Sarcopenia prevalence and the quality of life in older adults: A study from Turkey’s east

Mehmet Efe; Zeliha Fulden Saraç; Sumru Savaş; Aslı Kılavuz; Selahattin Fehmi Akçiçek

doi:10.19161/etd.915678

Research Article

Yaşlı yetişkinlerde sarkopeni prevalansı ve yaşam kalitesi: Türkiye’nin doğusundan bir araştırma

Year 2021, Volume: 60 Suppl:1 (Geriatrics), 52 - 59, 19.04.2021

Mehmet Efe Zeliha Fulden Saraç Sumru Savaş Aslı Kılavuz Selahattin Fehmi Akçiçek

https://doi.org/10.19161/etd.915678

Cited By: 5

Abstract

Amaç: Sarkopeni; yaşam kalitesini düşüren, fonksiyonel bağımlılığı, mortaliteyi ve hastaneye yatış oranını artıran bir geriatrik sendromdur. Bu çalışma, Muş ilinde toplumda yaşayan 65 yaş ve üzeri yetişkinlerde sarkopeni prevalansını değerlendirmeyi ve yaşam kalitesi üzerindeki etkilerini incelemeyi amaçlamaktadır.

Gereç ve Yöntem: Bu çalışmada, Muş ilinde toplumda yaşayan toplam 371 katılımcıyla görüşüldü. Çalışmaya katılan yaşlı yetişkinlerin 186’sı Muş ilinin kırsal kesiminden, 185’i il merkezinde yaşamaktaydı. Veriler, katılımcıların evlerinde deneyimli araştırmacılar tarafından yüz yüze görüşme tekniğiyle toplanmıştır. Katılımcılarda sarkopeni varlığı, sosyo-demografik özellikler (yaş, cinsiyet, yaşadığı yer), kronik hastalık varlığı, polifarmasi, vücut kitle indeksi ve SF-36 yaşam kalitesi ölçeği ile yaşam kalitesi değerlendirilmiştir. Sarkopeniyi tanımlamak için yürüyüş hızı, el kavrama gücü ve baldır çevresine göre kas kütlesi belirlenmiştir.

Bulgular: Katılımcıların yaş ortalaması 72,3 ± 6,8 yıl (65-100) ve %46,1'i kadındı. Kırsal alanda yaşayan yaşlı yetişkinlerde sarkopeni prevalansı %11,8 iken, şehir merkezinde yaşayanlarda %21,6 idi (p = 0,012). Erkek katılımcılardan sarkopenik olanlar, sarkopenik olmayanlara göre daha yaşlı, daha zayıf, hipertansif ve daha düşük baldır çevresi, yürüme hızı ve kavrama gücüne sahipti (sırasıyla, p <0,0001, p <0,0001, p = 0,005, p <0,0001, p = 0,001, p <0,0001). Sarkopenik bireyler ile sarkopenik olmayan bireyler arasında fiziksel işlev, fiziksel rol zayıflığı ve duygusal rol zayıflığı açısından anlamlı farklılıklar saptandı (sırasıyla, p = 0,021, p = 0,006 ve p = 0,009).

Sonuç: Sarkopeni, özellikle şehir merkezinde yaşayan yaşlı yetişkinler arasında daha sık görülmüştür ve sarkopeni varlığının yaşam kalitesi üzerinde olumsuz etkileri vardır.

Keywords

Yaşlı , sarkopeni , yaşam kalitesi , prevalans.

