Potentially inappropriate medication usage, fall and comorbidities in geriatric patients diagnosed with chronic subdural hematoma

Emin Taşkıran; Gökhan Gürkan; İsmail Ertan Sevin; Zeliha Fulden Saraç

doi:10.19161/etd.915697

TR EN

Kronik subdural hematom tanılı geriatrik hastalarda potansiyel uygunsuz ilaç kullanımı, düşme ve komorbiditeler

Öz

Amaç: Kronik subdural hematom insidansı, geriatrik yaş grubunda yılda 2-4/100000’dir. Kronik subdural hematom tanılı geriatrik hastalarda, Beers 2019 kriterlerine göre potansiyel uygunsuz ilaç kullanımı ile düşme ve Charlson komorbidite indeksi arasındaki ilişkiyi araştırmayı amaçladık Gereç ve Yöntem: İzmir Katip Çelebi Üniversitesi Hastanesi Beyin ve Sinir Cerrahisi bölümünde son 5 yılda kronik subdural hematom tanısıyla yatan 69 hastanın tıbbi kayıtları yerel fakülte etik kurulunun izniyle retrospektif olarak toplandı. Veriler uygun istatistiksel yöntem kullanılarak SPSSv18 programıyla analiz edildi. Bulgular: Hastaların yaş ortalaması 78,43 ± 7,51 yıl, ortalama Charlson komorbidite indeksi 5,87 ± 2,97 puandı. Düşme olayları 69 kronik subdural hematom vakasının 59’undan (%85,5) sorumluydu. Beers 2019 kriterlerine göre potansiyel uygunsuz ilaç kullanımı 20 hastada (%29) saptandı. Uygunsuz ilaçlar en çok kardiyovasküler sistem sınıfı (%14,5) ve antitrombosit / antikoagulan sınıfa (%14,5) aitti. Hastalar potansiyel uygunsuz ilaç kullanımının olup olmamasına göre iki gruba ayrıldığında, Charlson komorbidite indeksi ilk grupta daha yüksek saptandı (p <0,05). Hastalar düşen ve düşmeyenler olarak iki gruba ayrıldığında, Charlson komorbidite indeksi, demans prevalansı, hastanede yatış süresi, ilaç sayısı, potansiyel uygunsuz ilaç kullanımı, serebrovasküler infarkt ve hemipleji varlığı her iki grupta istatistiksel olarak farklı saptanmadı (p >0,05). Charlson komorbidite indeksi ve kullanılan ilaç sayısı arasında önemli istatistiksel ilişki saptandı (p = 0,001). Sonuç: Retrospektif çalışmamızda düşme, Charlson komorbidite indeksi ve potansiyel uygunsuz ilaç kullanımı arasında önemli bir ilişki saptayamadık. Küçük çalışma grubu, retrospektif kayıtların güvenilmez oluşu, çalışma popülasyonun görece sağlıklı karakteristiğe sahip oluşu kafa karıştırıcı sonuçlara katkıda bulunmuş olabilir.

Anahtar Kelimeler

Potentially inappropriate medication usage, fall and comorbidities in geriatric patients diagnosed with chronic subdural hematoma

Abstract

Aim: The annual incidence of chronic subdural hematoma is 2-4/100000 in geriatric population. We aimed to investigate relationship between potentially inappropriate medication usage according to Beers 2019 criteria, fall and Charlson comorbidity index in geriatric patients diagnosed with chronic subdural hematoma. Materials and Methods: We retrospectively collected medical records of 69 geriatric patients diagnosed with chronic subdural hematoma and hospitalized for the last 5 years in neurosurgery department of Izmir Katip Çelebi University Hospital with the permission of local ethical committee of medical faculty. Data was recorded and analyzed with appropriate method by using SPSS v18. Results: Mean age was 78.43 ± 7.51 years, mean Charlson comorbidity index was 5.87 ± 2.97. Falling events were responsible for 59 (85.5%) out of 69 chronic subdural hematoma cases. Potentially inappropriate medication usage according to Beers 2019 criteria was found in 20 (29%) patients. Inappropriate medications belonged to cardiovascular system (14.5%) class and antiplatelet/anticoagulant (14.5%) class mostly. When group was divided into two groups as patients who used potentially inappropriate medication or not, Charlson comorbidity index was found to be higher in the first group. (p <0.05) When group was divided into two groups as patients who fall or not, no correlation was found in Charlson comorbidity index, dementia prevalence, hospitalization duration, number of medications, potentially inappropriate medication, cerebrovascular infarct and hemiplegia prevalence between these groups (p >0.05). Charlson comorbidity index and number of medications showed significant correlation (p = 0.001). Conclusion: We could not reach a significant correlation between fall, Charlson comorbidity index and potentially inappropriate medication usage in our retrospective study. Small study population size, unreliable medical records and relatively healthy characteristics of population may contribute to crossing results.

Keywords

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Emin Taşkıran ^*
0000-0002-4709-4222
Türkiye

Gökhan Gürkan
0000-0003-1839-1014
Türkiye

İsmail Ertan Sevin
0000-0002-6542-925X
Türkiye

Zeliha Fulden Saraç
0000-0001-9281-2492
Türkiye

Publication Date

April 19, 2021

Submission Date

January 18, 2021

Acceptance Date

March 15, 2021

Published in Issue

Year 2021

DOI

https://doi.org/10.19161/etd.915697

IZ

https://izlik.org/JA22EF66MP

Cite

RIS / Bibtex

Vancouver

1.Emin Taşkıran, Gökhan Gürkan, İsmail Ertan Sevin, Zeliha Fulden Saraç. Potentially inappropriate medication usage, fall and comorbidities in geriatric patients diagnosed with chronic subdural hematoma. EJM. 2021 Apr. 1;18-22. doi:10.19161/etd.915697

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