Fuchs heterokromik iridosiklit hastalarında kornea biyomekaniği ve kornea değerlendirilmesi

Semir Yarımada; Cumali Değirmenci; Melis Palamar; Suzan Güven Yılmaz; Halil Ateş

doi:10.19161/etd.1127207

EN TR

Corneal biomechanics and cornea assessment in Fuchs heterochromic iridocyclitis patients

Abstract

Aim: To evaluate cornea and corneal biomechanical properties of patients with Fuchs heterochromic iridocylitis.

Materials and Methods: Fourteen FHI positive eyes (Group 1) and the contralateral healthy eyes (Group 2) were included. All patients underwent a detailed ophthalmic examination was performed. Also, Ocular Response Analyzer was used to detect corneal biomechanical properties, and specular microscopic evaluation for corneal endothelial cells count was performed.

Results: The mean best corrected visual acuity and intraocular pressure were statistically similar. (p values were 0.077 and 0.557, respectively). Corneal biomechanical properties including corneal hysteresis, corneal resistance factor, IOPcc and IOPg were not statistically significant. (p values were 0.521, 0.817, 0.980 and 0.980, respectively). Mean central corneal thickness in Group 1 and 2 were 555.57±42.95 (467-626), 556.5±37.04 (480-623) micrometer, respectively. The difference was not statistically significant (p=0.959). Mean corneal endothelial cell density of Group 1 and Group 2 were 2313±420.22 (1271-2717) and 2404.42±326.75 (1566-2834) cells/mm2, respectively. The difference was not statistically significant (p=0.626).

Conclusion: Conflicting with the literature, no differences were detected in corneal biomechanical properties, central corneal thickness and corneal endothelial cell density in Fuchs Heterochromic Iridocyclitis positive eyes. However, more studies with increasing number of patients are still needed.

Keywords

Fuchs heterokromik iridosiklit hastalarında kornea biyomekaniği ve kornea değerlendirilmesi

Öz

Amaç: Bu çalışmanın amacı Fuchs heterokromik iridosiklit (FHİ) tanılı gözler ile sağlıklı diğer gözlerin kornealarının ve kornea biyomekanik özelliklerinin karşılaştırılmasıdır.

Gereç ve Yöntem: Fuchs heterokromik iridosiklit tanılı 14 göz (Grup 1) ve sağlıklı diğer gözler (Grup 2) çalışmaya dâhil edildi. Tüm hastalara detaylı bir oftalmolojik bakıyı takiben Ocular Response Analyzer korneal biyomekanik özellikler ve speküler mikroskobi ile santral korneal kalınlık (SKK), korneal endotelyal hücre dansitesi (KEHD) değerlendirildi.

Bulgular: En iyi düzeltilmiş görme keskinliği ve intraoküler basınç istatistiksel olarak benzerdi (p değerleri sırasıyla 0,077 ve 0,557). Korneal biyomekanik parametreleri olan korneal histerezis, korneal resiztans faktör, IOPcc ve IOPg değerleri her iki grupta istatistiksel olarak benzerdi (p değerleri sırasıyla; 0,521, 0,817, 0,980 ve 0,980 idi). Ortalama santral korneal kalınlık Grup 1’de 555,57±42,95 (467-626) mikron ve Grup 2’de 556,5±37,04 (480-623) mikron olarak saptandı (p=0,959). Ortalama korneal endotel hücre dansitesi Grup 1’de 2313±420,22 (1271-2717) ve Grup 2’de 2404,42±326,75 (1566-2834) hücre/mm2 saptandı (p=0,626).

Sonuç: Sağlıklı gözler ile Fuchs Heterokromik İridosiklit tanılı gözler karşılaştırıldığında kornea biyomekanik parametreleri ve korneal endotel hücre dansitesi arasında anlamlı fark saptanmamıştır. Bu sonuçlar literatürdeki birçok çalışma ile çelişmekte olup daha geniş vaka serileri ile yeni çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

References

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Semir Yarımada
0000-0001-8660-1939
Türkiye

Cumali Değirmenci ^*
0000-0002-8268-536X
Türkiye

Melis Palamar
0000-0002-2494-0131
Türkiye

Suzan Güven Yılmaz
0000-0001-8720-007X
Türkiye

Halil Ateş
0000-0003-1799-8666
Türkiye

Publication Date

June 13, 2022

Submission Date

September 19, 2021

Acceptance Date

December 27, 2021

Published in Issue

Year 2022 Volume: 61 Number: 2

DOI

https://doi.org/10.19161/etd.1127207

IZ

https://izlik.org/JA96JE66TU

Cite

RIS / Bibtex

Vancouver

1.Semir Yarımada, Cumali Değirmenci, Melis Palamar, Suzan Güven Yılmaz, Halil Ateş. Fuchs heterokromik iridosiklit hastalarında kornea biyomekaniği ve kornea değerlendirilmesi. EJM. 2022 Jun. 1;61(2):244-8. doi:10.19161/etd.1127207