Nitrate-enhanced TC-99M MIBI Gated SPECT for evaluating viable myocardium and left ventricular functions in patients with coronary artery disease

Volume: 50 Number: 3 September 1, 2011
  • Mür Ö
  • Kgün A
  • Özcan Z
  • Çalkavur İ T
  • Yavuzgil O
  • Özkılıç H
Ege Journal of Medicine Cover
Ege Journal of Medicine
PDF Download
EN TR

Nitrate-enhanced TC-99M MIBI Gated SPECT for evaluating viable myocardium and left ventricular functions in patients with coronary artery disease

Abstract

Aim: In this study, we aimed to research the place of Tc-99m MIBI Gated SPECT used with the sublingual nitrate application in the viability diagnosis. Material and Methods: Fifty patients diagnosed with a coronary artery disease were included in the study. All subjects were evaluated with rest-nitrate Tc-99m MIBI Gated SPECT, echocardiography and angiography. In 50 patients, myocardial perfusion and functional parameters were examined. The five segments myocardial model was used. Results: Normal perfusion was determined in 165 of the 250 segments, there were reversible perfusion defects in 44 and irreversible perfusion defects in 41 segments. If >%50 coronary artery narrowness is accepted as significant stenosis, in 59 of the 85 segments in total in which a perfusion defect was detected, we have detected a significant narrowness in the feeding coronary artery. In the myocardial perfusion scintigraphy (MPS) there was not any significant coronary artery stenosis in 105 of the 165 segments with no perfusion defect. When the findings of the Gated SPECT and echocardiography findings were compared, no statistically significant difference was found between the average EF value (43.8+-29.5) calculated with the QPS/QGS programme and the value obtained from the echocardiographic data (46.3+-29.5). In the subjects with irreversible perfusion defects in MPS, the average EF (39.2±9.4) was lower than the general group average (43.8±29.5). LV functional data obtained with Gated SPECT and echocardiography were found compatible in 219 of the 250 segments. Conclusion: We have concluded that Rest-Nitrate Tc-99m MIBI Gated SPECT is a reliable method in viable myocardium research which gives an advantage ın evauatıng LV functions.

Keywords

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Mür Ö

Kgün A

Özcan Z

Çalkavur İ T

Yavuzgil O

Özkılıç H

Publication Date

September 1, 2011

Submission Date

September 1, 2011

Acceptance Date

-

Published in Issue

Year 2011 Volume: 50 Number: 3

IZ

https://izlik.org/JA78GT52XL

Cite

RIS / Bibtex
Vancouver
1.Mür Ö, Kgün A, Özcan Z, Çalkavur İ T, Yavuzgil O, Özkılıç H. Rest-nitrat TC-99M MIBI Gated Spect’in viabilite ve sol ventrikül fonksiyonlarının değerlendirilmesindeki yeri. EJM [Internet]. 2011 Sep. 1;50(3):159-66. Available from: https://izlik.org/JA78GT52XL

Ege Journal of Medicine enables the sharing of articles according to the Attribution-Non-Commercial-Share Alike 4.0 International (CC BY-NC-SA 4.0) license.