From neonate to adolescent: A review of ovarian mass management in a single center

Asya Eylem Boztas; Ayşe Demet Payza; Süleyman Perçin; Arzu Şencan

doi:10.19161/etd.1935423

TR EN

Yenidoğandan adölesan döneme: Tek bir merkezin over kitle yönetiminin derlemesi

Abstract

Amaç: Pediatrik over ve adneksiyal kitleler benign ve malign patolojileri içeren geniş bir spektruma sahiptir ve yönetim stratejileri konservatif izlemden cerrahiye kadar değişmektedir. Bu çalışmada, üçüncü basamak bir merkezde yenidoğan dönemden adölesan döneme kadar pediatrik over ve adneksiyal kitlelerin klinik başvuru özellikleri, yönetim yaklaşımları, cerrahi sonuçları ve histopatolojik bulgularının değerlendirilmesi amaçlandı. Gereç ve Yöntem: 2018–2024 yılları arasında kliniğimizde adneksiyal kist/kitle nedeniyle takip ve tedavi edilen 0–18 yaş arası pediatrik hastaların demografik, laboratuvar, ultrasonografik, cerrahi ve histopatolojik verileri retrospektif olarak incelendi. Yenidoğan ve yenidoğan dışı hastalar arasında alt grup analizleri yapıldı. Bulgular: Toplam 1000 hastanın 786’sı çalışmaya dahil edildi. Ortalama yaş 11,99±5,28 yıl olup, 93 hasta (%11,8) yenidoğan dönemindeydi. Hastaların 634’ünde (%80,7) konservatif izlem tercih edilirken, 152 hastaya (%19,3) cerrahi tedavi uygulandı. Cerrahi uygulanan hastalarda en sık over koruyucu girişim kist eksizyonu olup 99 hastaya uygulandı. Otuz iki hastada ooforektomi, 21 hastada salpingo-ooforektomi yapıldı. Histopatolojik incelemede lezyonların büyük çoğunluğu benign (%98) olup yalnızca iki malign tümör saptandı. Cerrahi müdahale oranı yenidoğan ve yenidoğan dışı hastalar arasında anlamlı farklılık göstermedi (%14,0’a karşı %20,1; p=0,163). Ancak opere edilen olgularda over kaybı oranı yenidoğanlarda anlamlı olarak daha yüksekti (p=0,007). Sonuç: Pediatrik adneksiyal kitleler çoğunlukla benign olup hastaların büyük kısmı güvenle konservatif izlenebilir. Cerrahi gerektiğinde mümkün olduğunca over korunmalıdır. Yenidoğan hastalar, daha uzun izlem gereksinimi ve daha yüksek over kaybı oranları nedeniyle ayrı bir alt grup olarak değerlendirilmelidir.

Keywords

From neonate to adolescent: A review of ovarian mass management in a single center

Abstract

Aim: Pediatric ovarian and adnexal masses encompass a broad spectrum of benign and malignant pathologies, with management strategies ranging from observation to surgery. This study aimed to evaluate the clinical presentation, management approaches, surgical outcomes, and histopathological findings of pediatric ovarian and adnexal masses across the full age spectrum, from the neonatal period to adolescence, at a single tertiary center. Materials and Methods: A retrospective analysis was conducted on the demographic, laboratory, sonographic, surgical, and histopathological data of pediatric patients (0-18 years) who were followed up and treated for adnexal cysts/masses in our clinic between 2018 and 2024. Subgroup analyses were conducted between neonatal and non-neonatal patients. Results: A total of 786 of 1000 screened patients were included in the final analysis, with a mean age of 11.99 ± 5.28 years; 93 patients (11.8%) were in the neonatal period. Conservative management was the predominant strategy, used in 634 patients (80.7%), while 152 patients (19.3%) underwent surgery. Among operated patients, ovarian-sparing procedures were most common, with cyst excision performed in 99 patients. Oophorectomy was required in 32 patients, and salpingo-oophorectomy in 21 patients. Histopathological evaluation demonstrated predominantly benign lesions (98%), with only two malignant tumors identified. The rate of surgical intervention did not differ significantly between neonatal and non-neonatal patients (14.0% vs. 20.1%, p=0.163). However, neonatal patients had significantly higher ovarian loss rates among operated cases (p=0.007). Conclusions: Pediatric adnexal masses are predominantly benign and can be safely managed conservatively in most patients. When surgery is required, ovarian preservation should be prioritized whenever feasible. Neonatal patients represent a distinct subgroup with longer surveillance needs and higher rates of ovarian loss, supporting age-specific management strategies.

