Lenfoma hastalarında yetersiz hematopoiteik kök hücre mobilizasyonu için risk faktörleri

Cilt: 56 Sayı: 1 1 Mart 2017
  • Asu Fergün Yılmaz
  • Murat Tombuloglu
  • Ayhan Dönmez
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The risk factors for a poor hematopoietic stem cell mobilization in lymphoma patients

Abstract

Aim: Poor mobilization is an important problem in autologous stem cell transplantation. The ratio of poor mobilization is higher in lymphoma patients. There is limited data about poor mobilization in lymphoma patients. We aimed to identify the possible risk factors for poor mobilization using data from 57 lymphoma patients. Materials and Methods: We retrospectively reviewed the data of 57 lymphoma patients (40 with non-Hodgkin lymphoma and 17 with Hodgkin lymphoma) who have been mobilized during 1998 - 2011. Patient data were recruited from the archives of the hematology clinic. Results: We documented poor mobilization in 13 (22.8%) patients. Bone marrow involvement (odds ratio [OR] =15.52, p=0.002) and being treated with more than ten cycles of chemotherapies (OR=6.25, p=0.04) were found to be possible risk factors. Conclusion: Leukapheresis staff should be aware of the increased risk of poor mobilization in these cases and remobilization strategies should be considered from the beginning in these patients with risk factors for more effective resource utilization.

Keywords

Ayrıntılar

Birincil Dil

Türkçe

Konular

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Bölüm

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Yazarlar

Asu Fergün Yılmaz

Murat Tombuloglu

Ayhan Dönmez

Yayımlanma Tarihi

1 Mart 2017

Gönderilme Tarihi

1 Mart 2017

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2017 Cilt: 56 Sayı: 1

Kaynak Göster

Vancouver
1.Asu Fergün Yılmaz, Murat Tombuloglu, Ayhan Dönmez. Lenfoma hastalarında yetersiz hematopoiteik kök hücre mobilizasyonu için risk faktörleri. ETD. 01 Mart 2017;56(1):6-10. doi:10.19161/etd.344290

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