The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions

Zeynep Tanrıverdi; Sıla Yılmaz Kalkan; Nurcan Akbulut; Yeşim Beckmann; Fazıl Gelal

doi:10.19161/etd.1867158

TR EN

Baziler arter morfolojisinin pontin infarkt gelişimi üzerine etkisi

Abstract

Amaç: Vertebrobaziler arteriyel sistemdeki varyasyonlar serebral hemodinamiği etkileyerek vasküler hastalıklara neden olabilir. İç kulak kanlanması da vertebrobaziler sistemden kaynaklandığı için izole vertigosu olan hastalar arka sistem infarktı geçirme riski taşımaktadır. Çalışmamız, izole vertigo şikayeti olan hastalar ile izole pontin infarkt geçiren hastalar arasında baziler arter morfolojisini karşılaştırmayı amaçlamaktadır. Gereç ve Yöntem: Eylül 2019 ile Ağustos 2023 tarihleri arasında akut izole pontin infarkt tanısı alan 80 hastanın ve izole vertigo nedeni ile tetkik edilen 59 hastanın verileri retrospektif olarak analiz edildi. Demografik özellikler, vasküler risk faktörleri, nörogörüntüleme bulguları ve etiyolojiler kaydedildi. Baziler arter konfigürasyonu, baziler arter uzunluğu, baziler arter bükülme mesafesi, vertebral arter dominansı ve bulber temas değerlendirildi. Bulgular: Hipertansiyon, diyabetes mellitus, hiperlipidemi, geçirilmiş arka sistem infarktı ve sigara kullanımı infarkt grubunda anlamlı derecede daha sıktı (p<0,05). Baziler arterde C‑şeklinde konfigürasyon her iki grupta da en yaygın tipti ve iskemi ile ilişkili değildi. Baziler arter uzunluğu ve bükülme mesafesi infarkt gelişimi ile anlamlı bir korelasyon göstermedi. Buna karşılık, vertebral arterin bulber teması infarkt grubunda belirgin ölçüde sıktı (p<0,001). Dominant vertebral arterin baziler arteri karşı tarafa doğru ittiği gözlendi. Sonuç: Pontin infarktların çoğu küçük damar hastalığıyla ilişkili görünmektedir. Bu hastalarda baziler artere ait morfolojik değişiklikler saptanabilse de benzer değişiklikler izole vertigo olgularında da yaygındır; bu durum baziler arter varyasyonlarının pontin infarktlara spesifik olmadığını göstermektedir. Baziler arter morfolojisine genetik, ırksal ve diğer etkenlerin katkılarını ve bunun klinik önemini netleştirmek için daha büyük, toplum temelli çalışmalara ihtiyaç vardır.

Keywords

Supporting Institution

destekleyen kurum yoktur

Ethical Statement

makalenin hazırlanma sürecinde bilimsel ve etik ilkelere uyulmuştur ve yaralanılan çalışmalar kaynakçada belirtilmiştir.

The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions

Abstract

Aim: Variations in the vertebrobasilar arterial system can influence cerebral hemodynamics and predispose to vascular disease. Because the inner ear is supplied by the vertebrobasilar circulation, patients with isolated vertigo may have increased posterior circulation stroke risk. This study compared basilar artery morphology between patients with isolated vertigo and those with pontine infarction. Materials and Methods: We retrospectively analyzed 80 patients admitted with acute isolated PI and 59 controls presenting with isolated vertigo between September 2019 and August 2023. Demographics, vascular risk factors, neuroimaging features, and etiologies were reviewed. BA configuration, basilar artery length, basilar artery bending distance, vertebral artery dominance, and bulbar contact were assessed. Results: Hypertension, diabetes mellitus, hyperlipidemia, prior posterior circulation stroke, and smoking were significantly more prevalent in the PI group (p<0.05). The C-shaped BA configuration was the most common in both groups and was not associated with PI. Neither BAL nor BABD correlated significantly with PI. In contrast, VA bulbar contact was markedly more frequent in the PI group (p<0.001). The dominant VA tended to displace the BA laterally toward the contralateral side. Conclusions: Most PIs appear related to small vessel disease. Although BA morphological alterations are detectable in PI, similar changes are also common in isolated vertigo, indicating that BA variants are not specific to infarction. Larger, population-based studies are needed to clarify the contributions of genetic, racial, and other factors to BA morphology and its clinical relevance.

Keywords

Supporting Institution

no funding organization

Ethical Statement

The article has been prepared in accordance with scientific and ethical principles, and the studies used are listed in the references section.

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Details

Primary Language

English

Subjects

Clinical Sciences (Other)

Journal Section

Research Article

Authors

Zeynep Tanrıverdi ^*
0000-0001-9490-5342
Türkiye

Sıla Yılmaz Kalkan
0000-0003-0874-1068
Türkiye

Nurcan Akbulut
0000-0002-6609-0016
Türkiye

Yeşim Beckmann
0000-0001-5158-8834
Türkiye

Fazıl Gelal
0000-0003-1263-0918
Türkiye

Publication Date

September 3, 2026

Submission Date

January 21, 2026

Acceptance Date

April 8, 2026

Published in Issue

Year 2026 Volume: 65 Number: 3

DOI

https://doi.org/10.19161/etd.1867158

IZ

https://izlik.org/JA72MT77PD

Cite

RIS / Bibtex

APA

Tanrıverdi, Z., Yılmaz Kalkan, S., Akbulut, N., Beckmann, Y., & Gelal, F. (2026). The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions. Ege Tıp Dergisi, 65(3), 394-402. https://doi.org/10.19161/etd.1867158

AMA

1.Tanrıverdi Z, Yılmaz Kalkan S, Akbulut N, Beckmann Y, Gelal F. The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions. EJM. 2026;65(3):394-402. doi:10.19161/etd.1867158

Chicago

Tanrıverdi, Zeynep, Sıla Yılmaz Kalkan, Nurcan Akbulut, Yeşim Beckmann, and Fazıl Gelal. 2026. “The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions”. Ege Tıp Dergisi 65 (3): 394-402. https://doi.org/10.19161/etd.1867158.

EndNote

Tanrıverdi Z, Yılmaz Kalkan S, Akbulut N, Beckmann Y, Gelal F (September 1, 2026) The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions. Ege Tıp Dergisi 65 3 394–402.

IEEE

[1]Z. Tanrıverdi, S. Yılmaz Kalkan, N. Akbulut, Y. Beckmann, and F. Gelal, “The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions”, EJM, vol. 65, no. 3, pp. 394–402, Sept. 2026, doi: 10.19161/etd.1867158.

ISNAD

Tanrıverdi, Zeynep - Yılmaz Kalkan, Sıla - Akbulut, Nurcan - Beckmann, Yeşim - Gelal, Fazıl. “The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions”. Ege Tıp Dergisi 65/3 (September 1, 2026): 394-402. https://doi.org/10.19161/etd.1867158.

JAMA

1.Tanrıverdi Z, Yılmaz Kalkan S, Akbulut N, Beckmann Y, Gelal F. The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions. EJM. 2026;65:394–402.

MLA

Tanrıverdi, Zeynep, et al. “The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions”. Ege Tıp Dergisi, vol. 65, no. 3, Sept. 2026, pp. 394-02, doi:10.19161/etd.1867158.

Vancouver

1.Zeynep Tanrıverdi, Sıla Yılmaz Kalkan, Nurcan Akbulut, Yeşim Beckmann, Fazıl Gelal. The Influence of Basilar Artery Morphology on the Development of Pontine Infarctions. EJM. 2026 Sep. 1;65(3):394-402. doi:10.19161/etd.1867158