Germ hücreli tümörlere eşlik eden intratübüler germ hücre neoplazisi

Cilt: 46 Sayı: 2 1 Haziran 2007
  • Bilir G
  • Çakır E
  • Benzer E
  • Pak I
  • Kebat T
  • Ardıç F
Ege Tıp Dergisi Kapak
Ege Tıp Dergisi
PDF İndir
EN TR

Intratubular germ cell neoplasia accompanying germ cell tumors

Abstract

Intratubular germ cell neoplasia is considered a preinvasive stage of testicular germ cell malignancy because of its association with invasive germ cell tumors. In this study, the frequency of intratubular germ cell neoplasia in testicular germ cell tumors and immunohistochemical stains for p53, placental alkaline phosphatase and histochemical stains for periodic-acid Schiff (PAS)- diastase and argyrophilic nucleolar organizer regions were evaluated. 69 of 158 testicular germ cell tumors, residual seminiferous tubules were found at the periphery of the invasive neoplastic foci. Intratubular germ cell neoplasia was detected histomorphologicaly in 65 cases. Neoplastic intratubuler germ cells were reactive with placental alkaline phosphatase and positive for glicogene with periodic-acid Schiff - diastase stain in 63 (%96.9) of these cases. In 48 cases (%69), atypical germ cells were rective with p53. Argyrophilic nucleolar organizer regions count for the 63 cases which have intratubuler germ cell neoplasia was 5.83. It is concluded that intratubular germ cell neoplasia is present in most invasive germ cell tumors and the periodic-acid Schiff - diastase and placental alkaline phosphatase stains are useful in detecting intratubuler germ cell neoplasia.

Keywords

Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Bilir G

Çakır E

Benzer E

Pak I

Kebat T

Ardıç F

Yayımlanma Tarihi

1 Haziran 2007

Gönderilme Tarihi

1 Haziran 2007

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 1970 Cilt: 46 Sayı: 2

IZ

https://izlik.org/JA56XJ72SE

Kaynak Göster

RIS / Bibtex
Vancouver
1.Bilir G, Çakır E, Benzer E, Pak I, Kebat T, Ardıç F. Germ hücreli tümörlere eşlik eden intratübüler germ hücre neoplazisi. ETD [Internet]. 01 Haziran 2007;46(2):73-7. Erişim adresi: https://izlik.org/JA56XJ72SE

Ege Tıp Dergisi, makalelerin Atıf-Gayri Ticari-Aynı Lisansla Paylaş 4.0 Uluslararası (CC BY-NC-SA 4.0) lisansına uygun bir şekilde paylaşılmasına izin verir.