Abstract
Raynaud fenomeni (RF), vücudun distal kısımlarında renk değişiklikleri ve epizodik vazospazm ile karakterizedir. Sensörimotor demiyelinizan polinöropati ile ilişkili RF literatürde nadiren bildirilmiştir. Biz burada üst ve alt ekstremitelerde renk değişikliği, uyuşma, karıncalanma şikayetleri ile kliniğimize başvuran 36 yaşında erkek hastayı sunmayı amaçladık. Hastanın sinir ileti çalışmalarında mikst tip sensorimotor demiyelinizan polinöropati saptandı. Hastada pregabalin, asetilsalisilik asit ve nifedipin tedavisi sonrası 2 ay içinde belirgin düzelme görüldü.
References
- Temprano KK. A Review of Raynaud's Disease.Mo Med. 2016; 113: 123-6.
- Pauling JD, Hughes M, Pope JE. Raynaud's phenomenon-an update on diagnosis, classification and management. Clin Rheumatol. 2019; 38: 3317-30.
- Herrick AL. Pathogenesis of Raynaud’s phenomenon. Rheumatology 2005; 44: 587-96.
- Gunatilake SS, Wimalaratna H. Guillain-Barré syndrome presenting with Raynaud's phenomenon: a case report. BMC Neurol. 2014; 14: 174.
- Manek NJ, Holmgren AR, Sandroni P, Osborn TG, Davis MD. Primary Raynaud phenomenon and small-fiber neuropathy: is there a connection? A pilot neurophysiologic study. Rheumatol Int. 2011; 31: 577-85.
- Garner R, Kumari R, Lanyon P, Doherty M, Zhang W. Prevalence, risk factors and associations of primary Raynaud’s phenomenon: systematic review and meta-analysis of observational studies. BMJ Open. 2015; 5: 6389.
- Devgire V, Hughes M. Raynaud's phenomenon.Br J Hosp Med (Lond). 2019; 80: 658-64.
- Ginsberg L. Acute and chronic neuropathies. Medicine (Abingdon) 2020; 48: 612-8.
- Lacomis D. Small-fiber neuropathy. Muscle Nerve. 2002; 26: 173-88.
Abstract
Raynaud's phenomenon (RP) is characterized by color changes and episodic vasospasm in the distal parts of the body. Raynaud's phenomenon associated with sensorimotor demyelinating polyneuropathy has been rarely reported in the literature. Here, we aimed to present a 36-year-old male patient who was admitted to our clinic with complaints of discoloration, numbness, and tingling in the upper and lower extremities. A mixed type of sensorimotor demyelinating polyneuropathy was detected in nerve conduction studies of the patient. A significant improvement was observed within 2 months after pregabalin, acetylsalicylic acid, and nifedipine treatment.
References
- Temprano KK. A Review of Raynaud's Disease.Mo Med. 2016; 113: 123-6.
- Pauling JD, Hughes M, Pope JE. Raynaud's phenomenon-an update on diagnosis, classification and management. Clin Rheumatol. 2019; 38: 3317-30.
- Herrick AL. Pathogenesis of Raynaud’s phenomenon. Rheumatology 2005; 44: 587-96.
- Gunatilake SS, Wimalaratna H. Guillain-Barré syndrome presenting with Raynaud's phenomenon: a case report. BMC Neurol. 2014; 14: 174.
- Manek NJ, Holmgren AR, Sandroni P, Osborn TG, Davis MD. Primary Raynaud phenomenon and small-fiber neuropathy: is there a connection? A pilot neurophysiologic study. Rheumatol Int. 2011; 31: 577-85.
- Garner R, Kumari R, Lanyon P, Doherty M, Zhang W. Prevalence, risk factors and associations of primary Raynaud’s phenomenon: systematic review and meta-analysis of observational studies. BMJ Open. 2015; 5: 6389.
- Devgire V, Hughes M. Raynaud's phenomenon.Br J Hosp Med (Lond). 2019; 80: 658-64.
- Ginsberg L. Acute and chronic neuropathies. Medicine (Abingdon) 2020; 48: 612-8.
- Lacomis D. Small-fiber neuropathy. Muscle Nerve. 2002; 26: 173-88.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Reports |
| Authors | |
| Publication Date | September 12, 2022 |
| Submission Date | March 29, 2021 |
| Published in Issue | Year 2022Volume: 61 Issue: 3 |
