Correlation of the neuropathic pain and electrodiagnostic tests in earthquake-related peripheral nerve injuries

Metin Balduz; Halit Fidancı

doi:10.19161/etd.1585024

TR EN

Depremle ilişkili periferik sinir yaralanmalarında nöropatik ağrı ile elektrodiyagnostik testlerin korelasyonu

Öz

Amaç: Depremle ilişkili enkaz altında kalmaya bağlı gelişen periferik sinir yaralanmaları nöropatik ağrıya yol açabilir. Bu çalışma, enkaz altında kalma sonucu periferik sinir hasarı olan hastalarda nöropatik ağrı ile elektrodiyagnostik test bulguları arasındaki ilişkiyi araştırmaktadır. Gereç ve Yöntem: Bu retrospektif çalışma, Şubat 2023'te Kahramanmaraş merkezli depremler sırasında enkaz altında kalma sonucu oluşan periferik sinir hasarı gelişen hastaları içermektedir. Bileşik sinir aksiyon potansiyelleri (CNAP) ve bileşik kas aksiyon potansiyellerindeki (CMAP) anormallikler hafif, orta veya şiddetli olarak kategorize edilmiştir. Bulgular: Bu çalışmaya 62 (34 kadın, 28 erkek) hasta dahil edilmiştir. Ortalama (min-maks) hastalık süresi, enkaz altında kalma süresi ve DN4 skorları sırasıyla 59,4 ± 37,1 (21-180) gün, 22,6 ± 29,7 (0,5-130) saat ve 4,9 ± 1,7 (1-9) olarak bulunmuştur. Şiddetli CNAP/CMAP anormalliklerinin sayısı ile DN4 skorları arasında pozitif bir korelasyon gözlenmiştir (p=0,024, r=0,287 / p=0,003, r=0,371). En az bir veya en az iki sinirde şiddetli CMAP anormallikleri olan hastalar, anormallik bulunmayan hastalara göre daha yüksek DN4 skorlarına sahipti (p=0,039 / p=0,009). Sonuç: Bu çalışma, enkaz altında kalmaya bağlı periferik sinir hasarı olan hastalarda nöropatik ağrı ile şiddetli CNAP/CMAP anormallikleri arasındaki ilişkiye dikkat çekmektedir.

Anahtar Kelimeler

Correlation of the neuropathic pain and electrodiagnostic tests in earthquake-related peripheral nerve injuries

Abstract

Aim: Peripheral nerve injury resulting from being buried under earthquake-related debris can lead to neuropathic pain. This study investigates the relationship between neuropathic pain and electrodiagnostic test findings in patients with peripheral nerve lesions caused by entrapment under debris. Materials and Methods: This retrospective study included patients who developed peripheral nerve lesions due to entrapment under debris during the Kahramanmaraş-centered earthquakes in February 2023. Abnormalities in compound nerve action potentials (CNAPs) and compound muscle action potentials (CMAPs) were categorized as mild, moderate, or severe. Results: 62 (34 female, 28 male) patients were included in this study. The mean (min-max) disease duration, time under debris, and Douleur Neuropathique 4 Questions (DN4) scores were 59.4 ± 37.1 (21-180) days, 22.6 ± 29.7 (0.5-130) hours, and 4.9 ± 1.7 (1-9), respectively. A positive correlation was observed between the number of severe CNAP/CMAP abnormalities and DN4 scores (p=0.024, r=0.287/ p=0.003, r=0.371). Patients with severe CMAP abnormalities in at least one or at least two nerves had higher DN4 scores compared to those without (p=0.039/p=0.009). Conclusion: This study highlights a relationship between neuropathic pain and severe CNAP/CMAP abnormalities in patients with peripheral nerve lesions due to entrapment under debris.

Keywords

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Details

Primary Language

English

Subjects

Neurology and Neuromuscular Diseases

Journal Section

Research Article

Authors

Metin Balduz ^*
0000-0002-1542-8005
Türkiye

Halit Fidancı
0000-0001-6573-9090
Türkiye

Publication Date

June 10, 2025

Submission Date

November 13, 2024

Acceptance Date

January 16, 2025

Published in Issue

Year 2025 Volume: 64 Number: 2

DOI

https://doi.org/10.19161/etd.1585024

IZ

https://izlik.org/JA99PM82TT

Cite

RIS / Bibtex

Vancouver

1.Metin Balduz, Halit Fidancı. Correlation of the neuropathic pain and electrodiagnostic tests in earthquake-related peripheral nerve injuries. EJM. 2025 Jun. 1;64(2):201-8. doi:10.19161/etd.1585024