Epidemiological and overall survival characteristics of head and neck cancer patients recorded in the database of Ege University Faculty of Medicine
Abstract
Aim: General demographic characteristics, tumor localization frequency and overall survival according to cancer locations of the patients diagnosed with head and neck tumor located in EU Cancer Control Application and Research Center (EUKAM) were investigated.
Methods: According to the topography code of 6951 head and neck cancer patients registered at Ege University between 1992-2016; diagnosis age, tumor location, histopathology, sex, treatment modalities, latest status, follow-up period were evaluated.
Results: 6549 (94.2%) of our cases were diagnosed as carcinoma, the larynx is the most common site with a rate of 45.3%. Male are 80% of the cases. According to genders, tumor location was mostly in the larynx (57.3%) in males and in the oral cavity (40.6%) in females. Most of the cases were diagnosed in locally limited stage (47.9%). Overall survival at 5 and 10 years was 56% and 48%, respectively. The 5-year survival rate in the larynx and nasopharynx was 61% and 57%, respectively.
Conclusion: Laryngeal cancer is the most common tumor and 5-year overall survival is 61%. Over the years, the number of cases with head and neck tumors continued to increase.
Keywords
Head and neck cancers epidemiology larynx nasopharynx oropharynx hypopharynx oral cavity survival.
References
- Torre LA, Bray F, Siegel RL, ve ark. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87-108.
- Ajayi OF, Adeyemo WL, Ladeinde AL, ve ark. Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital. Int J Oral Maxillofac Surg. 2007;36(5):403-8.
- Effiom OA, Adeyemo WL, Omitola OG, ve ark. Oral squamous cell carcinoma: a clinicopathologic review of 233 cases in Lagos, Nigeria. J Oral Maxillofac Surg. 2008;66(8):1595-9.
- Franceschi S, Bidoli E, Herrero R, Muñoz N. Comparison of cancers of the oral cavity and pharynx worldwide: etiological clues. Oral Oncol. 2000;36(1):106-15.
- Boring CC, Squires TS, Tong T, Montgomery S. Cancer statistics, 1994. CA Cancer J Clin. 1994;44(1):7-26.
- Larizadeh M H, Damghani M A, M. Epidemiological Characteristics of Head and Neck Cancers in Southeast of Iran. Iran J CancerPrev. 2014;7(2):80–6.
- Alvarenga L M, Ruiz M T, Pavarino-Bertelli E C. Epidemiologic evaluation of head and neck patients in a university hospital of Northwestern. SãoPauloStateRev. Bras. Otorrinolaringol. 2008;74(1):68-73.
- Rebecca L. Siegel MPH Kimberly D. Miller MPH Cancer statistics, 2019 CA Cancer J Clin 2019;69:7-34.
- Kara F, İlter H, Keskinkılıç B ve ark. Türkiye Kanser İstatistikleri 2015. Halk Sağlığı Genel Müd. Sağlık Bakanlığı 2018.
- Carvalho AL, Singh B, Spiro RH. Cancer of the oral cavity: a comparison between institutions in a developing and a developed nation. HeadNeck. 2004;26(1):31-8. 2019;Cilt / Volume: 58 (Ek Sayı / Supplement) 119
- Mourad M, Jetmore T, Jategaonkar AA. Epidemiological Trends of Head and Neck Cancer in the United States: A SEER PopulationStudy.J Oral Maxillofac Surg. 2017;75(12):2562-72.
- Gattaa G, Bottaa L, Sánchez M J ve ark. Prognoses and improvement for head and neck cancers diagnosed in Europe in early 2000s: The EUROCARE-5 population-based study. Eur J Cancer. 2015;51(15):2130-43.
- Rettig EM, D'Souza G. Epidemiology of head and neck cancer. Surg Oncol Clin N Am. 2015 Jul;24(3):379-96.
- Lambert R, Sauvaget C, de Camargo Cancela M, Sankaranarayanan R. Epidemiology of cancer from the oral cavity and oropharynx. Eur J Gastroenterol Hepatol. 2011;23(8):633-41.
Ege Üniversitesi Tıp Fakültesi veri tabanında kayıtlı baş-boyun kanserli olguların epidemiyolojik ve genel sağ kalım özellikleri
Abstract
Amaç: Ege Üniversitesi Kanserle Savaş Uygulama ve Araştırma Merkezi’nde (EÜKAM) kayıtlı olan, baş-boyun bölgesi yerleşimli tümör tanısı alan hastaların, genel demografik özellikleri, tümör yerleşim sıklığı, kanser yerleşimlerine göre genel sağ kalımları araştırılmıştır.
