A novel predictor in acute kidney injury: Neutrophil to lymphocyte count
Abstract
Aim: Acute Kidney injury (AKI) represents a clinical condition reflecting systemic inflammation. Neutrophil-to-lymphocyte ratio (NLR) is novel prognostic marker in various inflammatory conditions. In this retrospective cohort we evaluated two hundred and thirteen AKI patients.
Materials and Methods: The patients’ baseline values on admission, final values at discharge and after discharging during follow-up period in outpatient clinic until six months to one year were recorded. NLR change during follow-up period after hospitalization was also examined.
Results: It has been shown that, final NLR and timely changed NLR during hospital course are significant mortality predictors in AKI patients both in univariate and mutually adjusted multivariate logistic regression analysis. To predict mortality, we showed that, level of 9.90 point for final NLR has 73% sensitivity and 87% specifity as compared to value below in ROC analysis (HR: 7.31, CI 3.36-15.91; p<0.001).
Conclusion: NLR may be a novel screening tool on patiens' mortality for AKI patients during their hospital course.
Keywords
Kaynakça
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Ayrıntılar
Birincil Dil
İngilizce
Konular
-
Bölüm
Araştırma Makalesi
Yazarlar
Devrim Bozkurt
*
0000-0003-4557-3390
Türkiye
Aslı Kılavuz
0000-0002-0474-9911
Türkiye
Mehmet Berktaş
0000-0003-0604-9449
Türkiye
Fehmi Akçiçek
0000-0003-2583-4709
Türkiye
Yayımlanma Tarihi
1 Mart 2018
Gönderilme Tarihi
21 Ağustos 2016
Kabul Tarihi
16 Aralık 2016
Yayımlandığı Sayı
Yıl 1970 Cilt: 57 Sayı: 1