Araştırma Makalesi

Molar pregnancy frequency of abortions in our clinic and pre-diagnosis success

Cilt: 62 Sayı: 4 18 Aralık 2023
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Molar pregnancy frequency of abortions in our clinic and pre-diagnosis success

Abstract

Aim: Abortion is the termination of pregnancy before the 20th gestational week or when the fetus is below 500 g. Its prevalence is between 50-70% in all pregnancies. Routine histological examination (HE) of abortion materials is controversial in terms of molar pregnancy (MP) diagnosis. This study aims to determine the necessity of HE by evaluating the MP frequency and pre-diagnosis success of abortions in our clinic. Materials and Methods: In this retrospective study, 1007 women whose pregnancy resulted in abortion between 01.01.2019-01.01.2022 and whose demographic data, USG findings, pre-diagnoses and HE results were present, were included. The preliminary diagnoses of patients with CMH and PMH were compared with the HE results. Results: Among the materials sent to pathology for HE, the most common diagnosis was missed abortion with 590 (58.78%). MP was detected in 32 (3.17%) women. Of these, 9 (0.89%) were found to be CMH, while 23 (2.28%) were PMH. While 6 (66.6%) of 9 patients diagnosed with CMD were prediagnosed with CMD, 10 (43.37%) out of 23 patients diagnosed with PMH were prediagnosed as PMH. Conclusion: Since the prevalence of MP is 3.17% and there is a high inconsistency between the pre-diagnosis and the result of HE, we recommend that all abortion materials be performed with HE.

Keywords

Kaynakça

  1. 1. Hoffman BL: Williams Gynecology, THIRDEDITION. Edited by McGraw-Hill Education, 2016,
  2. 2. Jauniaux E, Burton G: Pathophysiology of histological changes in early pregnancy loss, Placenta 2005, 26:114-123
  3. 3. Robinson GE: Pregnancy loss, Best practice & research Clinical obstetrics & gynaecology 2014, 28:169-178
  4. 4. Quenby S, Gallos ID, Dhillon-Smith RK, Podesek M, Stephenson MD, Fisher J, Brosens JJ, Brewin J, Ramhorst R, Lucas ES: Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss, The Lancet 2021, 397:1658-1667
  5. 5. Heath V, Chadwick V, Cooke I, Manek S, MacKenzie I: Should tissue from pregnancy termination and uterine evacuation routinely be examined histologically?, BJOG: An International Journal of Obstetrics & Gynaecology 2000, 107:727-730
  6. 6. Tantengco OAG, De Jesus II FCC, Gampoy EFS, Ornos EDB, Vidal Jr MS, Cagayan MSFS: Molar pregnancy in the last 50 years: A bibliometric analysis of global research output, Placenta 2021, 112:54-61
  7. 7. Genest DR: Partial hydatidiform mole: clinicopathological features, differential diagnosis, ploidy and molecular studies, and gold standards for diagnosis, International journal of gynecological pathology 2001, 20:315-322
  8. 8. Obstetricians ACo, Gynecologists: ACOG Practice Bulletin No. 200: early pregnancy loss, Obstetrics and Gynecology 2018, 132:e197-e207

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Yayımlanma Tarihi

18 Aralık 2023

Gönderilme Tarihi

7 Ekim 2022

Kabul Tarihi

24 Aralık 2022

Yayımlandığı Sayı

Yıl 2023 Cilt: 62 Sayı: 4

DOI

https://doi.org/10.19161/etd.1185567

IZ

https://izlik.org/JA84JW34FF

Kaynak Göster

RIS / Bibtex
Vancouver
1.Özge Şehirli Kıncı, Mehmet Ferdi Kıncı, Mehmet Onur Arslaner, Firangiz Mirzazada, Melek Ünçel. Molar pregnancy frequency of abortions in our clinic and pre-diagnosis success. ETD. 01 Aralık 2023;62(4):481-5. doi:10.19161/etd.1185567

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