Gereç ve Yöntem: EÜKAM’nin kanser kayıt elemanları tarafından kaydedilen 1992-2016 yılları arasında, Ege Üniversitesinde kayıtlı 6951 Baş-Boyun kanserli hasta topografi koduna göre; tanı yaşı, tümör yerleşimi, histopatolojileri, cinsiyetleri, uygulanan tedavi yöntemleri, son durumları, takip süreleri değerlendirilmiştir.
Bulgular: Olgularımızın 6549’u (%94,2) karsinom, larinks %45,3 oranıyla en sık yerleşim yeridir. Olguların %80’i erkektir. Cinsiyetlere göre tümör yerleşim yeri, erkeklerde sıklıkla larinkse (%57,3), kadınlarda oral kavite bölgesine (%40,6) olmuştur. Olguların çoğunlukla lokal sınırlı evrede tanı almışlardır (%47,9). Tüm olgularda beş ve 10 yıllık genel sağ kalım sırasıyla %56, %48’dir. Larinks ve nazofarinks yerleşiminde beş yıllık sağ kalım sırasıyla %61 ve %57 bulunmuştur.
Sonuç: Larinks kanseri en sık görülen tümör olup ve beş yıllık genel sağ kalım %61’dir. Yıllar içinde baş-boyun tümörlü olgu sayısında artış devam etmiştir.
Keywords
Baş-boyun kanserleri epidemiyoloji larinks nazofarinks orofarinks hipofarinks oral kavite sağ kalım.
References
- Torre LA, Bray F, Siegel RL, ve ark. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87-108.
- Ajayi OF, Adeyemo WL, Ladeinde AL, ve ark. Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital. Int J Oral Maxillofac Surg. 2007;36(5):403-8.
- Effiom OA, Adeyemo WL, Omitola OG, ve ark. Oral squamous cell carcinoma: a clinicopathologic review of 233 cases in Lagos, Nigeria. J Oral Maxillofac Surg. 2008;66(8):1595-9.
- Franceschi S, Bidoli E, Herrero R, Muñoz N. Comparison of cancers of the oral cavity and pharynx worldwide: etiological clues. Oral Oncol. 2000;36(1):106-15.
- Boring CC, Squires TS, Tong T, Montgomery S. Cancer statistics, 1994. CA Cancer J Clin. 1994;44(1):7-26.
- Larizadeh M H, Damghani M A, M. Epidemiological Characteristics of Head and Neck Cancers in Southeast of Iran. Iran J CancerPrev. 2014;7(2):80–6.
- Alvarenga L M, Ruiz M T, Pavarino-Bertelli E C. Epidemiologic evaluation of head and neck patients in a university hospital of Northwestern. SãoPauloStateRev. Bras. Otorrinolaringol. 2008;74(1):68-73.
- Rebecca L. Siegel MPH Kimberly D. Miller MPH Cancer statistics, 2019 CA Cancer J Clin 2019;69:7-34.
- Kara F, İlter H, Keskinkılıç B ve ark. Türkiye Kanser İstatistikleri 2015. Halk Sağlığı Genel Müd. Sağlık Bakanlığı 2018.
- Carvalho AL, Singh B, Spiro RH. Cancer of the oral cavity: a comparison between institutions in a developing and a developed nation. HeadNeck. 2004;26(1):31-8. 2019;Cilt / Volume: 58 (Ek Sayı / Supplement) 119
- Mourad M, Jetmore T, Jategaonkar AA. Epidemiological Trends of Head and Neck Cancer in the United States: A SEER PopulationStudy.J Oral Maxillofac Surg. 2017;75(12):2562-72.
- Gattaa G, Bottaa L, Sánchez M J ve ark. Prognoses and improvement for head and neck cancers diagnosed in Europe in early 2000s: The EUROCARE-5 population-based study. Eur J Cancer. 2015;51(15):2130-43.
- Rettig EM, D'Souza G. Epidemiology of head and neck cancer. Surg Oncol Clin N Am. 2015 Jul;24(3):379-96.
- Lambert R, Sauvaget C, de Camargo Cancela M, Sankaranarayanan R. Epidemiology of cancer from the oral cavity and oropharynx. Eur J Gastroenterol Hepatol. 2011;23(8):633-41.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Supplement |
| Authors | |
| Publication Date | December 31, 2019 |
| Submission Date | February 15, 2019 |
| Published in Issue | Year 2019Volume: 58 Suppl: 2 (Oncology) |
