Immune checkpoint inhibitors related connective tissue diseases
Abstract
Immune checkpoint inhibitors are drugs that used in cancer treatment and increased in the use day by day. Immune-related adverse events of almost any organs are reported with these drugs. Hepatitis, colitis, pneumonitis, rash, thyroiditis, hypophysitis are the most common. Immune-related adverse events are generally mild to moderate, with a frequency greater than 90%. Although the rheumatologic adverse events are reported less than others, the true incidence of these adverse events is not fully known. Arthralgia and arthritis are the most commonly reported rheumatic immune-related adverse events in immune checkpoint inhibitors. In addition, there are case reports related to myositis, sikka syndrome, scleroderma and sarcoidosis. Increased awareness of rheumatic adverse events is important for early diagnosis and treatment of these cases.
Keywords
Kaynakça
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Ayrıntılar
Birincil Dil
Türkçe
Konular
-
Bölüm
Diğer
Yazarlar
Ayten Yazıcı
*
0000-0003-2167-4509
Türkiye
Yayımlanma Tarihi
25 Ekim 2019
Gönderilme Tarihi
19 Ekim 2018
Kabul Tarihi
15 Ağustos 2019
Yayımlandığı Sayı
Yıl 1970