References

Smith AP. The concept of well-being: relevance to nutrition research. British journal of nutrition 2005; 93 (1): 1-5.
de Jong N. Nutrition and senescence: Healthy aging for all in the new millennium? Nutrition 2000; 16 (7-8): 537-41.
Amine E, Baba N, Belhadj M, et al. Diet, nutrition and the prevention of chronic diseases. World Health Organization technical report series 2003. https://www.who.int/dietphysicalactivity/publications/trs916/en/gsfao_introduction.pdf (Accessed on
Heinrich M, Prieto JM. Diet and healthy ageing 2100: will we globalise local knowledge systems? Ageing Res Rev 2008; 7 (3): 249-74.
Burton LA, Sumukadas D. Optimal management of sarcopenia. Clin Interv Aging 2010; 5: 217-28.
Francesco L, Rosa L, Andrea R, et al. Sarcopenia as a risk factor for falls in elderly individuals: Results from the ilSIRENTE study. Clinical Nutrition 2012; 31 (5): 652-8.
Rosenberg IH. Summary comments. The American journal of clinical nutrition 1989; 50 (5): 1231-3.
Baumgartner RN, Koehler KM, Gallagher D, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 1998; 147 (8): 755-63.
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis. Age Ageing 2010; 39 (4): 412-23.
Pilar GC, Patricia SOP, José RB, Esther L, Fernando RA. Physical activity and quality of life in older adults in Spain. Medicina Clinica 2004; 123 (16): 606-61.
Hickey A, Barker M, McGee H, O’boyle C. Measuring health-related quality of life in older patient populations. Pharmacoeconomics 2005; 23 (10): 971-93.
Netuveli G, Blane D. Quality of life in older ages. Brit Med Bull 2008; 85 (1): 113-26.
O'boyle CA. Measuring the quality of later life. Philosophical Transactions of the Royal Society of London B: Biological Sciences 1997; 352 (1363): 1871-9.
EuroQol Group (1990-12-01). EuroQol--a new facility for the measurement of health-related quality of life. Health Policy (Amsterdam, Netherlands) 16 (3): 199–208.
Hunt SM, McEwan T: The development of a subjective health indicator. Soc of Health and Illness 1980; 2: 231–46.
Haywood K, Garratt A, Fitzpatrick R. Quality of life in older people: a structured review of generic selfassessed health instruments. Quality of life Research 2005; 14 (7): 1651-68.
Obesity, 2006. Guidance on the Prevention, Identification, Assessment and Management of Overweight and Obesity in Adults and Children. National Institute for Health and Clinical Excellence (NICE) Clinical Guideline 43. NICE, London.
Fielding RA, Vellas B, Evans WJ, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc 2011; 12 (4): 249-56.
Rolland Y, Lauwers-Cances V, Cournot M, et al. Sarcopenia, calf circumference, and physical function of elderly women: A cross-sectional study. J Am Geriatr Soc 2003; 51 (8): 1120-4.
Ware Jr JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Medical care 1992; 30 (6): 473-83.
Pınar R. Investigation of Quality of Life and Factors Affecting Quality of Life in Patients with Diabetes Mellitus. IU Institute of Health Sciences, PhD Thesis, Istanbul. 1995.
Morley JE. Sarcopenia: Diagnosis and treatment. J Nutr Health A. 2008; 12(7): 452-6.
Beaudart C, Reginster J-Y, Slomian J, et al. Estimation of sarcopenia prevalence using various assessment tools. Exp Gerontol 2015; 61: 31-7.
Pagotto V, Silveira EA. Applicability and agreement of different diagnostic criteria for sarcopenia estimation in the elderly. Arch Gerontol Geriat 2014; 59 (2): 288-94.
Yamada M, Nishiguchi S, Fukutani N, et al. Prevalence of sarcopenia in community-dwelling Japanese older adults. J Am Med Dir Assoc 2013; 14 (12): 911-5.
Arango-Lopera V, Arroyo P, Gutiérrez-Robledo L, Pérez-Zepeda M. Prevalence of sarcopenia in Mexico City, Eur Geriatr Med 2012; 3 (3): 157-60.
Iannuzzi-Sucich M, Prestwood KM, Kenny AM. Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2002; 57 (12): 772-7.
Martinez BP, Batista AKMS, Gomes IB, Olivieri FM, Camelier FWR, Camelier AA. Frequency of sarcopenia and associated factors among hospitalized elderly patients. Bmc Musculoskel Dis 2015; 16 (1): 108.
Mazocco L, Gonzalez MC, Barbosa-Silva TG, Chagas P. Sarcopenia in Brazilian rural and urban elderly women: Is there any difference? Nutrition 2019; 58: 120-4.
Pongchaiyakul C, Limpawattana P, Kotruchin P, Rajatanavin R. Prevalence of sarcopenia and associated factors among Thai population. J Bone Miner Metab 2013; 31 (3): 346-50.
Gao L, Jiang J, Yang M, Hao Q, Luo L, Dong B. Prevalence of Sarcopenia and Associated Factors in Chinese Community-Dwelling Elderly: Comparison Between Rural and Urban Areas. J Am Med Dir Assoc 2015; 16 (11): 1003.e1-6.
Cruz-Jentoft AJ. Sarcopenia: A clinical review. Rev Clin Gerontol 2013; 23: 267-74
Yoshida D, Suzuki T, Shimada H, et al. Using two different algorithms to determine the prevalence of sarcopenia. Geriatr Gerontol Int 2014; 14: 46-51.
Nasimi N, Dabbaghmanesh MH, Sohrabi Z. Nutritional status and body fat mass: Determinants of sarcopenia in community-dwelling older adults. Exp Gerontol 2019; 122: 67-73.
Tramontano A, Veronese N, Sergi G, et al. Prevalence of sarcopenia and associated factors in the healthy older adults of the Peruvian Andes. Arch Gerontol Geriatr 2017; 68: 49-54.
Senior HE, Henwood TR, Beller EM, Mitchell GK, Keogh JW. Prevalence and risk factors of sarcopenia among adults living in nursing homes. Maturitas 2015; 82 (4): 418-23.
Han P, Kang L, Guo Q, et al. Prevalence and Factors Associated With Sarcopenia in Suburb-dwelling Older Chinese Using the Asian Working Group for Sarcopenia Definition. J Gerontol A Biol Sci Med Sci 2016; 71 (4): 529-35.
Beaudart C, Reginster J-Y, Petermans J, et al. Quality of life and physical components linked to sarcopenia: the SarcoPhAge study. Exp Gerontol 2015; 69: 103-10.
Sayer AA, Syddall HE, Martin HJ, Dennison EM, Roberts HC, Cooper C. Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort Study. Age Ageing 2006; 35 (4): 409-15.
Go SW, Cha YH, Lee JA, Park HS. Association between sarcopenia, bone density, and health-related quality of life in Korean men. Korean J Fam Med 2013; 34 (4): 281-8.
Patel HP, Syddall HE, Jameson K, et al. Prevalence of Sarcopenia in Community-Dwelling Older People in the UK Using the European Working Group on Sarcopenia in Older People (EWGSOP) Definition: Findings from the Hertfordshire Cohort Study (HCS). Age and Ageing 2013; 42 (3): 378–84.
Kull M, Kallikorm R, Lember M. Impact of a New Sarco-Osteopenia Definition on Health-RelatedQuality of Life in a Population-Based Cohort in Northern Europe. Journal of Clinical Densitometry 2012; 15 (1): 32–8.
Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 2019; 48 (1): 16-31.
Bahat G, Saka B, Tufan F, et al. Prevalence of sarcopenia and its association with functional and nutritional status among male residents in a nursing home in Turkey. Aging Male 2010; 13 (3): 211-4.
Choi KM. Sarcopenia and sarcopenic obesity. Korean J Intern Med 2016; 31: 1054-60.
Barazzoni R, Bischoff S, Boirie Y, et al. Sarcopenic obesity: Time to meet the challenge. Obes Facts 2018; 11: 294-305.
Beaudart C, Biver E, Reginster JY, et al. Validation of the SarQoL®, a specific health-related quality of life questionnaire for Sarcopenia. Journal of Cachexia, Sarcopenia and Muscle, 2017: 8 (2), 238-44

