Comparison of anterior segment parameters between pediatric and adult keratoconus groups

İbrahim Toprak; Cem Yıldırım; Volkan Yaylalı

doi:10.19161/etd.414408

TR EN

Pediatrik ve erişkin keratokonus gruplarında ön segment parametrelerinin karşılaştırılması

Öz

Amaç: Scheimpflug görüntüleme sistemi kullanarak, pediatrik ve erişkin keratokonus grupları arasındaki ön segment ölçümlerindeki farklılıkları belirlemek.

Gereç ve Yöntem: Retrospektif özellikteki bu çalışmaya 133 keratokonuslu hasta ve 101 sağlıklı kontrol olgusu dâhil edildi. Olgular pediatrik ve erişkin olmak üzere gruplandı. Ön kamara derinliği (ÖKD), ön kamara hacmi (ÖKH), ön kamara açısı (ÖKA), pakimetri, kornea hacmi (KH) ve maksimum keratometri (Kmaks) değerleri arasındaki farklılıklar bakımından yaş alt grupları karşılaştırıldı.

Bulgular: Yüz otuz üç keratokonuslu hastanın (56 pediatrik ve 77 erişkin) ve 101 sağlıklı olgunun (41 pediatrik ve 60 erişkin) sağ gözleri incelendi. Her iki grupta, pediatrik olgular erişkin grup ile karşılaştırıldığında daha yüksek ÖKD ve ÖKV değerlerine sahipti (p<0.05). Diğer taraftan, keratokonuslu pediatrik ve erişkin olguların yaş-eşleştirmeli sağlıklı kontrol olgularına kıyasla daha yüksek ÖKD değerine sahip olduğu görüldü (p<0.05). Pediatrik grupta, evre 3 keratokonuslu olgular evre 2 keratokonuslu olgulara göre daha yüksek ÖKD değerine sahipti (p<0.05). Erişkin grupta ise evre 3 keratokonuslu hastaların evre 2 keratokonuslu hastalara göre daha düşük korneal ölçüm değerlerine sahip olduğu saptandı (p<0.05).-

Sonuç: Keratokonus ve kontrol gruplarında yaşla beraber ön kamara parametrelerinin değiştiği görülmektedir. Ancak, tüm yaş gruplarında keratokonuslu gözlerin yaş-eşleştirmeli sağlıklı kontrollere göre daha derin ön kamaraya sahip olduğu anlaşılmaktadır. Ayrıca, pediatrik keratokonus olgularında ÖKD değerindeki artma ilerleme açısından işaret edici olabilir. Diğer taraftan, erişkin keratokonus olgularında hastalık ilerlemesi ile sadece korneal parametre değerlerinin azaldığı görüşündeyiz.

Anahtar Kelimeler

Keratokonus,ön segment,pediatrik,scheimpflug,yaş

Comparison of anterior segment parameters between pediatric and adult keratoconus groups

Abstract

Aim: To determine differences in anterior segment measurements between pediatric and adult keratoconus groups using Scheimpflug imaging system.

Materials and Methods: This retrospective study included 133 patients with keratoconus and 101 healthy controls. Subjects were grouped as pediatric and adult. Differences in anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pachymetry, corneal volume (CV) and maximum keratometry (Kmax) were sought between the age-based subgroups.

Results: Right eyes of the 133 keratoconus patients (56 pediatrics and 77 adults) and 101 healthy controls (41 pediatrics and 60 adults) were reviewed. Pediatric subgroups had significantly higher ACD and ACV compared to those of the adult subgroups in both groups (p<0.05). On the other hand, pediatric and adult keratoconus patients had significantly higher ACD than in the age (subgroup) matched controls (p< 0.05). In the pediatric keratoconus subgroup, eyes with stage 3 keratoconus had significantly deeper ACD than in the eyes with stage 2 keratoconus (p<0.05). However, in the adult group, only corneal parameters were significantly lower in eyes with stage 3 keratoconus compared to those of the eyes with stage 2 keratoconus (p<0.05).

Conclusion: Anterior chamber measurements appear to be altered by aging in both keratoconus and control groups, whereas eyes with keratoconus in all age subgroups appear to have a deeper AC than in the age-matched normals. Moreover, an increase in ACD in pediatric keratoconus might be indicative of progression. However, in the adult keratoconus, corneal parameters appear to decrease with keratoconus progression.

Keywords

Age,anterior segment,keratoconus,pediatrics

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

İbrahim Toprak ^*
0000-0001-6325-7485
Türkiye

Cem Yıldırım
0000-0001-7767-8715
Türkiye

Volkan Yaylalı
0000-0001-8918-7614
Türkiye

Publication Date

March 1, 2018

Submission Date

August 30, 2016

Acceptance Date

December 8, 2018

Published in Issue

Year 2018 Volume: 57 Number: 1

DOI

https://doi.org/10.19161/etd.414408

IZ

https://izlik.org/JA46BE56CR

Cite

RIS / Bibtex

Vancouver

1.İbrahim Toprak, Cem Yıldırım, Volkan Yaylalı. Comparison of anterior segment parameters between pediatric and adult keratoconus groups. EJM. 2018 Mar. 1;57(1):19-25. doi:10.19161/etd.414408