Keywords

References

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Details

Primary Language

English

Subjects

Clinical Sciences (Other)

Journal Section

Research Article

Authors

Asya Eylem Boztas ^*
0000-0002-5663-9394
Türkiye

Ayşe Demet Payza
0009-0002-9121-775X
Türkiye

Süleyman Perçin
0009-0004-7103-1493
Türkiye

Arzu Şencan
0000-0003-4499-7984
Türkiye

Publication Date

September 3, 2026

Submission Date

April 22, 2026

Acceptance Date

July 16, 2026

Published in Issue

Year 2026 Volume: 65 Number: 3

DOI

https://doi.org/10.19161/etd.1935423

IZ

https://izlik.org/JA23TH76CP

Cite

RIS / Bibtex

APA

Boztas, A. E., Payza, A. D., Perçin, S., & Şencan, A. (2026). From neonate to adolescent: A review of ovarian mass management in a single center. Ege Tıp Dergisi, 65(3), 547-555. https://doi.org/10.19161/etd.1935423

AMA

1.Boztas AE, Payza AD, Perçin S, Şencan A. From neonate to adolescent: A review of ovarian mass management in a single center. EJM. 2026;65(3):547-555. doi:10.19161/etd.1935423

Chicago

Boztas, Asya Eylem, Ayşe Demet Payza, Süleyman Perçin, and Arzu Şencan. 2026. “From Neonate to Adolescent: A Review of Ovarian Mass Management in a Single Center”. Ege Tıp Dergisi 65 (3): 547-55. https://doi.org/10.19161/etd.1935423.

EndNote

Boztas AE, Payza AD, Perçin S, Şencan A (September 1, 2026) From neonate to adolescent: A review of ovarian mass management in a single center. Ege Tıp Dergisi 65 3 547–555.

IEEE

[1]A. E. Boztas, A. D. Payza, S. Perçin, and A. Şencan, “From neonate to adolescent: A review of ovarian mass management in a single center”, EJM, vol. 65, no. 3, pp. 547–555, Sept. 2026, doi: 10.19161/etd.1935423.

ISNAD

Boztas, Asya Eylem - Payza, Ayşe Demet - Perçin, Süleyman - Şencan, Arzu. “From Neonate to Adolescent: A Review of Ovarian Mass Management in a Single Center”. Ege Tıp Dergisi 65/3 (September 1, 2026): 547-555. https://doi.org/10.19161/etd.1935423.

JAMA

1.Boztas AE, Payza AD, Perçin S, Şencan A. From neonate to adolescent: A review of ovarian mass management in a single center. EJM. 2026;65:547–555.

MLA

Boztas, Asya Eylem, et al. “From Neonate to Adolescent: A Review of Ovarian Mass Management in a Single Center”. Ege Tıp Dergisi, vol. 65, no. 3, Sept. 2026, pp. 547-55, doi:10.19161/etd.1935423.

Vancouver

1.Asya Eylem Boztas, Ayşe Demet Payza, Süleyman Perçin, Arzu Şencan. From neonate to adolescent: A review of ovarian mass management in a single center. EJM. 2026 Sep. 1;65(3):547-55. doi:10.19161/etd.1935423