Araştırma Makalesi

Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery

Cilt: 65 Sayı: 3 3 Eylül 2026
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Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery

Öz

Aim: The temporo–parieto–occipital junction (TPOJ) represents a critical convergence zone of the dorsal and ventral language pathways. Preservation of these tracts is essential during surgery for lesions involving this region. The aim of this study is to define the microsurgical anatomy of the dorsal and ventral language pathways at the TPOJ using the fiber dissection technique and to propose a surgical strategy based on the principles of fiber separation. Materials and Methods: Three formalin-fixed adult human cadaveric brains (six hemispheres) and two silicone-injected adult human cadaveric heads (four sides) were prepared using the Klingler fiber dissection technique. Stepwise microscopic dissections were performed from the cortical surface toward the deep white matter. The spatial relationships of the superior longitudinal fasciculus (SLF II–III), arcuate fasciculus (AF), inferior fronto-occipital fasciculus (IFOF), middle longitudinal fasciculus (MdLF), and extreme capsule (ExtC) were analyzed. Special attention was given to the depth, orientation, and natural separation planes between the dorsal and ventral language pathways. Results: The dorsal language system, mainly composed of SLF II–III and the arcuate fasciculus, was identified in all dissections as a superficial-to-intermediate layer beneath the U-fibers. The ventral language pathways, including the IFOF, MdLF, and extreme capsule system, were observed in deeper and more medial planes throughout the dissections. Between the dorsal and ventral systems, a distinct separation corridor was consistently identified, particularly along the interface between the arcuate fasciculus and the IFOF, across different cadaveric specimens. This corridor corresponded to a potential surgical plane for fiber separation techniques. Conclusions: At the TPOJ, the dorsal and ventral language pathways demonstrate a layered anatomical organization with distinct separation planes. Recognition of these natural separations may contribute to the development of fiber-preserving microsurgical strategies.

Anahtar Kelimeler

Destekleyen Kurum

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors

Etik Beyan

This study was conducted on donated human cadaveric specimens in the Microneurosurgery Laboratory of the Department of Neurosurgery, Istanbul University–Cerrahpaşa, Cerrahpaşa Faculty of Medicine, under institutional regulations. As the study involved only cadaveric anatomical dissections and no living human participants or patient data, formal ethics committee approval was not required. All procedures were performed in accordance with institutional guidelines and the ethical principles of the Declaration of Helsinki.

Teşekkür

We thank Medtronic, Inc. and this company’s representation in Turkey, for providing the Midas Rex legend system (Medtronic, Inc., Minneapolis, MN, USA) to the Microsurgical Neuroanatomy Laboratory in Istanbul University–Cerrahpasa, Turkey, Department of Neurosurgery.

Kaynakça

  1. 1. De Benedictis A, Duffau H, Paradiso B, Grandi E, Balbi S, Granieri E, et al. Anatomo-functional study of the temporo-parieto-occipital region: Dissection, tractographic and brain mapping evidence from a neurosurgical perspective. J Anat 2014;225(2):132-51.
  2. 2. Biceroglu H, Karadag A. Neuroanatomical aspects of the temporo-parieto-occipital junction and new surgical strategy to preserve the associated tracts in junctional lesion surgery: Fiber separation technique. Turk Neurosurg 2019;29(6):864-74.
  3. 3. Shekari E, Nozari N. A narrative review of the anatomy and function of the white matter tracts in language production and comprehension. Front Hum Neurosci 2023;17:1139292.
  4. 4. Martino J, da Silva-Freitas R, Caballero H, Marco de Lucas E, García-Porrero JA, Vázquez-Barquero A. Fiber dissection and diffusion tensor imaging tractography study of the temporoparietal fiber intersection area. Neurosurgery 2013;72(Suppl Operative):87-97.
  5. 5. Chang EF, Raygor KP, Berger MS. Contemporary model of language organization: an overview for neurosurgeons. J Neurosurg 2015;122(2):250-61.
  6. 6. Dick AS, Bernal B, Tremblay P. The language connectome. Neuroscientist 2014;20(5):453-67.
  7. 7. Saur D, Kreher BW, Schnell S, Kümmerer D, Kellmeyer P, Vry MS, et al. Ventral and dorsal pathways for language. Proc Natl Acad Sci U S A 2008;105(46):18035-40.
  8. 8. Rauschecker JP. Ventral and dorsal streams in the evolution of speech and language. Front Evol Neurosci 2012;4:7.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri (Diğer)

Bölüm

Araştırma Makalesi

Yazarlar

Yayımlanma Tarihi

3 Eylül 2026

Gönderilme Tarihi

18 Şubat 2026

Kabul Tarihi

15 Mayıs 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 65 Sayı: 3

DOI

https://doi.org/10.19161/etd.1892578

IZ

https://izlik.org/JA43WF48LW

Kaynak Göster

RIS / Bibtex
APA
Bilgin, B., Yüncü, M. E., Güler, E., Karadag, A., & Tanrıöver, N. (2026). Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery. Ege Tıp Dergisi, 65(3), 477-486. https://doi.org/10.19161/etd.1892578
AMA
1.Bilgin B, Yüncü ME, Güler E, Karadag A, Tanrıöver N. Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery. ETD. 2026;65(3):477-486. doi:10.19161/etd.1892578
Chicago
Bilgin, Berra, Mustafa Eren Yüncü, Erman Güler, Ali Karadag, ve Necmettin Tanrıöver. 2026. “Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery”. Ege Tıp Dergisi 65 (3): 477-86. https://doi.org/10.19161/etd.1892578.
EndNote
Bilgin B, Yüncü ME, Güler E, Karadag A, Tanrıöver N (01 Eylül 2026) Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery. Ege Tıp Dergisi 65 3 477–486.
IEEE
[1]B. Bilgin, M. E. Yüncü, E. Güler, A. Karadag, ve N. Tanrıöver, “Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery”, ETD, c. 65, sy 3, ss. 477–486, Eyl. 2026, doi: 10.19161/etd.1892578.
ISNAD
Bilgin, Berra - Yüncü, Mustafa Eren - Güler, Erman - Karadag, Ali - Tanrıöver, Necmettin. “Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery”. Ege Tıp Dergisi 65/3 (01 Eylül 2026): 477-486. https://doi.org/10.19161/etd.1892578.
JAMA
1.Bilgin B, Yüncü ME, Güler E, Karadag A, Tanrıöver N. Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery. ETD. 2026;65:477–486.
MLA
Bilgin, Berra, vd. “Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery”. Ege Tıp Dergisi, c. 65, sy 3, Eylül 2026, ss. 477-86, doi:10.19161/etd.1892578.
Vancouver
1.Berra Bilgin, Mustafa Eren Yüncü, Erman Güler, Ali Karadag, Necmettin Tanrıöver. Fiber dissection anatomy of the dorsal and ventral language pathways at the temporo–parieto–occipital junction: Implications for fiber separation surgery. ETD. 01 Eylül 2026;65(3):477-86. doi:10.19161/etd.1892578

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