Rejeneratif tıpta model organizma; Aksolotl (Ambystoma Mexicanum)

Burak Çakar; Canberk Tomruk; Servet Çelik; Yiğit Uyanıkgil

doi:10.19161/etd.1086385

TR EN

Model organism in regenerative medicine; Axolotl (Ambystoma Mexicanum)

Öz

Sinir sistemi, ektremiteler, göz ve kalp gibi organlar olmak üzere hasarlanan ve yitirilen yapılarını skar oluşturmaksızın olağanüstü derecede yenileme kapasitesine sahip olan aksolotl; hem gelişimsel biyolojide hem de rejeneratif tıp ve kök hücre biyolojisi alanında çalışan bilim insanlarının dikkatini çekerek oldukça önemli bir model organizma haline gelmiştir. Amfibi ve tetrapod olan aksolotl, nispeten çalışılması zor olan Afrika pençeli kurbağası (Xenopus laevis) veya zebra balığı (Danio rerio) gibi diğer organizmalara göre bakımı ve üremesinin kolaylığı sebebiyle daha çok tercih edilen bir modeldir. Bu derlemenin temel amaçları; aksolotlın tanımı ve kökeninden başlayarak, taksonomisi, anatomisi, üremesi, beslenmesi, yaşam alanını, bilimsel çalışmalara model organizma olarak nasıl katkı sağladığı gibi konulara değinerek son 20 yıldaki bilimsel verileri ve çalışma alanlarına örnekler vererek bu model organizma üzerinde çalışmak isteyen bilim insanlarına bakış açısı kazandırmaktır.

Anahtar Kelimeler

Supporting Institution

Yok

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Review

Authors

Burak Çakar
0000-0002-4334-9320
Türkiye

Canberk Tomruk
0000-0002-3810-3705
Türkiye

Servet Çelik ^*
0000-0002-1102-4417
Türkiye

Yiğit Uyanıkgil
0000-0002-4016-0522
Türkiye

Publication Date

March 15, 2022

Submission Date

September 26, 2021

Acceptance Date

November 8, 2021

Published in Issue

Year 1970 Volume: 61 Number: 1

DOI

https://doi.org/10.19161/etd.1086385

IZ

https://izlik.org/JA29BB74YC

Cite

RIS / Bibtex

Vancouver

1.Burak Çakar, Canberk Tomruk, Servet Çelik, Yiğit Uyanıkgil. Rejeneratif tıpta model organizma; Aksolotl (Ambystoma Mexicanum). EJM. 2022 Mar. 1;61(1):122-8. doi:10.19161/etd.1086385

Rejeneratif tıpta model organizma; Aksolotl (Ambystoma Mexicanum)

Model organism in regenerative medicine; Axolotl (Ambystoma Mexicanum)

Öz

Anahtar Kelimeler