Sarcopenia prevalence and the quality of life in older adults: A study from Turkey’s east

Year 2021, Volume: 60 Suppl:1 (Geriatrics), 52 - 59, 19.04.2021

Mehmet Efe Zeliha Fulden Saraç Sumru Savaş Aslı Kılavuz Selahattin Fehmi Akçiçek

https://doi.org/10.19161/etd.915678

Cited By: 5

Abstract

Aim: Sarcopenia as a geriatric syndrome decreases quality of life and increases functional dependency, hospitalization and mortality. The aim of this study is to investigate the prevalence of sarcopenia among community-dwelling people aged 65 years and older in Muş province and to examine its effects on quality of life.

Materials and Methods: In this study we have interviewed 371 community-dwelling older adults. A total of 186 older adults from the rural area and 185 older adults from Muş city center were enrolled in the study. Data was collected through face-to-face interviews conducted in the participants’ homes by trained researchers. The presence of sarcopenia, socio-demographic characteristics (place of residence, gender, age), presence of chronic diseases, polypharmacy, body mass index, and quality of life with Short Form-36 were determined. Muscle mass, handgrip strength and gait speed were determined for defining sarcopenia.

Results: The mean age of participants was 72.3 ± 6.8 years (65-100) and 46.1% of them were females. The prevalence of sarcopenia was 11.8% among older people residing in the rural area whereas the prevalence was 21.6% among older individuals living in the city center (p = 0.012).
Sarcopenic patients were older, more underweight, hypertensive, and had lower calf circumference, gait speed, and grip strength in males than non-sarcopenic patients (p <0.0001, p <0.0001, p = 0.005, p <0.0001, p = 0.001, p <0.0001, respectively). There were important distinction between sarcopenic individuals and non-sarcopenic individuals in terms of physical function, physical role weakness and emotional role weakness (p = 0.021, p = 0.006 and p = 0.009, respectively).

Conclusion: Sarcopenia is very common among older adults, especially in the city center, and the presence of sarcopenia has detrimental effects on the quality of life.

