Öz
Restless Legs Syndrome (RLS) primarily affects the legs, but atypical variants involving other body parts have been described. We present a 42-year-old patient presented with 10-year history of urinary urgency along with pain, numbness, and itchiness in the right hand and foot, which worsened and started affecting the left side over the past six months. The symptoms occurred predominantly at night, improved with urination and movement, and affected daily activities. Symptoms completely resolved with pramipexole treatment. The diagnostic criteria for RLS acknowledge atypical variants involving various body parts. Reported cases include genital, bladder, abdominal, bowel, head, oral, and phantom limb variants. Clinicians should consider therapeutic testing, such as with low-dose dopamine agonists, when there is a high clinical suspicion.
Anahtar Kelimeler
Kaynakça
- Allen RP, Picchietti DL, Garcia-Borreguero D, et al. Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria – history, rationale, description, and significance. Sleep Med. 2014;15(8):860-873. doi:10.1016/j.sleep.2014.03.025
- Turrini A, Raggi A, Calandra-Buonaura G, Martinelli P, Ferri R, Provini F. Not only limbs in atypical restless legs syndrome. Sleep Med Rev. 2018;38:50-55. doi:10.1016/j.smrv.2017.03.007
- Prakash S, Prakash A. Dopa responsive headache: Restless head syndrome or a cephalic variant of restless legs syndrome? J Fam Med Prim Care. 2020;9(8):4431. doi:10.4103/jfmpc.jfmpc_640_20
- Prakash S, Ahuja S, Rathod C. Dopa responsive burning mouth syndrome: Restless mouth syndrome or oral variant of restless legs syndrome? J Neurol Sci. 2012;320(1-2):156-160. doi:10.1016/j.jns.2012.07.007
- Perez-Diaz H, Iranzo A, Rye DB, Santamaria J. Restless abdomen: A phenotypic variant of restless legs syndrome. Neurology. 2011;77(13):1283-1286. doi:10.1212/WNL.0b013e318230207a
- Suzuki K, Miyamoto M, Uchiyama T, Miyamoto T, Matsubara T, Hirata K. Restless Bladder in an Elderly Woman: An Unusual Feature or a Variant of Restless Legs Syndrome? Intern Med Tokyo Jpn. 2016;55(18):2713-2716. doi:10.2169/internalmedicine.55.6815
- Sforza E, Hupin D, Roche F. Restless Genital Syndrome: Differential Diagnosis and Treatment With Pramipexole. J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med. 2017;13(9):1109-1110. doi:10.5664/jcsm.6736
- Nishida S, Hitsumoto A, Namba K, Usui A, Inoue Y. Persistence of secondary restless legs syndrome in a phantom limb caused by end-stage renal disease. Intern Med Tokyo Jpn. 2013;52(7):815-818. doi:10.2169/internalmedicine.52.9013
- Prakash S, Prakash A. Dopa responsive irritable bowel syndrome: restless bowel syndrome or a gastrointestinal variant of restless legs syndrome? BMJ Case Rep. 2021;14(3):e240686. doi:10.1136/bcr 2020-240686
- Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Agúndez JAG. Genetics of restless legs syndrome: An update. Sleep Medicine Reviews. 2018;39:108-121. doi:10.1016/j.smrv.2017.08.002
Öz
Huzursuz Bacaklar Sendromu (HBS) öncelikle bacakları etkiler, ancak diğer vücut bölgelerini içeren atipik varyantlar da tanımlanmıştır. Bu yazıda 10 yıldır olan, son altı aydır sol tarafını da etkilemeye başlayan, idrar hissi ile birlikte sağ el ve ayaklarda ağrı, uyuşma ve kaşıntı şikayeti olan 42 yaşında bir hasta sunulmuştur. Semptomlar ağırlıklı olarak geceleri ortaya çıkmakta, idrar yapma ve hareketle düzelmekte ve günlük aktiviteleri etkilemekteydi, pramipeksol tedavisi ile tamamen düzeldi. HBS için mevcut tanı kriterleri, çeşitli vücut bölgelerini içeren atipik varyantları kabul etmektedir. Bildirilen vakalar arasında genital, mesane, abdominal, bağırsak, baş, oral ve fantom uzuv varyantları bulunmaktadır. Klinisyenler, yüksek klinik şüphe halinde düşük doz dopamin agonistleri gibi terapötik testleri düşünmelidir.
Anahtar Kelimeler
Kaynakça
- Allen RP, Picchietti DL, Garcia-Borreguero D, et al. Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria – history, rationale, description, and significance. Sleep Med. 2014;15(8):860-873. doi:10.1016/j.sleep.2014.03.025
- Turrini A, Raggi A, Calandra-Buonaura G, Martinelli P, Ferri R, Provini F. Not only limbs in atypical restless legs syndrome. Sleep Med Rev. 2018;38:50-55. doi:10.1016/j.smrv.2017.03.007
- Prakash S, Prakash A. Dopa responsive headache: Restless head syndrome or a cephalic variant of restless legs syndrome? J Fam Med Prim Care. 2020;9(8):4431. doi:10.4103/jfmpc.jfmpc_640_20
- Prakash S, Ahuja S, Rathod C. Dopa responsive burning mouth syndrome: Restless mouth syndrome or oral variant of restless legs syndrome? J Neurol Sci. 2012;320(1-2):156-160. doi:10.1016/j.jns.2012.07.007
- Perez-Diaz H, Iranzo A, Rye DB, Santamaria J. Restless abdomen: A phenotypic variant of restless legs syndrome. Neurology. 2011;77(13):1283-1286. doi:10.1212/WNL.0b013e318230207a
- Suzuki K, Miyamoto M, Uchiyama T, Miyamoto T, Matsubara T, Hirata K. Restless Bladder in an Elderly Woman: An Unusual Feature or a Variant of Restless Legs Syndrome? Intern Med Tokyo Jpn. 2016;55(18):2713-2716. doi:10.2169/internalmedicine.55.6815
- Sforza E, Hupin D, Roche F. Restless Genital Syndrome: Differential Diagnosis and Treatment With Pramipexole. J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med. 2017;13(9):1109-1110. doi:10.5664/jcsm.6736
- Nishida S, Hitsumoto A, Namba K, Usui A, Inoue Y. Persistence of secondary restless legs syndrome in a phantom limb caused by end-stage renal disease. Intern Med Tokyo Jpn. 2013;52(7):815-818. doi:10.2169/internalmedicine.52.9013
- Prakash S, Prakash A. Dopa responsive irritable bowel syndrome: restless bowel syndrome or a gastrointestinal variant of restless legs syndrome? BMJ Case Rep. 2021;14(3):e240686. doi:10.1136/bcr 2020-240686
- Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Agúndez JAG. Genetics of restless legs syndrome: An update. Sleep Medicine Reviews. 2018;39:108-121. doi:10.1016/j.smrv.2017.08.002
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Nöroloji ve Nöromüsküler Hastalıklar |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 10 Haziran 2024 |
| Gönderilme Tarihi | 31 Ekim 2023 |
| Kabul Tarihi | 19 Aralık 2023 |
| Yayımlandığı Sayı | Yıl 2024 |