Serum hormone levels of children receiving anticonvulsants

Volume: 47 Number: 1 March 1, 2008
  • Yeşiltepe Mutlu G R
  • Vitrinel A
  • Ağzıkuru T
  • Cömert S
  • Edağ G Ç
  • Akın Y
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Serum hormone levels of children receiving anticonvulsants

Abstract

Aim: To determine the effects of anticonvulsants on serum thyroid hormones,prolactin,parathyroid hormone, and calcium,phosphorus,alkaline phosphatase levels. Material - Methods: Seventy three epileptic children receiving anticonvulsants for more than one year were evaluated for serum thyroid hormones,prolactin,parathyroid hormone bone metabolism and compared with control group. Results: Fourty four patients(60.3%)were boys;29 patients(39.7%)girls.Mean age was 6.98±3.34 years.Thirty eight patients(52.1%)were receiving valproic acid,twenty five patients(34.2%)were receiving carbamazepine,eight patients(11%)were receiving phenobarbital and two patients(2.7%)were receiving vigabatrin.Serum free T4 levels were below the normal range in one patient(4%)receiving carbamazepine.Serum free T4 levels were lower and TSH levels were elevated in 2(5.26%)VPA receving patients.Serum parathyroid hormone levels were elevated in three(12%)carbamazepine receiving patients and two(5.3%)VPA receiving patients. Prolactine levels were above the normal range in one patient(2.63%) receiving VPA and four patients (16%)receiving carbamazepine.Serum calcium and phosphorus levels were normal in all control group. Conclusion: There was no significant statistical difference in serum hormone levels and bone metabolism,between study group and control group

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Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Yeşiltepe Mutlu G R

Vitrinel A

Ağzıkuru T

Cömert S

Edağ G Ç

Akın Y

Publication Date

March 1, 2008

Submission Date

March 1, 2008

Acceptance Date

-

Published in Issue

Year 1970 Volume: 47 Number: 1

IZ

https://izlik.org/JA76UH92FR

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1.Yeşiltepe Mutlu G R, Vitrinel A, Ağzıkuru T, Cömert S, Edağ G Ç, Akın Y. Antiepileptik tedavi alan çocuklarda serum hormon düzeyleri. EJM [Internet]. 2008 Mar. 1;47(1):47-50. Available from: https://izlik.org/JA76UH92FR

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