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Angiolipoleiomyoma of the Uterus: A rare case report and review of the literature

Cilt: 64 Sayı: 3 8 Eylül 2025
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Angiolipoleiomyoma of the Uterus: A rare case report and review of the literature

Abstract

The aim of this study is to present a case of angiolipoleiomyoma (ALLM), a rare benign tumor of the uterus, compare it with similar cases in the literature, and contribute to the diagnosis, treatment, and classification process of this tumor. A 40-year-old diabetic woman, gravida 4 para 4, presented to the emergency department with prolonged vaginal bleeding accompanied by dull lower abdominal pain. On admission, her hemoglobin level was 6.8 g/dL and hematocrit were 23.9%. Gynecological examination revealed a relaxed abdomen and a semi-mobile, non-tender fullness in the right adnexal region on bimanual palpation. Further history indicated that the patient had been experiencing prolonged abnormal uterine bleeding as the primary symptom, with the dull pain emerging more recently. Following urgent blood transfusion, pelvic ultrasonography revealed a heterogeneous, hyperechoic cystic-solid mass located on the right side of the uterus. Pelvic magnetic resonance imaging (MRI) showed a lobulated mass measuring 90×52 mm, slightly hyperintense on T1-weighted sequences, and demonstrating heterogeneous enhancement after contrast administration. The mass was surgically removed via a Pfannenstiel incision. Histopathological examination confirmed the diagnosis of ALLM. A comprehensive literature search was conducted using the keyword "angiolipoleiomyoma" in PubMed and Google Scholar up to June 2024. Animal studies were excluded from the review. As a result, 31 cases were identified, and diagnoses and classifications were evaluated according to the most recent histopathological criteria. ALLM is a rare, typically asymptomatic, and benign tumor of the uterus. Definitive diagnosis is made through histopathological examination. The information from the literature and the presented case highlights the diagnostic characteristics of this tumor and contributes to future classification studies. Note: This study was presented as a poster at the 15th Turkish-German Gynecology Congress, held on April 23–27, 2025, at Rixos Sungate, Antalya, Türkiye.

Keywords

Kaynakça

  1. Yaegashi H, Moriya T, Soeda S, et al. Uterine angiomyolipoma: case report and review of the literature. Pathol Int. 2001;51(11):896–901.
  2. McKeithen W, Shinner J, Michelsen J. Hamartoma of the uterus. Obstet Gynecol. 1964;24:231–4.
  3. Kurman RJ, Carcangiu ML, Herrington CS, Young RH, editors. WHO Classification of Tumours of Female Reproductive Organs. 4th ed. Lyon: IARC; 2014.
  4. Ren R, Wu H. Pathologic quiz CASE: a 40-year-old woman with an unusual uterine tumor. Arch Pathol Lab Med. 2004;128:e31–2.
  5. Cendek BD, Avsar AF, Ergen EB, et al. Rarely seen benign tumor of the uterus, angiolipoleiomyoma: A case report. Bakirkoy Tip Derg. 2018;14:142–5.
  6. Bacanakgil BH, Deveci M. Angiolipoleiomyoma of the uterus. J Turk Ger Gynecol Assoc. 2016;17(Suppl 1):S176–7.
  7. Braun HL, Wheelock JB, et al. Sonographic evaluation of a uterine angiolipoleiomyoma. J Clin Ultrasound. 2002;30:241–4.
  8. Sánchez-Iglesias JL, Capote S, et al. A giant superinfected uterine angioleiomyoma with distant septic metastases. Arch Gynecol Obstet. 2019;300(4):841–7.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Patoloji , Kadın Hastalıkları ve Doğum

Bölüm

Olgu Sunumu

Yazarlar

Yayımlanma Tarihi

8 Eylül 2025

Gönderilme Tarihi

30 Nisan 2025

Kabul Tarihi

24 Temmuz 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 64 Sayı: 3

DOI

https://doi.org/10.19161/etd.1673714

IZ

https://izlik.org/JA46ZX72YZ

Kaynak Göster

RIS / Bibtex
Vancouver
1.Zeynep Yavaş Yücel, Tural Ismayilov, Ayşe Filiz Gokmen Karasu. Angiolipoleiomyoma of the Uterus: A rare case report and review of the literature. ETD. 01 Eylül 2025;64(3):557-62. doi:10.19161/etd.1673714

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