Keywords

Aged , sarcopenia , quality of life , prevalence

References

Smith AP. The concept of well-being: relevance to nutrition research. British journal of nutrition 2005; 93 (1): 1-5.
de Jong N. Nutrition and senescence: Healthy aging for all in the new millennium? Nutrition 2000; 16 (7-8): 537-41.
Amine E, Baba N, Belhadj M, et al. Diet, nutrition and the prevention of chronic diseases. World Health Organization technical report series 2003. https://www.who.int/dietphysicalactivity/publications/trs916/en/gsfao_introduction.pdf (Accessed on
Heinrich M, Prieto JM. Diet and healthy ageing 2100: will we globalise local knowledge systems? Ageing Res Rev 2008; 7 (3): 249-74.
Burton LA, Sumukadas D. Optimal management of sarcopenia. Clin Interv Aging 2010; 5: 217-28.
Francesco L, Rosa L, Andrea R, et al. Sarcopenia as a risk factor for falls in elderly individuals: Results from the ilSIRENTE study. Clinical Nutrition 2012; 31 (5): 652-8.
Rosenberg IH. Summary comments. The American journal of clinical nutrition 1989; 50 (5): 1231-3.
Baumgartner RN, Koehler KM, Gallagher D, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 1998; 147 (8): 755-63.
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis. Age Ageing 2010; 39 (4): 412-23.
Pilar GC, Patricia SOP, José RB, Esther L, Fernando RA. Physical activity and quality of life in older adults in Spain. Medicina Clinica 2004; 123 (16): 606-61.
Hickey A, Barker M, McGee H, O’boyle C. Measuring health-related quality of life in older patient populations. Pharmacoeconomics 2005; 23 (10): 971-93.
Netuveli G, Blane D. Quality of life in older ages. Brit Med Bull 2008; 85 (1): 113-26.
O'boyle CA. Measuring the quality of later life. Philosophical Transactions of the Royal Society of London B: Biological Sciences 1997; 352 (1363): 1871-9.
EuroQol Group (1990-12-01). EuroQol--a new facility for the measurement of health-related quality of life. Health Policy (Amsterdam, Netherlands) 16 (3): 199–208.
Hunt SM, McEwan T: The development of a subjective health indicator. Soc of Health and Illness 1980; 2: 231–46.
Haywood K, Garratt A, Fitzpatrick R. Quality of life in older people: a structured review of generic selfassessed health instruments. Quality of life Research 2005; 14 (7): 1651-68.
Obesity, 2006. Guidance on the Prevention, Identification, Assessment and Management of Overweight and Obesity in Adults and Children. National Institute for Health and Clinical Excellence (NICE) Clinical Guideline 43. NICE, London.
Fielding RA, Vellas B, Evans WJ, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc 2011; 12 (4): 249-56.
Rolland Y, Lauwers-Cances V, Cournot M, et al. Sarcopenia, calf circumference, and physical function of elderly women: A cross-sectional study. J Am Geriatr Soc 2003; 51 (8): 1120-4.
Ware Jr JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Medical care 1992; 30 (6): 473-83.
Pınar R. Investigation of Quality of Life and Factors Affecting Quality of Life in Patients with Diabetes Mellitus. IU Institute of Health Sciences, PhD Thesis, Istanbul. 1995.
Morley JE. Sarcopenia: Diagnosis and treatment. J Nutr Health A. 2008; 12(7): 452-6.
Beaudart C, Reginster J-Y, Slomian J, et al. Estimation of sarcopenia prevalence using various assessment tools. Exp Gerontol 2015; 61: 31-7.
Pagotto V, Silveira EA. Applicability and agreement of different diagnostic criteria for sarcopenia estimation in the elderly. Arch Gerontol Geriat 2014; 59 (2): 288-94.
Yamada M, Nishiguchi S, Fukutani N, et al. Prevalence of sarcopenia in community-dwelling Japanese older adults. J Am Med Dir Assoc 2013; 14 (12): 911-5.
Arango-Lopera V, Arroyo P, Gutiérrez-Robledo L, Pérez-Zepeda M. Prevalence of sarcopenia in Mexico City, Eur Geriatr Med 2012; 3 (3): 157-60.
Iannuzzi-Sucich M, Prestwood KM, Kenny AM. Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2002; 57 (12): 772-7.
Martinez BP, Batista AKMS, Gomes IB, Olivieri FM, Camelier FWR, Camelier AA. Frequency of sarcopenia and associated factors among hospitalized elderly patients. Bmc Musculoskel Dis 2015; 16 (1): 108.
Mazocco L, Gonzalez MC, Barbosa-Silva TG, Chagas P. Sarcopenia in Brazilian rural and urban elderly women: Is there any difference? Nutrition 2019; 58: 120-4.
Pongchaiyakul C, Limpawattana P, Kotruchin P, Rajatanavin R. Prevalence of sarcopenia and associated factors among Thai population. J Bone Miner Metab 2013; 31 (3): 346-50.
Gao L, Jiang J, Yang M, Hao Q, Luo L, Dong B. Prevalence of Sarcopenia and Associated Factors in Chinese Community-Dwelling Elderly: Comparison Between Rural and Urban Areas. J Am Med Dir Assoc 2015; 16 (11): 1003.e1-6.
Cruz-Jentoft AJ. Sarcopenia: A clinical review. Rev Clin Gerontol 2013; 23: 267-74
Yoshida D, Suzuki T, Shimada H, et al. Using two different algorithms to determine the prevalence of sarcopenia. Geriatr Gerontol Int 2014; 14: 46-51.
Nasimi N, Dabbaghmanesh MH, Sohrabi Z. Nutritional status and body fat mass: Determinants of sarcopenia in community-dwelling older adults. Exp Gerontol 2019; 122: 67-73.
Tramontano A, Veronese N, Sergi G, et al. Prevalence of sarcopenia and associated factors in the healthy older adults of the Peruvian Andes. Arch Gerontol Geriatr 2017; 68: 49-54.
Senior HE, Henwood TR, Beller EM, Mitchell GK, Keogh JW. Prevalence and risk factors of sarcopenia among adults living in nursing homes. Maturitas 2015; 82 (4): 418-23.
Han P, Kang L, Guo Q, et al. Prevalence and Factors Associated With Sarcopenia in Suburb-dwelling Older Chinese Using the Asian Working Group for Sarcopenia Definition. J Gerontol A Biol Sci Med Sci 2016; 71 (4): 529-35.
Beaudart C, Reginster J-Y, Petermans J, et al. Quality of life and physical components linked to sarcopenia: the SarcoPhAge study. Exp Gerontol 2015; 69: 103-10.
Sayer AA, Syddall HE, Martin HJ, Dennison EM, Roberts HC, Cooper C. Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort Study. Age Ageing 2006; 35 (4): 409-15.
Go SW, Cha YH, Lee JA, Park HS. Association between sarcopenia, bone density, and health-related quality of life in Korean men. Korean J Fam Med 2013; 34 (4): 281-8.
Patel HP, Syddall HE, Jameson K, et al. Prevalence of Sarcopenia in Community-Dwelling Older People in the UK Using the European Working Group on Sarcopenia in Older People (EWGSOP) Definition: Findings from the Hertfordshire Cohort Study (HCS). Age and Ageing 2013; 42 (3): 378–84.
Kull M, Kallikorm R, Lember M. Impact of a New Sarco-Osteopenia Definition on Health-RelatedQuality of Life in a Population-Based Cohort in Northern Europe. Journal of Clinical Densitometry 2012; 15 (1): 32–8.
Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 2019; 48 (1): 16-31.
Bahat G, Saka B, Tufan F, et al. Prevalence of sarcopenia and its association with functional and nutritional status among male residents in a nursing home in Turkey. Aging Male 2010; 13 (3): 211-4.
Choi KM. Sarcopenia and sarcopenic obesity. Korean J Intern Med 2016; 31: 1054-60.
Barazzoni R, Bischoff S, Boirie Y, et al. Sarcopenic obesity: Time to meet the challenge. Obes Facts 2018; 11: 294-305.
Beaudart C, Biver E, Reginster JY, et al. Validation of the SarQoL®, a specific health-related quality of life questionnaire for Sarcopenia. Journal of Cachexia, Sarcopenia and Muscle, 2017: 8 (2), 238-44

There are 47 citations in total.

Details

Primary Language	English
Subjects	Health Care Administration
Journal Section	Research Articles
Authors	Mehmet Efe 0000-0002-8337-2584 Zeliha Fulden Saraç 0000-0001-9281-2492 Sumru Savaş 0000-0003-4836-3786 Aslı Kılavuz 0000-0002-0474-9911 Selahattin Fehmi Akçiçek 0000-0003-2583-4709
Publication Date	April 19, 2021
Submission Date	January 18, 2021
Published in Issue	Year 2021 Volume: 60 Suppl:1 (Geriatrics)

Cite

Vancouver	Efe M, Saraç ZF, Savaş S, Kılavuz A, Akçiçek SF. Sarcopenia prevalence and the quality of life in older adults: A study from Turkey’s east. EJM. 2021:52-9.