Investigation of the factors influencing primary hypertension in childhood

İlknur Girişgen; Ferah Sönmez

doi:10.19161/etd.414341

TR EN

Çocukluk çağı primer hipertansiyonuna etki eden faktörlerin araştırılması

Öz

Amaç: Primer hipertansiyon erişkin çağındaki kronik böbrek yetmezliği için başlıca risk faktörlerinden biridir. Esansiyel hipertansiyon sebepleri multifaktoriyeldir. Amacımız ambulatuar kan basıncı monitorizasyonu yapılmış primer hipertansiyon saptanan çocuklarda etyolojik faktörleri araştırmaktır.

Gereç ve Yöntem: Çalışmaya rutin sağlıklı çocuk kontrollerinde kan basınçları 90 persentilin üzerinde saptanan 56 çocuk ve kan basıncı 90 persentilin altında olan 27 sağlıklı çocuk alındı. Yirmi dört saatlik yaşam içi kan basıncı monitorizasyonu yapılarak gece gündüz kan basıncı ortalamaları, kan basıncı yükleri, dipper-non dipper özellikleri kaydedildi. Plazma renin aktivitesi, serum aldosteron, nitrik oksit, endotelin seviyeleri 24 saatlik idrarda sodyum ve potasyum atılımları karşılaştırıldı.

Bulgular: Laboratuvar değerlendirmelerinde hasta grupta kontrol gruba göre plazma renin aktivitesi yüksek, endotelin seviyesi düşük ve idrar sodyum atılımı yüksek saptandı.

Sonuç: Çocukluk çağı primer hipertansiyonu ve beyaz önlük hipertansiyonunda plazma renin düzeyinin ve idrar sodyum atılımının önemli rol oynadığı sonucuna varılmıştır.

Anahtar Kelimeler

Anahtar Sözcükler: Primer hipertansiyon,endotelin,renin

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

İlknur Girişgen ^*
0000-0003-2617-4466
Türkiye

Ferah Sönmez
0000-0003-3027-5032
Türkiye

Publication Date

March 1, 2018

Submission Date

September 29, 2016

Acceptance Date

January 20, 2017

Published in Issue

Year 1970 Volume: 57 Number: 1

DOI

https://doi.org/10.19161/etd.414341

IZ

https://izlik.org/JA95YB42AB

Cite

RIS / Bibtex

Vancouver

1.İlknur Girişgen, Ferah Sönmez. Investigation of the factors influencing primary hypertension in childhood. EJM. 2018 Mar. 1;57(1):1-7. doi:10.19161/etd.414341

Çocukluk çağı primer hipertansiyonuna etki eden faktörlerin araştırılması

Öz

Anahtar Kelimeler