Year 2019, Volume 58, Issue 2, Pages 126 - 130 2019-06-28

Hemodiyaliz hastalarında dış kulak yolu ve nazal kavitede mikrobiyal kolonizasyon ve antimikrobiyal duyarlılık
Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients

Korhan Kılıç [1] , Eylül Derman [2] , Muhammed Sedat Sakat [3] , Mustafa Sıtkı Gözeler [4] , Hakan Uslu [5] , Furkan Şengöz [6]

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Amaç: Normal bakteriyel floranın bağışıklık üzerindeki etkisi onu mikroorganizmaların zararlı etkilerine karşı daha etkili hale getirmek ve hızlı bir cevap oluşturacak şekilde hazır tutmaktır. Bu çalışmanın amacı hemodiyaliz hastalarında nazal kavite ve dış kulak yolundaki bakteriyel florayı tespit etmek, bunu normal populasyonla karşılaştırmak ve mikroorganizmaların antimikrobiyal duyarlılığını ortaya koymaktı.

Gereç ve Yöntem: Çalışmaya en az 3 yıldır hemodiyaliz alan hastalar dâhil edildi. Herhangi bir immunsupresyon durumu olmayan ve kulak hastalıkları dışı sebeplerle hastaneye başvuran hastalardan da kontrol grubu oluşturuldu (n=62). Tüm katılımcıların nazal kavite ve dış kulak yollarından kültür çubuğu ile kültür örnekleri alındı. Kültür sonuçları ile antimikrobiyal duyarlılık test sonuçları kaydedildi.

Bulgular: Çalışma grubunda dış kulak yolundan en çok izole edilen bakteri MRCoNS (%41) iken bunu MSCoNS (%15,5) ve Difteroidler (%9,8) izlemekteydi. Nazal kaviteden ise en sık izole edilen bakteri CoNS olup (%52,7) bunun %69,2’sini MRCoNS oluşturmaktaydı.

Sonuç: Hemodiyaliz hastalarında mortalite ve morbiditede önemli rol oynayan enfeksiyonların nazal kavite kadar dış kulak yolundan da kaynaklanabileceğini, bu nedenle antimikrobiyal duyarlılık testleri ile belirlenen uygun antibiyoterapi ile bu bölgedeki mikroorganizmaların da elimine edilmesinin önemli olduğunu düşünmekteyiz.

Aim: The effect of normal bacterial flora on the immune system is to make it more effective against harmful micro-organisms and to maintain it in readiness for a more rapid response. The purpose of this study was to determine the bacterial flora in the external ear canal and nasal cavities in hemodialysis patients, to compare this with the normal population and to show the microorganisms’ antibiotic susceptibilities.

Materials and Methods: Patients receiving hemodialysis therapy for at least 3 years were included in the study. A control group (n=62) was established consisting of patients with no immune-suppressive condition and presenting to hospital with non-ear symptoms. Swab specimens were taken from all subjects’ external ear canals and nasal cavities. Results of the cultures were recorded and antimicrobial susceptibility test was performed.

Results: The most commonly isolated micro-organisms in the study group were MRCoNS (41%), followed by MSCoNS (15.5%) and diphtheroids (9.8%). The micro-organism most commonly isolated from the nasal cavity in the study group was CoNS (52.7%), of which MRCoNS constituted 69.2%.

Conclusion: We think that infections that play a major role in mortality and morbidity in hemodialysis patients may originate from the external ear canal as much as the nasal cavity, for this reason it is important for micro-organisms colonizing these regions to be eliminated with appropriate treatment on the basis of antibiotic susceptibility tests. 

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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Research Articles
Authors

Orcid: 0000-0001-6048-034X
Author: Korhan Kılıç (Primary Author)
Institution: Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum
Country: Turkey


Orcid: 0000-0002-4533-0308
Author: Eylül Derman
Institution: Atatürk University Faculty of Medicine, Department of Medical Microbiology, Erzurum
Country: Turkey


Orcid: 0000-0001-9588-1725
Author: Muhammed Sedat Sakat
Institution: Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum
Country: Turkey


Orcid: 0000-0002-9716-9579
Author: Mustafa Sıtkı Gözeler
Institution: Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum
Country: Turkey


Orcid: 0000-0003-1478-7441
Author: Hakan Uslu
Institution: Atatürk University Faculty of Medicine, Department of Medical Microbiology, Erzurum
Country: Turkey


Orcid: 0000-0001-9109-2681
Author: Furkan Şengöz
Institution: Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum
Country: Turkey


Dates

Publication Date: June 28, 2019

Bibtex @research article { etd458846, journal = {Ege Tıp Dergisi}, issn = {1016-9113}, eissn = {2147-6500}, address = {Ege University}, year = {2019}, volume = {58}, pages = {126 - 130}, doi = {10.19161/etd.458846}, title = {Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients}, key = {cite}, author = {Kılıç, Korhan and Derman, Eylül and Sakat, Muhammed Sedat and Gözeler, Mustafa Sıtkı and Uslu, Hakan and Şengöz, Furkan} }
APA Kılıç, K , Derman, E , Sakat, M , Gözeler, M , Uslu, H , Şengöz, F . (2019). Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients. Ege Tıp Dergisi, 58 (2), 126-130. DOI: 10.19161/etd.458846
MLA Kılıç, K , Derman, E , Sakat, M , Gözeler, M , Uslu, H , Şengöz, F . "Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients". Ege Tıp Dergisi 58 (2019): 126-130 <http://egetipdergisi.com.tr/issue/44438/458846>
Chicago Kılıç, K , Derman, E , Sakat, M , Gözeler, M , Uslu, H , Şengöz, F . "Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients". Ege Tıp Dergisi 58 (2019): 126-130
RIS TY - JOUR T1 - Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients AU - Korhan Kılıç , Eylül Derman , Muhammed Sedat Sakat , Mustafa Sıtkı Gözeler , Hakan Uslu , Furkan Şengöz Y1 - 2019 PY - 2019 N1 - doi: 10.19161/etd.458846 DO - 10.19161/etd.458846 T2 - Ege Tıp Dergisi JF - Journal JO - JOR SP - 126 EP - 130 VL - 58 IS - 2 SN - 1016-9113-2147-6500 M3 - doi: 10.19161/etd.458846 UR - https://doi.org/10.19161/etd.458846 Y2 - 2018 ER -
EndNote %0 Ege Journal of Medicine Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients %A Korhan Kılıç , Eylül Derman , Muhammed Sedat Sakat , Mustafa Sıtkı Gözeler , Hakan Uslu , Furkan Şengöz %T Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients %D 2019 %J Ege Tıp Dergisi %P 1016-9113-2147-6500 %V 58 %N 2 %R doi: 10.19161/etd.458846 %U 10.19161/etd.458846
ISNAD Kılıç, Korhan , Derman, Eylül , Sakat, Muhammed Sedat , Gözeler, Mustafa Sıtkı , Uslu, Hakan , Şengöz, Furkan . "Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients". Ege Tıp Dergisi 58 / 2 (June 2019): 126-130. https://doi.org/10.19161/etd.458846
AMA Kılıç K , Derman E , Sakat M , Gözeler M , Uslu H , Şengöz F . Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients. Ege Tıp Dergisi. 2019; 58(2): 126-130.
Vancouver Kılıç K , Derman E , Sakat M , Gözeler M , Uslu H , Şengöz F . Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients. Ege Tıp Dergisi. 2019; 58(2): 130-126.