Effects of chronic renal insufficiency on risk factors and results of endoscopy in patients with upper gastrointestinal system bleeding

Ömer Burcak Binicier; Esma Uguztemur

doi:10.19161/etd.417283

TR EN

Üst gastrointestinal sistem kanamalı hastalarda kronik böbrek yetmezliğinin risk faktörleri ve endoskopi sonuçlarına etkisinin değerlendirilmesi

Öz

Amaç: Akut üst gastrointestinal sistem (GİS) kanamaları sık karşılaşılan mortalite ve morbidite nedenlerindendir. Üst GİS kanamalarında ek hastalık varlığı mortalite ile ilişkili bir risk faktörü olup kronik böbrek yetmezliği de (KBY) bunlardan biridir. Bu çalışmamızda, Tepecik Eğitim Araştırma Hastanesi Gastroenteroloji Kliniği’nde Ocak 2016-Ocak 2017 tarihleri arasında yatırılarak tedavi altına alınan üst GİS kanaması geçiren KBY’li hastalar ile üst GİS kanaması geçiren renal yetmezliği olmayan hastalar demografik özellikler, ek hastalık varlığı, ilaç kullanımı, endoskopik sonuçlar, Forrest sınıflaması ve endoskopik girişim gereksinimi ve mortalite açısından karşılaştırmalı olarak incelendi.

Gereç ve Yöntem: Toplam 194 hasta retrospektif olarak değerlendirilmeye alındı. Glomerüler filtrasyon hızı (GFR) 60 mL/dk/1.73 m^2’nin altı olan kronik böbrek yetmezliği grubunda 90 hasta, GFR 60 mL/dk/1.73 m²’nin ve üzerinde olan kontrol grubunda ise 104 hasta çalışmaya dahil edildi.

Bulgular: Çalışma sonucunda KBY grubunun daha yaşlı olduğu ve bu grupta hastaların %96’sında eşlik eden ek hastalık varlığı saptandı. İlaç kullanımı kontrol grubundan daha yüksekti ve en sık kullanılan ilaç olarak aspirin tespit edildi. Olguların % 70’inden fazlasına ilk gün endoskopi uygulandı.

Sonuç: KBY grubunda hastane mortalite oranı kontrol grubuna göre yüksekti (%5.66’ye %2.88, p=0.475) ve total mortalite oranlarımız literatüre göre daha düşük tespit edildi.

Anahtar Kelimeler

Kronik böbrek yetmezliği,gastrointestinal kanama,mortalite.

Effects of chronic renal insufficiency on risk factors and results of endoscopy in patients with upper gastrointestinal system bleeding

Abstract

Aim: Acute upper gastrointestinal system (GIS) bleeding is one of the leading causes of mortality and morbidity. Presence of concomitant disease in upper GIS bleeding is a mortality-associated risk factor, and chronic renal insufficiency (CRI) is one of these concomitant diseases. In the present study, patients with CRI, who had upper GIS bleeding and been treated as inpatient between January 2016 and January 2017 at Tepecik Training and Research Hospital Clinic of Gastroenterology, and the patients that had upper GIS bleeding without renal insufficiency were comparatively investigated in terms of demographic characteristics, presence of concomitant disease, drug usage, endoscopic results, Forrest classification, and need for endoscopic intervention and mortality.

Materials and Methods: A total of 194 patients were retrospectively evaluated. The CRI group with a glomerular filtration rate (GFR) lower than 60 mL/min/1.73 m² comprised 90 patients, whereas the control group with a GFR of 60 mL/min/1.73 m² and higher comprised 104 patients.

Results: As the result of the study, it was determined that CRI group was older and 96% of the patients had a concomitant disease. Drug usage rate was higher than the control group with aspirin used most frequently. Endoscopy was performed on Day 1 in more than 70% of the cases.

Conclusion: Hospital mortality rate was higher in CRI group (5.66% vs 2.88%, p=0.475) with lower total mortality rate found in the present study as compared to the literature.

Keywords

Chronic renal insufficiency,gastrointestinal bleeding,mortality.

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Ömer Burcak Binicier ^*
0000-0003-0040-1982
Türkiye

Esma Uguztemur
0000-0003-1822-3870
Türkiye

Publication Date

December 3, 2018

Submission Date

November 7, 2017

Acceptance Date

December 14, 2017

Published in Issue

Year 2018 Volume: 57 Number: 4

DOI

https://doi.org/10.19161/etd.417283

IZ

https://izlik.org/JA65JT57MN

Cite

RIS / Bibtex

Vancouver

1.Ömer Burcak Binicier, Esma Uguztemur. Effects of chronic renal insufficiency on risk factors and results of endoscopy in patients with upper gastrointestinal system bleeding. EJM. 2018 Dec. 1;57(4):212-7. doi:10.19161/etd.417283