Ergin dişi sıçanlarda submandibular bez üzerine overektominin etkileri

Cilt: 50 Sayı: 1 1 Mart 2011
  • Uyanıkgil Y
  • Türkkozan N Y
  • Balcıoğlu H A
  • Ateş U
  • Özel S
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The effects of ovariectomy on the submandibular gland in young female adult rats

Abstract

Aim: The salivary gland is one of the target tissues of estrogen. The aim of the study was to investigate the effects of ovariectomy on the stimulated salivary flow rate and morphology of the submandibular gland in sexually mature young rats. Material and Methods: 72 Female Wistar albino rats of 15 weeks of age were used in this study. Submandibular ducts were cannulated intraorally with polyethylene tubes and stimulated salivary flow rates were determined at 1st, 2nd, 4th, 8th, 12th and 16th weeks after the ovariectomy. Histological sections of the submandibular glands were stained and assessed under a light microscope. The diameters of the acinar cells and parenchyma/stroma ratio were calculated using a software system. Results: The stimulated submandibular flow rate was found to be significantly decreased at 1st, 2nd, 4th, 8th, 12th and 16th weeks after the ovariectomy. A decrease in the parenchymal structures and acinar cells, an increase in the interstitial connective tissue and fatty degeneration of the gland were observed. Conclusion: Ovariectomy leads to a decrease in stimulated submandibular salivary flow rate. The changes in gland morphology may be responsible for the decrease in salivary flow rate in young adult rats.

Keywords

Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

-

Yazarlar

Uyanıkgil Y

Türkkozan N Y

Balcıoğlu H A

Ateş U

Özel S

Yayımlanma Tarihi

1 Mart 2011

Gönderilme Tarihi

1 Mart 2011

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2011 Cilt: 50 Sayı: 1

IZ

https://izlik.org/JA97XC94EJ

Kaynak Göster

RIS / Bibtex
Vancouver
1.Uyanıkgil Y, Türkkozan N Y, Balcıoğlu H A, Ateş U, Özel S. Ergin dişi sıçanlarda submandibular bez üzerine overektominin etkileri. ETD [Internet]. 01 Mart 2011;50(1):7-11. Erişim adresi: https://izlik.org/JA97XC94EJ

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