Investigation of the factors influencing primary hypertension in childhood

İlknur Girişgen; Ferah Sönmez

doi:10.19161/etd.414341

TR EN

Investigation of the factors influencing primary hypertension in childhood

Abstract

Aim: Primary hypertension is the most important risk factor for chronic kidney disease in adulthood. The genesis of essential hypertension is likely to be multifactorial. The aim of this study is to investigate the causing factors of primary hypertension detected by ambulatory blood pressure monitoring in children.

Materials and Methods: Fifty-six patients who had blood pressure higher than 90 percentile during the healthy children follow-up and 27 healthy children with the normal blood pressure were included in the study. Twenty-four hour blood pressure measurements with the blood pressure monitor were recorded as the day-night mean blood pressure, the blood pressure loads and the dipper-non-dipper characteristics. Plasma renin levels, serum aldosterone, nitric oxide and endothelin levels and amounts of sodium and potassium excretion in the 24 hour urine and were investigated in all patients and the control group.

Results: Laboratory evaluations of the patients showed that the patient group has higher mean levels of plasma renin, lower mean levels of blood endothelin and mean levels of urinary sodium excretion than the control group.

Conclusion: In the pathogenesis of childhood primary hypertension and white coat hypertension, which were seen in the half of the children diagnosed as primary hypertension, plasma renin and urinary sodium excretion had important roles.

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

İlknur Girişgen ^*
0000-0003-2617-4466
Türkiye

Ferah Sönmez
0000-0003-3027-5032
Türkiye

Publication Date

March 1, 2018

Submission Date

September 29, 2016

Acceptance Date

January 20, 2017

Published in Issue

Year 2018 Volume: 57 Number: 1

DOI

https://doi.org/10.19161/etd.414341

IZ

https://izlik.org/JA95YB42AB

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RIS / Bibtex

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1.İlknur Girişgen, Ferah Sönmez. Investigation of the factors influencing primary hypertension in childhood. EJM. 2018 Mar. 1;57(1):1-7. doi:10.19161/etd.414341

Investigation of the factors influencing primary hypertension in childhood

Çocukluk çağı primer hipertansiyonuna etki eden faktörlerin araştırılması

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Investigation of the factors influencing primary hypertension in childhood

Abstract

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite