Case Report

Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history

Volume: 65 Number: 3 September 3, 2026
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Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history

Abstract

Erythema migrans, the hallmark rash of early Lyme borreliosis, is caused by Borrelia burgdorferi sensu lato and transmitted through the bite of infected Ixodes species ticks. We report a case of a 25-year-old woman with no history of tick bite who presented with pruritic annular erythematous plaques on the lower extremities following recent travel to a Lyme-endemic region. Serological testing revealed elevated Borrelia burgdorferi IgM antibodies, and Western blot analysis corroborated the diagnosis of early disseminated Lyme disease. This case highlights the importance of suspecting Lyme borreliosis in patients presenting with characteristic skin lesions and relevant travel history, even in the absence of a recalled tick bite. Given the risk of progression to serious late-stage complications, including arthritis, neuropathy, and carditis, prompt clinical recognition and early initiation of appropriate antimicrobial therapy are essential to minimize morbidity.

Keywords

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Ethical Statement

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Thanks

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References

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Details

Primary Language

English

Subjects

Emergency Medicine, Dermatology

Journal Section

Case Report

Publication Date

September 3, 2026

Submission Date

January 12, 2026

Acceptance Date

May 18, 2026

Published in Issue

Year 2026 Volume: 65 Number: 3

APA
Haidara, Z., & Aslaner, M. A. (2026). Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history. Ege Tıp Dergisi, 65(3), 612-615. https://doi.org/10.19161/etd.1862178
AMA
1.Haidara Z, Aslaner MA. Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history. EJM. 2026;65(3):612-615. doi:10.19161/etd.1862178
Chicago
Haidara, Zeynab, and Mehmet Ali Aslaner. 2026. “Erythema Migrans in Lyme Disease: Diagnostic Challenge Without Tick Bite History”. Ege Tıp Dergisi 65 (3): 612-15. https://doi.org/10.19161/etd.1862178.
EndNote
Haidara Z, Aslaner MA (September 1, 2026) Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history. Ege Tıp Dergisi 65 3 612–615.
IEEE
[1]Z. Haidara and M. A. Aslaner, “Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history”, EJM, vol. 65, no. 3, pp. 612–615, Sept. 2026, doi: 10.19161/etd.1862178.
ISNAD
Haidara, Zeynab - Aslaner, Mehmet Ali. “Erythema Migrans in Lyme Disease: Diagnostic Challenge Without Tick Bite History”. Ege Tıp Dergisi 65/3 (September 1, 2026): 612-615. https://doi.org/10.19161/etd.1862178.
JAMA
1.Haidara Z, Aslaner MA. Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history. EJM. 2026;65:612–615.
MLA
Haidara, Zeynab, and Mehmet Ali Aslaner. “Erythema Migrans in Lyme Disease: Diagnostic Challenge Without Tick Bite History”. Ege Tıp Dergisi, vol. 65, no. 3, Sept. 2026, pp. 612-5, doi:10.19161/etd.1862178.
Vancouver
1.Zeynab Haidara, Mehmet Ali Aslaner. Erythema migrans in Lyme disease: Diagnostic challenge without tick bite history. EJM. 2026 Sep. 1;65(3):612-5. doi:10.19161/etd.1862178

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