. 1998; 105: 195-8.
- 2. Ota M. Nevus fusco-caeruleus ophthalmomaxillaris. Tokyo Med J. 1939; 63: 1243-5.
- 3. Shields JA, Shields CL. Posterior uveal melanoma. In: Shields JA, Shields CL, eds. Intraocular Tumors: A Textbook and Atlas. Philadelphia, PA: Lippincott, Williams & Wilkins; 2008:85-117.
- 4. Shields JA, Shields CL. Congenital oculo(dermal) melanocytosis. In: Shields JA, Shields CL, eds. Intraocular Tumors: A Textbook and Atlas. Philadelphia, PA: Lippincott, Williams & Wilkins; 2008:6-12.
- 5. Teekhasaenee C, Ritch R, Rutnin U, Leelawongs N. Glaucoma in oculodermal melanocytosis. Ophthalmology 1990; 97: 562-70.
- 6. Rabsilber TM, Khoramnia R, Auffarth GU. Anterior chamber measurements using Pentacam rotating Scheimpflug camera. J Cataract Refract Surg 2006; 32: 456- 9.
- 7. Palamar Onay M, Egrilmez S, Üretmen Ö, Köse S. Evaluation of Cornea and Anterior Chamber Using Pentacam in Pediatric Cases. Turk J Ophthalmol 2011; 41: 133-7.
- 8. Palamar M, Egrilmez S, Uretmen O, Yagci A, Kose S. Influences of cyclopentolate hydrochloride on anterior segment parameters with Pentacam in children. Acta Ophthalmologica 2011; 89: e461-e465.
- 9. Palamar M, Alkan Z, Egrilmez S, Yagci A. Influences of tropicamide on anterior segment parameters with Pentacam in healthy individuals. J Ocul Pharmacol Ther 2013; 29: 349-52.
- 10. Gonder JR, Shields JA, Albert DM, Augsburger JJ, Lavin PT. Uveal malignant melanoma associated with ocular and oculodermal melanocytosis. Ophthalmology 1982; 89: 953-60.
- 11.Plateroti AM, Scavella V, Abdolrahimzadeh B, Plateroti R, Rahimi S. An Update on Oculodermal Melanocytosis and Rare Associated Conditions. Semin Ophthalmol. 2016 Apr 15: 1-5.
- 12.Velazquez-Martin JP, Krema H, Fulda E, Yücel YH, Simpson ER, Pavlin CJ. Ultrasound biomicroscopy of the ciliary body in ocular/oculodermal melanocytosis. Am J Ophthalmol 2013; 155: 681-7, 687.e1-2.
Abstract
Aim: To compare the anterior segment parameters of effected and normal eyes of unilateral
oculodermal melanocytosis (ODM) patients.
Materials and Methods: A retrospective chart and Scheimpflug camera database review for unilateral
ODM patients were conducted. Anterior chamber depth (ACD), anterior chamber volume (ACV),
anterior chamber angle (ACA) width, central corneal thickness (CCT), keratometry, pupilla diameter
parameters of the eye with ODM (Group 1) was compared to the normal (Group 2) eye.
Results: Sixteen patients with a mean age of 32.50±12.20 (range 12 and 48) were enrolled. No
difference between groups were detected in terms of ACD, ACV, CCT, keratometry, pupilla diameter
(p=0.655, p=0.812, p=0.131, p=0.434, p=0.325, p=0.509, respectively). Although ACA was lower in
Group 1 the difference was not statistically significant (p=0.057).
Conclusion: Although not statistically significant, there seems to be a tendency for shallow ACA
readings in unilateral ODM eyes when compared to normal contralateral eyes. However, more studies
with larger number of patients that evaluate this issue are needed.
References
- 1. Singh AD, De Potter P, Fijal BA, Shields CL, Shields JA, Elston RC. Lifetime prevalence of uveal melanoma in white patients with oculo (dermal) melanocytosis. Ophthalmology. 1998; 105: 195-8.
- 2. Ota M. Nevus fusco-caeruleus ophthalmomaxillaris. Tokyo Med J. 1939; 63: 1243-5.
- 3. Shields JA, Shields CL. Posterior uveal melanoma. In: Shields JA, Shields CL, eds. Intraocular Tumors: A Textbook and Atlas. Philadelphia, PA: Lippincott, Williams & Wilkins; 2008:85-117.
- 4. Shields JA, Shields CL. Congenital oculo(dermal) melanocytosis. In: Shields JA, Shields CL, eds. Intraocular Tumors: A Textbook and Atlas. Philadelphia, PA: Lippincott, Williams & Wilkins; 2008:6-12.
- 5. Teekhasaenee C, Ritch R, Rutnin U, Leelawongs N. Glaucoma in oculodermal melanocytosis. Ophthalmology 1990; 97: 562-70.
- 6. Rabsilber TM, Khoramnia R, Auffarth GU. Anterior chamber measurements using Pentacam rotating Scheimpflug camera. J Cataract Refract Surg 2006; 32: 456- 9.
- 7. Palamar Onay M, Egrilmez S, Üretmen Ö, Köse S. Evaluation of Cornea and Anterior Chamber Using Pentacam in Pediatric Cases. Turk J Ophthalmol 2011; 41: 133-7.
- 8. Palamar M, Egrilmez S, Uretmen O, Yagci A, Kose S. Influences of cyclopentolate hydrochloride on anterior segment parameters with Pentacam in children. Acta Ophthalmologica 2011; 89: e461-e465.
- 9. Palamar M, Alkan Z, Egrilmez S, Yagci A. Influences of tropicamide on anterior segment parameters with Pentacam in healthy individuals. J Ocul Pharmacol Ther 2013; 29: 349-52.
- 10. Gonder JR, Shields JA, Albert DM, Augsburger JJ, Lavin PT. Uveal malignant melanoma associated with ocular and oculodermal melanocytosis. Ophthalmology 1982; 89: 953-60.
- 11.Plateroti AM, Scavella V, Abdolrahimzadeh B, Plateroti R, Rahimi S. An Update on Oculodermal Melanocytosis and Rare Associated Conditions. Semin Ophthalmol. 2016 Apr 15: 1-5.
- 12.Velazquez-Martin JP, Krema H, Fulda E, Yücel YH, Simpson ER, Pavlin CJ. Ultrasound biomicroscopy of the ciliary body in ocular/oculodermal melanocytosis. Am J Ophthalmol 2013; 155: 681-7, 687.e1-2.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | September 30, 2020 |
| Submission Date | July 24, 2019 |
| Published in Issue | Year 2020 |